Provide technical support for analytical methodologies in commercial and development phases of API manufacturing. This role will be based out of our North Chicago facility. This individual will support the development, validation and transfer of analytical test methods to commercial manufacturing sites, contribute to regulatory submissions and submission responses for new products or product changes and provide troubleshooting/continuous improvement support to commercial testing laboratories. **This position is part of a hierarchical continuum and will be filled at a level (Grade 13 or 15) consistent with the education and experience of the best candidate. ** Key Responsibilities Include: Validate, transfer and troubleshoot analytical methods, including raw materials, in-process, intermediate, API, excipient and drug product testing Interpret analytical data, recommend specifications and methods for process or product characterization Anticipate, recognize and resolve simple and complex technical issues through job knowledge, use of technical resources including technical literature and experts and well formulated, logical experimentation. May serve as analytical representative to cross functional project teams; actively participate in team efforts and contribute to technical evaluations and solutions Author, review and verify validation and transfer protocols and reports Author quality and regulatory test method documents Write/co-author memos and scientific reports in support of Regulatory Submissions, Regulatory Field Alerts and support quality control and manufacturing documents Manage analytical projects. Establish schedules and direct activities of other scientists and non-scientists as well as provide training and development for others. Serve as a liaison between functional groups and external customers for analytical development, transfer, troubleshooting and improvement efforts. Proactively and cooperatively communicate with peers and management to ensure awareness of progress and issues; recommend solutions when issues arise Capable of working with significant independence Maintain and meet the highest standards in quality, customer service and regulatory compliance. Follow, understand and comply with AbbVie SOP's and policies on cGMP's and safety. Maintain a clean, safe and organized lab area, and potentially assume responsibility to ensure that others maintain their lab areas Basic: BS degree in Science or related degree with 3-5 years of experience preferred. OR MS degree in Science or related degree with 2-4 years of experience preferred. OR Ph.D. / Pharm.D. in Science ore related field; with 1-2 years of experience preferred Has proficiency in standard office software and analytical testing experience in wet chemisty, gas and liquid chromatography and/or spectrometric test methods. A working knowledge of Empower, LIMS, eLN, Nugenesis, Soltraqs and Attache is highly desirable. Is knowledgeable of cGLP requirements and familiar with ICH guideline Has strong problem solving and organizational skill Excellent communication (oral and written) and interpersonal skills; ability to work well with a wide range of functional groups including R&D, QC, QA, Regulatory Affairs, and Commercial Operations Can function both independently and as a team player Must be adaptable and able to operate effectively in a highly dynamic environment Equal Opportunity Employer Minorities/Women/Veterans/Disabled
Feb 21, 2019
Full time
Provide technical support for analytical methodologies in commercial and development phases of API manufacturing. This role will be based out of our North Chicago facility. This individual will support the development, validation and transfer of analytical test methods to commercial manufacturing sites, contribute to regulatory submissions and submission responses for new products or product changes and provide troubleshooting/continuous improvement support to commercial testing laboratories. **This position is part of a hierarchical continuum and will be filled at a level (Grade 13 or 15) consistent with the education and experience of the best candidate. ** Key Responsibilities Include: Validate, transfer and troubleshoot analytical methods, including raw materials, in-process, intermediate, API, excipient and drug product testing Interpret analytical data, recommend specifications and methods for process or product characterization Anticipate, recognize and resolve simple and complex technical issues through job knowledge, use of technical resources including technical literature and experts and well formulated, logical experimentation. May serve as analytical representative to cross functional project teams; actively participate in team efforts and contribute to technical evaluations and solutions Author, review and verify validation and transfer protocols and reports Author quality and regulatory test method documents Write/co-author memos and scientific reports in support of Regulatory Submissions, Regulatory Field Alerts and support quality control and manufacturing documents Manage analytical projects. Establish schedules and direct activities of other scientists and non-scientists as well as provide training and development for others. Serve as a liaison between functional groups and external customers for analytical development, transfer, troubleshooting and improvement efforts. Proactively and cooperatively communicate with peers and management to ensure awareness of progress and issues; recommend solutions when issues arise Capable of working with significant independence Maintain and meet the highest standards in quality, customer service and regulatory compliance. Follow, understand and comply with AbbVie SOP's and policies on cGMP's and safety. Maintain a clean, safe and organized lab area, and potentially assume responsibility to ensure that others maintain their lab areas Basic: BS degree in Science or related degree with 3-5 years of experience preferred. OR MS degree in Science or related degree with 2-4 years of experience preferred. OR Ph.D. / Pharm.D. in Science ore related field; with 1-2 years of experience preferred Has proficiency in standard office software and analytical testing experience in wet chemisty, gas and liquid chromatography and/or spectrometric test methods. A working knowledge of Empower, LIMS, eLN, Nugenesis, Soltraqs and Attache is highly desirable. Is knowledgeable of cGLP requirements and familiar with ICH guideline Has strong problem solving and organizational skill Excellent communication (oral and written) and interpersonal skills; ability to work well with a wide range of functional groups including R&D, QC, QA, Regulatory Affairs, and Commercial Operations Can function both independently and as a team player Must be adaptable and able to operate effectively in a highly dynamic environment Equal Opportunity Employer Minorities/Women/Veterans/Disabled
Drug Product Development is responsible for understanding the biopharmaceutical properties of candidate molecules for translation into the design and development of patient centric dosage forms. We have a challenging opportunity for a Senior Scientist based in the Formulation Sciences group in North Chicago, IL AbbVie is seeking a highly motivated, collaborative scientist to guide the design and characterization of innovative pharmaceutical formulations for pre-clinical and clinical applications Key responsibilities include: Interface with Discovery and Development project teams to aid the identification of new drug candidates Design and characterize novel pharmaceutical formulations Collaborate with preclinical scientists to characterize the biopharmaceutical properties of drug candidates Conceive and execute laboratory studies contributing to design and understanding of oral formulations in clinical and pre-clinical development Level will be based on education & years of experience. Basic: PhD and no experience necessary (PhD required) possesses thorough theoretical and practical understanding of own scientific discipline Preferred: Strong knowledge of physiological barriers to intestinal absorption of small molecules, including potential transport and metabolism pathways. Strong knowledge in the characterization of the biopharmaceutical properties of small molecules. Working knowledge of typical formulation approaches and routes of administration across multiple species. Fundamental understanding of physicochemical properties as related to drug delivery and formulation design. Excellent oral and written communication skills. Demonstrated ability to work collaboratively in cross-functional team setting. Key AbbVie Competencies: Builds strong relationships with peers and cross functionally with partners outside of the team to enable higher performance. Learns fast, grasps the "essence" and can change the course quickly where indicated. Raises the bar and is never satisfied with the status quo. Creates a learning environment, open to suggestions and experimentation for improvement. Embraces the ideas of others, nurtures innovation and manages innovation to reality. Equal Opportunity Employer Minorities/Women/Veterans/Disabled
Feb 21, 2019
Full time
Drug Product Development is responsible for understanding the biopharmaceutical properties of candidate molecules for translation into the design and development of patient centric dosage forms. We have a challenging opportunity for a Senior Scientist based in the Formulation Sciences group in North Chicago, IL AbbVie is seeking a highly motivated, collaborative scientist to guide the design and characterization of innovative pharmaceutical formulations for pre-clinical and clinical applications Key responsibilities include: Interface with Discovery and Development project teams to aid the identification of new drug candidates Design and characterize novel pharmaceutical formulations Collaborate with preclinical scientists to characterize the biopharmaceutical properties of drug candidates Conceive and execute laboratory studies contributing to design and understanding of oral formulations in clinical and pre-clinical development Level will be based on education & years of experience. Basic: PhD and no experience necessary (PhD required) possesses thorough theoretical and practical understanding of own scientific discipline Preferred: Strong knowledge of physiological barriers to intestinal absorption of small molecules, including potential transport and metabolism pathways. Strong knowledge in the characterization of the biopharmaceutical properties of small molecules. Working knowledge of typical formulation approaches and routes of administration across multiple species. Fundamental understanding of physicochemical properties as related to drug delivery and formulation design. Excellent oral and written communication skills. Demonstrated ability to work collaboratively in cross-functional team setting. Key AbbVie Competencies: Builds strong relationships with peers and cross functionally with partners outside of the team to enable higher performance. Learns fast, grasps the "essence" and can change the course quickly where indicated. Raises the bar and is never satisfied with the status quo. Creates a learning environment, open to suggestions and experimentation for improvement. Embraces the ideas of others, nurtures innovation and manages innovation to reality. Equal Opportunity Employer Minorities/Women/Veterans/Disabled
Pharmacyclics is committed to the development and commercialization of novel therapies intended to improve the quality and duration of life and to resolve serious unmet medical needs for cancer patients. Pharmacyclics is a wholly-owned subsidiary of AbbVie (NYSE:ABBV), a global, research-based biopharmaceutical company. Oncology is a key therapeutic area for AbbVie, with a portfolio consisting of three marketed products and a pipeline containing multiple promising new molecules that are being studied in more than 200 clinical trials for over 20 different types of cancer. More than 1,200 Pharmacyclics and AbbVie research scientists, clinicians, marketing, operations and corporate professionals work in the San Francisco Bay Area. They combine their expertise in immuno-oncology, stem cells, and cell-signaling with their knowledge of bispecific antibodies, antibody-drug conjugates (ADCs), and covalent-inhibitor technologies to discover and develop novel cancer treatments. Together, we are striving to outsmart cancer. To learn more about us, please visit us at Pharmacyclics is seeking a Senior Scientist III, Medicinal Chemistry. We are expanding a world-class medicinal chemistry team to drive innovation in small molecule oncology Discovery. You will work in a rapidly-growing organization, with the goal of identifying clinical candidates in the oncology field to address unmet medical needs. The ideal candidate should have a deep passion for drug discovery with a track-record of accomplishments as a synthetic chemist, demonstrate outstanding problem-solving skills, and curiosity to learn and develop as a medicinal chemist. Primary Job Function : Other than being an individual contributor of the medicinal chemistry team, direct research and/or project activities and professional development of a group of scientists within the individual's area of expertise by effectively mentoring, guiding and/or supervising scientific personnel. Expertise in synthetic organic chemistry and medicinal chemistry are essential for this position. By align with the project strategy, independently as well as influencing group members to conceive and communicate novel medicinal chemistry ideas, execute, drive the SAR optimization cycle to achieve project deliverables. Core Job Responsibilities : Maintain a high level of productivity in the laboratory setting by generating high impact compounds. Demonstrate the ability to resolve key project hurdles and assumptions by effectively utilizing available information and technical expertise. Seize opportunities to pursue project relevant leads that are in line with the group's strategy, and be responsible for developing new SAR/series. Effectively function as a principle investigator, generating original technical ideas and research or development strategies. Generate new scientific proposals and lead those efforts. Anticipate and critically evaluate scientific or regulatory advances or competitive threats and respond with appropriate new strategies. Demonstrate creative 'out of the box' thinking to solve difficult problems and champion new technologies to achieve project goals. Independently responsible for project science within his/her area of expertise on one or more project teams. Position Accountability/Scope : Demonstrate a high degree of responsibility in maintaining scientific standards, and safe laboratory practices. Participate in establishing project goals, defining short and long-term scientific strategies, and contribute to the generation of project-related documents and presentations. Keep accurate and current records of research and/or project related activities according to AbbVie policies. Internal/External Contacts and Interactions : Recognized and sought out as an expert in his/her discipline within the company and possibly externally. Use external information to gain competitive intelligence. Act as advocate to integrate this knowledge into the group's research efforts. Collaborate with functional and technical experts to facilitate scientific achievement. Recognized and sought out as an expert in his/her discipline within the company and possibly externally. Primary author of publications, presentations, regulatory documents and/or primary inventor of patents. Present at leading scientific conferences. Responsible for compliance with applicable Corporate and Divisional Policies and procedures. Qualifications: PhD in Organic/Medicinal Chemistry. Postdoctoral or pharmaceutical industry experience desirable; 6+(PhD with Postdoc) years of industrial experience Demonstrated ability to function as a principle investigator, generating original technical ideas and research or development strategies. Demonstrated creative 'out of the box' thinking to solve difficult technical problems and champion new technologies to achieve project goals. Experience in synthetic methods development, target-oriented synthesis, chemical biology, and/or physical organic chemistry. Superior laboratory skills and proficiency in experimental design Familiarity with structure-activity and structure-property relationships Familiarity with modern drug discovery concepts such as MPO, tools such as SBDD, and analysis tools such as Spotfire Ability to multitask and work within timelines. Experienced and demonstrated success as primary author of publications, presentations, regulatory documents and/or primary inventor of patents. Demonstrated scientific communication and presentation skills by presenting at leading scientific conferences. Recognized and sought out as an expert in his/her discipline within the company and possibly externally. Key Leadership Competencies: Builds strong relationships with peers and cross functionally with partners outside of team to enable higher performance. Learns fast, grasps the "essence" and can change course quickly where indicated. Raises the bar and is never satisfied with the status quo. Creates a learning environment, open to suggestions and experimentation for improvement. Embraces the ideas of others, nurtures innovation and manages innovation to reality. Equal Opportunity Employer Minorities/Women/Veterans/Disabled
Feb 21, 2019
Full time
Pharmacyclics is committed to the development and commercialization of novel therapies intended to improve the quality and duration of life and to resolve serious unmet medical needs for cancer patients. Pharmacyclics is a wholly-owned subsidiary of AbbVie (NYSE:ABBV), a global, research-based biopharmaceutical company. Oncology is a key therapeutic area for AbbVie, with a portfolio consisting of three marketed products and a pipeline containing multiple promising new molecules that are being studied in more than 200 clinical trials for over 20 different types of cancer. More than 1,200 Pharmacyclics and AbbVie research scientists, clinicians, marketing, operations and corporate professionals work in the San Francisco Bay Area. They combine their expertise in immuno-oncology, stem cells, and cell-signaling with their knowledge of bispecific antibodies, antibody-drug conjugates (ADCs), and covalent-inhibitor technologies to discover and develop novel cancer treatments. Together, we are striving to outsmart cancer. To learn more about us, please visit us at Pharmacyclics is seeking a Senior Scientist III, Medicinal Chemistry. We are expanding a world-class medicinal chemistry team to drive innovation in small molecule oncology Discovery. You will work in a rapidly-growing organization, with the goal of identifying clinical candidates in the oncology field to address unmet medical needs. The ideal candidate should have a deep passion for drug discovery with a track-record of accomplishments as a synthetic chemist, demonstrate outstanding problem-solving skills, and curiosity to learn and develop as a medicinal chemist. Primary Job Function : Other than being an individual contributor of the medicinal chemistry team, direct research and/or project activities and professional development of a group of scientists within the individual's area of expertise by effectively mentoring, guiding and/or supervising scientific personnel. Expertise in synthetic organic chemistry and medicinal chemistry are essential for this position. By align with the project strategy, independently as well as influencing group members to conceive and communicate novel medicinal chemistry ideas, execute, drive the SAR optimization cycle to achieve project deliverables. Core Job Responsibilities : Maintain a high level of productivity in the laboratory setting by generating high impact compounds. Demonstrate the ability to resolve key project hurdles and assumptions by effectively utilizing available information and technical expertise. Seize opportunities to pursue project relevant leads that are in line with the group's strategy, and be responsible for developing new SAR/series. Effectively function as a principle investigator, generating original technical ideas and research or development strategies. Generate new scientific proposals and lead those efforts. Anticipate and critically evaluate scientific or regulatory advances or competitive threats and respond with appropriate new strategies. Demonstrate creative 'out of the box' thinking to solve difficult problems and champion new technologies to achieve project goals. Independently responsible for project science within his/her area of expertise on one or more project teams. Position Accountability/Scope : Demonstrate a high degree of responsibility in maintaining scientific standards, and safe laboratory practices. Participate in establishing project goals, defining short and long-term scientific strategies, and contribute to the generation of project-related documents and presentations. Keep accurate and current records of research and/or project related activities according to AbbVie policies. Internal/External Contacts and Interactions : Recognized and sought out as an expert in his/her discipline within the company and possibly externally. Use external information to gain competitive intelligence. Act as advocate to integrate this knowledge into the group's research efforts. Collaborate with functional and technical experts to facilitate scientific achievement. Recognized and sought out as an expert in his/her discipline within the company and possibly externally. Primary author of publications, presentations, regulatory documents and/or primary inventor of patents. Present at leading scientific conferences. Responsible for compliance with applicable Corporate and Divisional Policies and procedures. Qualifications: PhD in Organic/Medicinal Chemistry. Postdoctoral or pharmaceutical industry experience desirable; 6+(PhD with Postdoc) years of industrial experience Demonstrated ability to function as a principle investigator, generating original technical ideas and research or development strategies. Demonstrated creative 'out of the box' thinking to solve difficult technical problems and champion new technologies to achieve project goals. Experience in synthetic methods development, target-oriented synthesis, chemical biology, and/or physical organic chemistry. Superior laboratory skills and proficiency in experimental design Familiarity with structure-activity and structure-property relationships Familiarity with modern drug discovery concepts such as MPO, tools such as SBDD, and analysis tools such as Spotfire Ability to multitask and work within timelines. Experienced and demonstrated success as primary author of publications, presentations, regulatory documents and/or primary inventor of patents. Demonstrated scientific communication and presentation skills by presenting at leading scientific conferences. Recognized and sought out as an expert in his/her discipline within the company and possibly externally. Key Leadership Competencies: Builds strong relationships with peers and cross functionally with partners outside of team to enable higher performance. Learns fast, grasps the "essence" and can change course quickly where indicated. Raises the bar and is never satisfied with the status quo. Creates a learning environment, open to suggestions and experimentation for improvement. Embraces the ideas of others, nurtures innovation and manages innovation to reality. Equal Opportunity Employer Minorities/Women/Veterans/Disabled
Scientist - Computational Biologist in human genetics, pharmacogenetics and genomics The Translational Systems Biology Group within the Comparative Biology and Safety Sciences (CBSS) department at Amgen Cambridge is committed to bringing safe and transformative medicines to patients. Our mission is to apply a variety of human-centric approaches including human genetics along with cell, molecular, computational and structural biology techniques to develop methodologies that can assess the safety of our drug targets or elucidate mechanisms leading to toxicity. We are seeking a talented Scientist to join our Translational Systems Biology Group in Amgen Cambridge. We are particularly interested in candidates with a strong background in human genetics, pharmacogenetics and functional genomics. The successful candidate will play a hands-on role using a variety of computational tools to investigate the safety of potential therapeutics or target interventions. Key responsibilities Drive in silico efforts focused on using human genetics and functional genomic datasets to elucidate the biology of targets we are pursuing in order to inform the safety profile of our drug targets Perform large-scale analyses using multiple data types (e.g. pre-clinical data, drug side-effects, genetic variation, pharmacology) to support our predictive safety efforts Lead the design, execution, and interpretation of genetic studies to investigate the influence of genetic variants on drug response Define the overall strategy and goals for the application of human genetics/pharmacogenetics to drug safety assessment Initiate, design and establish internal and external collaborations in the area of human genetics to inform target selection, safety assessment and de-risking Mentor associates and postdoctoral fellows who lead genetic studies and projects, including wet lab molecular genetics experiments Interface directly with bioinformaticians and computational biologists to develop experimental plans and interpret genetic association studies Integrate other efforts within the group focused on human cell-based models and systems biology Collaborate with researchers and clinicians within Amgen to interpret nonclinical and clinical data Represent the Translational Systems Biology Group internally and externally through presentations, publications, networks, collaborations and conferences to promote the science of human genetics for safety assessment Basic Qualifications: Doctorate degree OR Master's degree and 4 years of scientific experience OR Bachelor's degree and 6 years of scientific experience Preferred Qualifications: PhD in computational biology, biostatistics, bioinformatics or a related field with 5+ years of human genetics or functional genomics experience Ability to design and lead human genetics studies (with a variety of study designs) delivering novel and actionable genetic findings relevant to drug development Expertise with multiple molecular genetic approaches including chip-typing, WES & WGS, Sanger, targeted sequencing, etc. as well as other functional genomic technologies (e.g. RNASeq, Single cell seq, and Proteomics etc.) Familiarity with statistical genetics and deep knowledge of statistical modeling, supervised and unsupervised learning Proficiency in computing languages such as R, Python, C/C++ and hands on experience in genetic and genomic data analysis Expertise in molecular characterization and functional studies geared towards elucidating the mechanistic basis for genetic associations Strong publication track record in top tier journals Comfortable working in a highly interactive and vibrant environment designed to promote frequent interaction and brainstorming Excellent leadership and communication skills and the ability to influence, inspire and lead the team into new scientific areas Our culture is what makes Amgen a special place to work. We have a powerful shared purpose around our mission - to serve patients. We respect one another, recognize contributions, and have embedded collaboration, trust, empowerment and inclusion in all that we do. Join Us If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen. Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients. Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status. .
Feb 21, 2019
Full time
Scientist - Computational Biologist in human genetics, pharmacogenetics and genomics The Translational Systems Biology Group within the Comparative Biology and Safety Sciences (CBSS) department at Amgen Cambridge is committed to bringing safe and transformative medicines to patients. Our mission is to apply a variety of human-centric approaches including human genetics along with cell, molecular, computational and structural biology techniques to develop methodologies that can assess the safety of our drug targets or elucidate mechanisms leading to toxicity. We are seeking a talented Scientist to join our Translational Systems Biology Group in Amgen Cambridge. We are particularly interested in candidates with a strong background in human genetics, pharmacogenetics and functional genomics. The successful candidate will play a hands-on role using a variety of computational tools to investigate the safety of potential therapeutics or target interventions. Key responsibilities Drive in silico efforts focused on using human genetics and functional genomic datasets to elucidate the biology of targets we are pursuing in order to inform the safety profile of our drug targets Perform large-scale analyses using multiple data types (e.g. pre-clinical data, drug side-effects, genetic variation, pharmacology) to support our predictive safety efforts Lead the design, execution, and interpretation of genetic studies to investigate the influence of genetic variants on drug response Define the overall strategy and goals for the application of human genetics/pharmacogenetics to drug safety assessment Initiate, design and establish internal and external collaborations in the area of human genetics to inform target selection, safety assessment and de-risking Mentor associates and postdoctoral fellows who lead genetic studies and projects, including wet lab molecular genetics experiments Interface directly with bioinformaticians and computational biologists to develop experimental plans and interpret genetic association studies Integrate other efforts within the group focused on human cell-based models and systems biology Collaborate with researchers and clinicians within Amgen to interpret nonclinical and clinical data Represent the Translational Systems Biology Group internally and externally through presentations, publications, networks, collaborations and conferences to promote the science of human genetics for safety assessment Basic Qualifications: Doctorate degree OR Master's degree and 4 years of scientific experience OR Bachelor's degree and 6 years of scientific experience Preferred Qualifications: PhD in computational biology, biostatistics, bioinformatics or a related field with 5+ years of human genetics or functional genomics experience Ability to design and lead human genetics studies (with a variety of study designs) delivering novel and actionable genetic findings relevant to drug development Expertise with multiple molecular genetic approaches including chip-typing, WES & WGS, Sanger, targeted sequencing, etc. as well as other functional genomic technologies (e.g. RNASeq, Single cell seq, and Proteomics etc.) Familiarity with statistical genetics and deep knowledge of statistical modeling, supervised and unsupervised learning Proficiency in computing languages such as R, Python, C/C++ and hands on experience in genetic and genomic data analysis Expertise in molecular characterization and functional studies geared towards elucidating the mechanistic basis for genetic associations Strong publication track record in top tier journals Comfortable working in a highly interactive and vibrant environment designed to promote frequent interaction and brainstorming Excellent leadership and communication skills and the ability to influence, inspire and lead the team into new scientific areas Our culture is what makes Amgen a special place to work. We have a powerful shared purpose around our mission - to serve patients. We respect one another, recognize contributions, and have embedded collaboration, trust, empowerment and inclusion in all that we do. Join Us If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen. Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients. Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status. .
Bristol-Myers Squibb Company
Redwood City, CA, USA
Associate Scientist - HTP Molecular Biology & Expression Job Description: We are seeking a skilled molecular biologist to join the high-throughput expression purification group to design, generate, and utilize expression constructs for protein expression in eukaryotic and prokaryotic expression systems. Specific Responsibilities: • General molecular biology involving isolation, manipulation, and characterization of DNA, RNA and proteins. • Design of mammalian cell expression vectors for recombinant proteins. • Mammalian cell culture and transfection using viral and lipid transfection systems. • Small-scale protein production using automation. • Perform experiments with strong attention to detail and documentation. • Excellent written and oral skills are necessary. • Accomplish goals under project team time lines. Requirements: • BS degree with 5+ years of relevant experience or MS degree with 2+ years of relevant experience and degree in Biochemistry, Molecular and Cell Biology, or similar field. • Demonstrated experience in design and construction of cell expression plasmid constructs, site-directed mutagenesis, and recombinant protein vector design. • Experience in expression of antibodies from small to medium scale is highly desirable. • Experience using automation (i.e. liquid handlers, etc.) and programming jobs on automation workstations is highly desirable. • Demonstrated independence in experimental design, execution, data analysis and troubleshooting is required. • Excellent interpersonal skills with the ability to interact effectively with teams is required.
Feb 21, 2019
Full time
Associate Scientist - HTP Molecular Biology & Expression Job Description: We are seeking a skilled molecular biologist to join the high-throughput expression purification group to design, generate, and utilize expression constructs for protein expression in eukaryotic and prokaryotic expression systems. Specific Responsibilities: • General molecular biology involving isolation, manipulation, and characterization of DNA, RNA and proteins. • Design of mammalian cell expression vectors for recombinant proteins. • Mammalian cell culture and transfection using viral and lipid transfection systems. • Small-scale protein production using automation. • Perform experiments with strong attention to detail and documentation. • Excellent written and oral skills are necessary. • Accomplish goals under project team time lines. Requirements: • BS degree with 5+ years of relevant experience or MS degree with 2+ years of relevant experience and degree in Biochemistry, Molecular and Cell Biology, or similar field. • Demonstrated experience in design and construction of cell expression plasmid constructs, site-directed mutagenesis, and recombinant protein vector design. • Experience in expression of antibodies from small to medium scale is highly desirable. • Experience using automation (i.e. liquid handlers, etc.) and programming jobs on automation workstations is highly desirable. • Demonstrated independence in experimental design, execution, data analysis and troubleshooting is required. • Excellent interpersonal skills with the ability to interact effectively with teams is required.
Bristol-Myers Squibb Company
Redwood City, CA, USA
We are looking for a highly motivated Senior Scientist to join the lead discovery effort within the biologics department in Redwood City, CA. This is an exciting opportunity to make a significant impact within a department that is driving biologics therapeutics at BMS. In this role the scientist is expected to develop, improve and champion a single B cell cloning platform to expand the delivery of high quality lead antibody molecules. Major responsibilities Contribute to the development and optimization of an existing single B cell platform within the Antibody Generation department. Expand the scope of application of single B cell and harmonize it with associated supporting platforms. Fully integrate the single B cell cloning protocol into lead generation pipelines. Be a champion in the lead discovery process and collaborate with therapeutic area leaders to progress project pipelines. Stay informed and contribute to the vision in the technology development space especially in immune cell biology and single cell analytics. Excellent written and oral skills are necessary Qualifications Ph.D. in immunology or related major with 4+ years industry experience. Hands on experience in FACS using BD and/or Sony systems is required. Target-centric Bcell sorting or selection experience is required. In-depth knowledge of B/T cell biology and humoral and cell mediated immune responses. Proficiency in cell biology techniques including cell culture is required Familiarity in molecular biology techniques including NGS is preferred. Past experience developing therapeutics against membrane targets including GPCRs is a plus. Highly innovative and self-motivated. Excellent time management and organizational skills. Demonstrated ability to work in a multidisciplinary biologics discovery team.
Feb 21, 2019
Full time
We are looking for a highly motivated Senior Scientist to join the lead discovery effort within the biologics department in Redwood City, CA. This is an exciting opportunity to make a significant impact within a department that is driving biologics therapeutics at BMS. In this role the scientist is expected to develop, improve and champion a single B cell cloning platform to expand the delivery of high quality lead antibody molecules. Major responsibilities Contribute to the development and optimization of an existing single B cell platform within the Antibody Generation department. Expand the scope of application of single B cell and harmonize it with associated supporting platforms. Fully integrate the single B cell cloning protocol into lead generation pipelines. Be a champion in the lead discovery process and collaborate with therapeutic area leaders to progress project pipelines. Stay informed and contribute to the vision in the technology development space especially in immune cell biology and single cell analytics. Excellent written and oral skills are necessary Qualifications Ph.D. in immunology or related major with 4+ years industry experience. Hands on experience in FACS using BD and/or Sony systems is required. Target-centric Bcell sorting or selection experience is required. In-depth knowledge of B/T cell biology and humoral and cell mediated immune responses. Proficiency in cell biology techniques including cell culture is required Familiarity in molecular biology techniques including NGS is preferred. Past experience developing therapeutics against membrane targets including GPCRs is a plus. Highly innovative and self-motivated. Excellent time management and organizational skills. Demonstrated ability to work in a multidisciplinary biologics discovery team.
Bristol-Myers Squibb is a global biopharmaceutical company whose mission is to discover, develop and deliver innovative medicines that help patients prevail over serious diseases. One shared journey is moving us forward at Bristol-Myers Squibb. Around the world, we are passionate about making an impact on the lives of patients with serious disease. Empowered to apply our individual talents and ideas so that we can learn and grow together. Driven to make a difference, from innovative research to hands-on community support. Bristol-Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees the resources to pursue their goals, both at work and in their personal lives. Position Overview : We seek an experienced, talented, highly motivated, and detail oriented Proteomics Researcher with established track record to join the Proteomics group within the Discovery Research and Translational Sciences organization at BMS. This is a laboratory based position, reports to the Head of Proteomics within the Genomics organization and is expected to work effectively in a highly collaborative matrixed environment. The candidate needs to have a good understanding of biology to help articulate the problem statement, communicate with key stakeholders and bridge across matrixed teams. The candidate should have demonstrated ability to convert datasets to usable knowledge and utilize it to support the program progression across the Drug Discovery to Development continuum. The candidate needs to have an established track record and significant experience in articulating the need for proteomics as well as successfully applying proteomics to translational, clinical discovery space. The candidate needs to have deep familiarity with other "omics" and experience in building synergies to achieve integrative omics outcomes. Deep experience developing, deploying and utilizing innovative proteomics techniques / workflows to characterize complex proteomes and thereby enable translational and clinical research activities is absolutely necessary. Deep experience with proteomics analytical instrumentation (latest generation, nano-chromatography and mass spectrometry) and associated data processing software interfaces is a must. Experience with proteome level post-translational modification analyses (e.g. glycosylation, acetylation/methylation) is highly desirable. Significant experience and in-depth knowledge of proteomics design of experiments, LC/MS proteomics data processing and subsequent data analyses. Detailed understanding of proteomics related bioinformatics and associated software packages is required. Experience and ability to successfully interface with bioinformaticians and biostatisticians is an absolute must to achieve in-depth proteomics data analysis and superlative outcomes for programs. Experience with automation and laboratory instrument data management would is highly desirable. Proficiency in applying classical protein biochemical techniques (protein fractionations, chromatography etc.) and most up to date proteomics techniques is expected and familiarity with basic cell culture techniques and standard molecular biology techniques is highly desirable. Additionally, experience with handling human as well as animal biomatrices (including tissues, plasma ...) is necessary. Overall, excellent lab skills and lab etiquette are crucial and required to be successful in this position. The candidate must have expertise with compiling and reviewing lab work practices and maintain regular scientific records in terms of laboratory notebooks. The candidate should be proficient with workplace software tools (word processing, excel, presentation etc.). Qualifications Ph.D. in Life Sciences, Biochemistry, Analytical Chemistry or related field is preferred including a minimum of 4 to 10 years of relevant proteomics experience. Scientific creativity, innovation and resilience are absolutely necessary to be successful in this position. A track record of scientific productivity in proteomics area documented in high impact peer reviewed journals is necessary. A demonstrated ability to manage teams and contribute strategically to areas discovery & translational research. The candidate should have a strong interest in translational, clinical and drug discovery research. The individual should possess ability to handle multiple projects in parallel, closely collaborate & matrix with scientists within the group and with investigators across Translational Medicine and Discovery organization. The candidate is required to have effective organization and presentation skills; be reliable, highly motivated, have strong interpersonal communication skills and embrace working in a team/matrix environment. Ability to effectively manage scientific staff by articulating a vision, prioritizing work and supervising studies is highly desirable. The candidate should possess strong personal attributes of integrity, perseverance in face of challenges, and ability to tackle highly complex challenges.
Feb 21, 2019
Full time
Bristol-Myers Squibb is a global biopharmaceutical company whose mission is to discover, develop and deliver innovative medicines that help patients prevail over serious diseases. One shared journey is moving us forward at Bristol-Myers Squibb. Around the world, we are passionate about making an impact on the lives of patients with serious disease. Empowered to apply our individual talents and ideas so that we can learn and grow together. Driven to make a difference, from innovative research to hands-on community support. Bristol-Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees the resources to pursue their goals, both at work and in their personal lives. Position Overview : We seek an experienced, talented, highly motivated, and detail oriented Proteomics Researcher with established track record to join the Proteomics group within the Discovery Research and Translational Sciences organization at BMS. This is a laboratory based position, reports to the Head of Proteomics within the Genomics organization and is expected to work effectively in a highly collaborative matrixed environment. The candidate needs to have a good understanding of biology to help articulate the problem statement, communicate with key stakeholders and bridge across matrixed teams. The candidate should have demonstrated ability to convert datasets to usable knowledge and utilize it to support the program progression across the Drug Discovery to Development continuum. The candidate needs to have an established track record and significant experience in articulating the need for proteomics as well as successfully applying proteomics to translational, clinical discovery space. The candidate needs to have deep familiarity with other "omics" and experience in building synergies to achieve integrative omics outcomes. Deep experience developing, deploying and utilizing innovative proteomics techniques / workflows to characterize complex proteomes and thereby enable translational and clinical research activities is absolutely necessary. Deep experience with proteomics analytical instrumentation (latest generation, nano-chromatography and mass spectrometry) and associated data processing software interfaces is a must. Experience with proteome level post-translational modification analyses (e.g. glycosylation, acetylation/methylation) is highly desirable. Significant experience and in-depth knowledge of proteomics design of experiments, LC/MS proteomics data processing and subsequent data analyses. Detailed understanding of proteomics related bioinformatics and associated software packages is required. Experience and ability to successfully interface with bioinformaticians and biostatisticians is an absolute must to achieve in-depth proteomics data analysis and superlative outcomes for programs. Experience with automation and laboratory instrument data management would is highly desirable. Proficiency in applying classical protein biochemical techniques (protein fractionations, chromatography etc.) and most up to date proteomics techniques is expected and familiarity with basic cell culture techniques and standard molecular biology techniques is highly desirable. Additionally, experience with handling human as well as animal biomatrices (including tissues, plasma ...) is necessary. Overall, excellent lab skills and lab etiquette are crucial and required to be successful in this position. The candidate must have expertise with compiling and reviewing lab work practices and maintain regular scientific records in terms of laboratory notebooks. The candidate should be proficient with workplace software tools (word processing, excel, presentation etc.). Qualifications Ph.D. in Life Sciences, Biochemistry, Analytical Chemistry or related field is preferred including a minimum of 4 to 10 years of relevant proteomics experience. Scientific creativity, innovation and resilience are absolutely necessary to be successful in this position. A track record of scientific productivity in proteomics area documented in high impact peer reviewed journals is necessary. A demonstrated ability to manage teams and contribute strategically to areas discovery & translational research. The candidate should have a strong interest in translational, clinical and drug discovery research. The individual should possess ability to handle multiple projects in parallel, closely collaborate & matrix with scientists within the group and with investigators across Translational Medicine and Discovery organization. The candidate is required to have effective organization and presentation skills; be reliable, highly motivated, have strong interpersonal communication skills and embrace working in a team/matrix environment. Ability to effectively manage scientific staff by articulating a vision, prioritizing work and supervising studies is highly desirable. The candidate should possess strong personal attributes of integrity, perseverance in face of challenges, and ability to tackle highly complex challenges.
The Amgen Biologics Optimization group is seeking a highly motivated Senior Associate Scientist to join the Protein Biochemistry team at our state-of-the-art research facility in Thousand Oaks, CA. The Biologics Optimization group is responsible for the optimization, production, assessment, and selection of large molecule therapeutic drug candidates. The Sr. Associate Scientist will be a part of a multidisciplinary team with capabilities in protein engineering, cloning, expression and purification of large molecule drug candidates. The Sr. Associate Scientist will apply their scientific expertise to assist in the identification and optimization of promising therapeutic candidates to treat serious illnesses and advance Amgen's mission to serve patients. Responsibilities: Apply protein biochemistry expertise to purify and analyze therapeutic drug candidates. Drive innovation through the development of novel processes that increase capabilities, speed, throughput and/or quality. Generate scientific data to support generation of publications, patents, or regulatory submissions; participate in internal and external scientific outreach. Basic Qualifications: Master's degree and 3 years of scientific experience OR Bachelor's degree and 5 years of experience Preferred Qualifications: Experience with protein purification, particularly biologic molecules Expertise with a variety of chromatography techniques, liquid chromatography instrumentation (FPLC) and software (Unicorn, ChromLab) Familiarity with protein analytical techniques (HPLC, MCE, etc...) and analysis software (Chromeleon, LabChip) Knowledge of high throughput purification and analytical techniques is a plus Ability to multi-task, work flexibly and efficiently in a cross-functional environment Strong communication and interpersonal skills Our culture is what makes Amgen a special place to work. We have a powerful shared purpose around our mission - to serve patients. We respect one another, recognize contributions, and have embedded collaboration, trust, empowerment and inclusion in all that we do. Join Us If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen. Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients. Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status. .
Feb 21, 2019
Full time
The Amgen Biologics Optimization group is seeking a highly motivated Senior Associate Scientist to join the Protein Biochemistry team at our state-of-the-art research facility in Thousand Oaks, CA. The Biologics Optimization group is responsible for the optimization, production, assessment, and selection of large molecule therapeutic drug candidates. The Sr. Associate Scientist will be a part of a multidisciplinary team with capabilities in protein engineering, cloning, expression and purification of large molecule drug candidates. The Sr. Associate Scientist will apply their scientific expertise to assist in the identification and optimization of promising therapeutic candidates to treat serious illnesses and advance Amgen's mission to serve patients. Responsibilities: Apply protein biochemistry expertise to purify and analyze therapeutic drug candidates. Drive innovation through the development of novel processes that increase capabilities, speed, throughput and/or quality. Generate scientific data to support generation of publications, patents, or regulatory submissions; participate in internal and external scientific outreach. Basic Qualifications: Master's degree and 3 years of scientific experience OR Bachelor's degree and 5 years of experience Preferred Qualifications: Experience with protein purification, particularly biologic molecules Expertise with a variety of chromatography techniques, liquid chromatography instrumentation (FPLC) and software (Unicorn, ChromLab) Familiarity with protein analytical techniques (HPLC, MCE, etc...) and analysis software (Chromeleon, LabChip) Knowledge of high throughput purification and analytical techniques is a plus Ability to multi-task, work flexibly and efficiently in a cross-functional environment Strong communication and interpersonal skills Our culture is what makes Amgen a special place to work. We have a powerful shared purpose around our mission - to serve patients. We respect one another, recognize contributions, and have embedded collaboration, trust, empowerment and inclusion in all that we do. Join Us If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen. Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients. Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status. .
For more than 140 years, Lilly has been dedicated to meeting the health care needs of people in the United States and around the world. We address these needs primarily by developing innovative medicines-investing a higher percentage of our sales in research and development than any other major pharmaceutical company. Responsibilities In 2015, Lilly opened a state of the art Innovation Center in Cambridge, Massachusetts to explore how next generation therapeutics, connected delivery solutions, and data analytics can improve patient health while reducing the clinical, psychosocial and economic burden that is systemic throughout healthcare today. Integration of Pharmaceutical Sciences and Delivery Device Innovation is a focal point of the site. Formulation scientists and device engineers collaborate to bring innovative and integrated solutions to drug product development and delivery challenges. We are seeking highly motivated professionals with a start-up mentality to join our new Innovation Center in Cambridge, Massachusetts, to explore, develop and prototype new and emerging formulation and drug delivery technologies. If you have an interest in exploring new frontiers in formulation and drug delivery and use interdisciplinary problem solving methods to create breakthrough solutions for patients, you should consider joining our diverse team. The primary responsibility for the scientist will be to conduct fundamental studies to understand protein interactions at high concentrations with novel excipients. You will be responsible for conducting studies to identify excipients that can mitigate issues with high viscosity and stability. You will explore other novel and innovative ways to reduce viscosity of high concentration biologics. Understanding of physical and chemical stability challenges in high concentration bioproduct formulations will be a critical area of focus. The responsibilities for this role will include: Explore novel avenues to reduce viscosity of high concentration biologics Explore interactions between excipients and proteins that can lead to reduction in viscosity and increase in stability Identify and/or synthesize model excipients that can be designed to disrupt high viscosity and other challenges at high concentration Based on knowledge gained, build model(s) that can predict viscosity of bioproducts using inputs such as molecule properties, surface charge and formulation variables. Understand the reasons for physical and chemical stability challenges for bioproducts at high concentration Keep abreast of relevant new technologies / capabilities and regulatory initiatives / requirements. Authoring of technical reports, research grants, and journal publications. 43944BR Basic Qualifications PhD in Pharmaceutical Chemistry, Physical chemistry, Pharmaceutical Sciences, Biophysics, Biomedical Engineering or Biochemistry Experience/ knowledge of biophysical, physical and chemical characterization of proteins Additional Skills/Preferences Basic understanding of insulins, peptides, proteins, degradation pathways, and general approaches for stabilization Able to independently contribute from the bench (design and execute studies to develop a formulation) Experience/ knowledge of parenteral formulations development for preclinical, clinical and commercial use (including lyophilized and solutions formulations). In depth understanding of protein chemistry, structure and conformation, as relates to chemical and physical stability of small and large molecules. Demonstrated technical / scientific leadership skills; applied to problem-solving Good oral and written communication skills Must be able to work productively in an interdisciplinary team environment Additional Information Lilly credits its exceptional employees for its successes, and knows the key to ongoing achievement lies in attracting and retaining the best people. A company rich in heritage, Lilly employs individuals, conducts research and markets products worldwide. By providing for the unmet needs of our customers through a continuous stream of innovation, we will outgrow all competitors. Lilly earns consistent and wide recognition for creating an exceptional work environment: Business Week magazine 50 Best Places To Launch A Career™ FORTUNE America's Most Admired Companies™ FORTUNE 50 Best Companies for Minorities™ Working Mother 100 Best Companies for Working Mothers™ Industry Week magazine 100 Best-Managed Companies™ Business Ethics magazine 100 Best Corporate Citizens™ Science magazine Best Companies for Scientists™ This position is not permanent. It is for a fixed duration of two years with potential to extend annually for up to 4 years. Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status
Feb 21, 2019
Full time
For more than 140 years, Lilly has been dedicated to meeting the health care needs of people in the United States and around the world. We address these needs primarily by developing innovative medicines-investing a higher percentage of our sales in research and development than any other major pharmaceutical company. Responsibilities In 2015, Lilly opened a state of the art Innovation Center in Cambridge, Massachusetts to explore how next generation therapeutics, connected delivery solutions, and data analytics can improve patient health while reducing the clinical, psychosocial and economic burden that is systemic throughout healthcare today. Integration of Pharmaceutical Sciences and Delivery Device Innovation is a focal point of the site. Formulation scientists and device engineers collaborate to bring innovative and integrated solutions to drug product development and delivery challenges. We are seeking highly motivated professionals with a start-up mentality to join our new Innovation Center in Cambridge, Massachusetts, to explore, develop and prototype new and emerging formulation and drug delivery technologies. If you have an interest in exploring new frontiers in formulation and drug delivery and use interdisciplinary problem solving methods to create breakthrough solutions for patients, you should consider joining our diverse team. The primary responsibility for the scientist will be to conduct fundamental studies to understand protein interactions at high concentrations with novel excipients. You will be responsible for conducting studies to identify excipients that can mitigate issues with high viscosity and stability. You will explore other novel and innovative ways to reduce viscosity of high concentration biologics. Understanding of physical and chemical stability challenges in high concentration bioproduct formulations will be a critical area of focus. The responsibilities for this role will include: Explore novel avenues to reduce viscosity of high concentration biologics Explore interactions between excipients and proteins that can lead to reduction in viscosity and increase in stability Identify and/or synthesize model excipients that can be designed to disrupt high viscosity and other challenges at high concentration Based on knowledge gained, build model(s) that can predict viscosity of bioproducts using inputs such as molecule properties, surface charge and formulation variables. Understand the reasons for physical and chemical stability challenges for bioproducts at high concentration Keep abreast of relevant new technologies / capabilities and regulatory initiatives / requirements. Authoring of technical reports, research grants, and journal publications. 43944BR Basic Qualifications PhD in Pharmaceutical Chemistry, Physical chemistry, Pharmaceutical Sciences, Biophysics, Biomedical Engineering or Biochemistry Experience/ knowledge of biophysical, physical and chemical characterization of proteins Additional Skills/Preferences Basic understanding of insulins, peptides, proteins, degradation pathways, and general approaches for stabilization Able to independently contribute from the bench (design and execute studies to develop a formulation) Experience/ knowledge of parenteral formulations development for preclinical, clinical and commercial use (including lyophilized and solutions formulations). In depth understanding of protein chemistry, structure and conformation, as relates to chemical and physical stability of small and large molecules. Demonstrated technical / scientific leadership skills; applied to problem-solving Good oral and written communication skills Must be able to work productively in an interdisciplinary team environment Additional Information Lilly credits its exceptional employees for its successes, and knows the key to ongoing achievement lies in attracting and retaining the best people. A company rich in heritage, Lilly employs individuals, conducts research and markets products worldwide. By providing for the unmet needs of our customers through a continuous stream of innovation, we will outgrow all competitors. Lilly earns consistent and wide recognition for creating an exceptional work environment: Business Week magazine 50 Best Places To Launch A Career™ FORTUNE America's Most Admired Companies™ FORTUNE 50 Best Companies for Minorities™ Working Mother 100 Best Companies for Working Mothers™ Industry Week magazine 100 Best-Managed Companies™ Business Ethics magazine 100 Best Corporate Citizens™ Science magazine Best Companies for Scientists™ This position is not permanent. It is for a fixed duration of two years with potential to extend annually for up to 4 years. Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status
Nucleo Life Sciences, LLC. is a pharmaceutical company located in San Rafael, CA that develops innovative therapies into commercially viable products through proven pharmaceutical development expertise and creative problem solving. Nucleo offers specialized Chemistry, Manufacturing, and Controls (CMC) services to strategic partners. We are looking for highly motivated and talented individuals to join our team to bring new drug candidates into clinical development. Summary: The successful laboratory technician candidate will be responsible for assisting senior level staff. The job function requires basic laboratory skills with handling laboratory reagents, working in a GMP environment, and inventory management. Responsibilities Include: Support laboratory staff by preparing chemical solutions, balance checks, cleaning of glassware and equipment Follow instructions and lab protocols provided by senior staff Assist in collecting data in a laboratory notebook and reporting to senior staff for data analysis and interpretation Organize and facilitate the collection, clean up, and disposal of chemical waste Maintain laboratory in a safe, clean, and orderly condition, which includes functional checks on safety equipment such as eyewash stations, showers, fire extinguishers and hoods Assure availability of supplies, materials, and equipment needed for laboratories to maintain good functioning of the laboratory and offices. Assist with operations activities including GMP line clearance, release of materials and receiving and shipping materials. Update and manage equipment inventory and logbooks Inspect and maintain equipment ensuring they are clean and in good operating condition Recognize and troubleshoot any equipment malfunctions and if needed, work with in-house personnel or outside vendors to repair equipment Ensure clean rooms and general facility is maintained in optimum conditions and in compliance with GMP requirements. Education and Experience: Successful completion of two years of college education Experience working hands on in a laboratory environment. Knowledge, Skills and Abilities: This is a highly collaborative environment where willingness and ability to communicate and work flexibly within a team is essential. Excellent speaking, writing, presentation, and presentation skills are required. Proficiency with Microsoft Word, Excel, and PowerPoint. Ability to multitask in technical responsibilities is desired. Candidate is self-motivated, has strong problem solving skills, and works well independently. Equal Opportunity Employer
Feb 21, 2019
Full time
Nucleo Life Sciences, LLC. is a pharmaceutical company located in San Rafael, CA that develops innovative therapies into commercially viable products through proven pharmaceutical development expertise and creative problem solving. Nucleo offers specialized Chemistry, Manufacturing, and Controls (CMC) services to strategic partners. We are looking for highly motivated and talented individuals to join our team to bring new drug candidates into clinical development. Summary: The successful laboratory technician candidate will be responsible for assisting senior level staff. The job function requires basic laboratory skills with handling laboratory reagents, working in a GMP environment, and inventory management. Responsibilities Include: Support laboratory staff by preparing chemical solutions, balance checks, cleaning of glassware and equipment Follow instructions and lab protocols provided by senior staff Assist in collecting data in a laboratory notebook and reporting to senior staff for data analysis and interpretation Organize and facilitate the collection, clean up, and disposal of chemical waste Maintain laboratory in a safe, clean, and orderly condition, which includes functional checks on safety equipment such as eyewash stations, showers, fire extinguishers and hoods Assure availability of supplies, materials, and equipment needed for laboratories to maintain good functioning of the laboratory and offices. Assist with operations activities including GMP line clearance, release of materials and receiving and shipping materials. Update and manage equipment inventory and logbooks Inspect and maintain equipment ensuring they are clean and in good operating condition Recognize and troubleshoot any equipment malfunctions and if needed, work with in-house personnel or outside vendors to repair equipment Ensure clean rooms and general facility is maintained in optimum conditions and in compliance with GMP requirements. Education and Experience: Successful completion of two years of college education Experience working hands on in a laboratory environment. Knowledge, Skills and Abilities: This is a highly collaborative environment where willingness and ability to communicate and work flexibly within a team is essential. Excellent speaking, writing, presentation, and presentation skills are required. Proficiency with Microsoft Word, Excel, and PowerPoint. Ability to multitask in technical responsibilities is desired. Candidate is self-motivated, has strong problem solving skills, and works well independently. Equal Opportunity Employer
Bristol-Myers Squibb Company
Redwood City, CA, USA
Summary We are looking for a motivated and energetic candidate to join the Transgenic Discovery team in Redwood City. This is a highly collaborative environment focused on the discovery of life-saving, biologics-based medicines. The candidate will be responsible for bridging in vivo mouse work with in vitro phenotyping and characterization of genetically modified mice in support of our antibody discovery platform and therapeutic program advancement. The position will also play a prominent role in cell line engineering projects in the antibody and therapeutic areas. Responsibilities Responsible for designing and troubleshooting new genotyping assays, tracking, and managing all genotyping performed off-site. Execute screening for new genetically modified mice and cell line development. Perform genotyping, report and present data to support the validation of new genotyping assays. Work interactively with drug discovery teams on-site to validate, characterize, and distribute mouse models that directly address drug discovery and program validation. Compile data supporting phenotypic characterization and evaluation of transgenic mouse portfolio. Collaborate on cell line development projects through engineering, screening, and validation of isogenic cell lines and in pooled screening applications. Independence in experiment design, execution, troubleshooting, data interpretation and literature search is required. Requirements A B.S. with a minimum of 5 years of experience, or an M.S. with a minimum of 1+ years of experience with a strong scientific knowledge and research experience in immunology/molecular biology is preferred. Must be well versed in mouse genetics, mouse breeding, and genotyping Strong molecular biology skills including experience in genotyping methods (PCR, RT-PCR, CNV assays, DNA gel analysis) are required. Working knowledge of in vitro gene expression (RT-PCR, qPCR, ddPCR or similar) and immunology assays (immunizations, ELISAs, FACS, Western blotting, SPR or similar). Knowledge of cell engineering technologies, siRNA/shRNA knockdown, CRISPR-mediated genome editing. Experience with multicolor flow cytometry and cell sorting including design, execution and analysis is strongly preferred. Competency in data organization, e-notebook and database usage are a must. Proficiency in scientific computer programs including Microsoft Excel, GraphPad Prism, Spotfire, FlowJo. Position requires ability to work independently and collaboratively across a dynamic scientific environment, therefore excellent communication skills, both written and verbal, and strong interpersonal skills are necessary.
Feb 21, 2019
Full time
Summary We are looking for a motivated and energetic candidate to join the Transgenic Discovery team in Redwood City. This is a highly collaborative environment focused on the discovery of life-saving, biologics-based medicines. The candidate will be responsible for bridging in vivo mouse work with in vitro phenotyping and characterization of genetically modified mice in support of our antibody discovery platform and therapeutic program advancement. The position will also play a prominent role in cell line engineering projects in the antibody and therapeutic areas. Responsibilities Responsible for designing and troubleshooting new genotyping assays, tracking, and managing all genotyping performed off-site. Execute screening for new genetically modified mice and cell line development. Perform genotyping, report and present data to support the validation of new genotyping assays. Work interactively with drug discovery teams on-site to validate, characterize, and distribute mouse models that directly address drug discovery and program validation. Compile data supporting phenotypic characterization and evaluation of transgenic mouse portfolio. Collaborate on cell line development projects through engineering, screening, and validation of isogenic cell lines and in pooled screening applications. Independence in experiment design, execution, troubleshooting, data interpretation and literature search is required. Requirements A B.S. with a minimum of 5 years of experience, or an M.S. with a minimum of 1+ years of experience with a strong scientific knowledge and research experience in immunology/molecular biology is preferred. Must be well versed in mouse genetics, mouse breeding, and genotyping Strong molecular biology skills including experience in genotyping methods (PCR, RT-PCR, CNV assays, DNA gel analysis) are required. Working knowledge of in vitro gene expression (RT-PCR, qPCR, ddPCR or similar) and immunology assays (immunizations, ELISAs, FACS, Western blotting, SPR or similar). Knowledge of cell engineering technologies, siRNA/shRNA knockdown, CRISPR-mediated genome editing. Experience with multicolor flow cytometry and cell sorting including design, execution and analysis is strongly preferred. Competency in data organization, e-notebook and database usage are a must. Proficiency in scientific computer programs including Microsoft Excel, GraphPad Prism, Spotfire, FlowJo. Position requires ability to work independently and collaboratively across a dynamic scientific environment, therefore excellent communication skills, both written and verbal, and strong interpersonal skills are necessary.
Mister Kleen Maintenance Company, Inc.
Chantilly, VA, USA
Our "Environmental Technicians" do more than just dusting and vacuuming-they are the front-line defense in keeping tenants safe and healthy by owning the process of cleaning and sanitizing for the indoor health of the government facilities we serve. As a certified Green Seal (GS-42) cleaning contractor, Mister Kleen uses cleaning methods and products with environmentally friendly ingredients and procedures which are designed to preserve human health and environmental quality. What distinguishes Mister Kleen from our competitors is that every one of our 500 employees believe our continued success is based on service excellence achieved by teamwork. Top performers in our company fully embrace our core values of showing up on time, working hard, doing what you say, finishing what you start, and saying please and thank you. Typical job duties include, but are not limited to the following: High and low dusting Floor care, including washing, vacuuming, dust mopping, sweeping, spray cleaning Cleaning bathrooms, including toilets and sinks Emptying waste containers and other trash Other cleaning assignments as needed to wow our customers Here's what we need from you: An active Top Secret (or higher) security clearance A commitment to arriving to work on time each and every day A commitment to safety policies, procedures, and practices Candidates with a "can do" service attitude who takes great pride in their work and doing what it takes to make the customer happy The following are a plus, but not required: Previous experience performing custodial work Knowledge of cleaning products and services Ability to operate floor and carpet machines In return, we offer the most competitive compensation package that includes the following: Competitive base hourly rate Medical, dental and vision insurance Company paid life insurance and short- and long-term disability coverage 401(k) with Company match About us: Mister Kleen is a leading provider of contract cleaning services to Commercial and High Security facilities since 1976. Our primary service area is the D.C. metro region. We also provide a variety of interior and exterior specialty services.
Feb 21, 2019
Full time
Our "Environmental Technicians" do more than just dusting and vacuuming-they are the front-line defense in keeping tenants safe and healthy by owning the process of cleaning and sanitizing for the indoor health of the government facilities we serve. As a certified Green Seal (GS-42) cleaning contractor, Mister Kleen uses cleaning methods and products with environmentally friendly ingredients and procedures which are designed to preserve human health and environmental quality. What distinguishes Mister Kleen from our competitors is that every one of our 500 employees believe our continued success is based on service excellence achieved by teamwork. Top performers in our company fully embrace our core values of showing up on time, working hard, doing what you say, finishing what you start, and saying please and thank you. Typical job duties include, but are not limited to the following: High and low dusting Floor care, including washing, vacuuming, dust mopping, sweeping, spray cleaning Cleaning bathrooms, including toilets and sinks Emptying waste containers and other trash Other cleaning assignments as needed to wow our customers Here's what we need from you: An active Top Secret (or higher) security clearance A commitment to arriving to work on time each and every day A commitment to safety policies, procedures, and practices Candidates with a "can do" service attitude who takes great pride in their work and doing what it takes to make the customer happy The following are a plus, but not required: Previous experience performing custodial work Knowledge of cleaning products and services Ability to operate floor and carpet machines In return, we offer the most competitive compensation package that includes the following: Competitive base hourly rate Medical, dental and vision insurance Company paid life insurance and short- and long-term disability coverage 401(k) with Company match About us: Mister Kleen is a leading provider of contract cleaning services to Commercial and High Security facilities since 1976. Our primary service area is the D.C. metro region. We also provide a variety of interior and exterior specialty services.
Mister Kleen Maintenance Company
Chantilly, VA, USA
Our "Environmental Technicians" do more than just dusting and vacuuming-they are the front-line defense in keeping tenants safe and healthy by owning the process of cleaning and sanitizing for the indoor health of the government facilities we serve. As a certified Green Seal (GS-42) cleaning contractor, Mister Kleen uses cleaning methods and products with environmentally friendly ingredients and procedures which are designed to preserve human health and environmental quality. What distinguishes Mister Kleen from our competitors is that every one of our 500 employees believes our continued success is based on service excellence achieved by teamwork. Top performers in our company fully embrace our core values of showing up on time, working hard, doing what you say, finishing what you start, and saying please and thank you. Typical job duties include, but are not limited to the following: High and low dusting Floor care, including washing, vacuuming, dust mopping, sweeping, spray cleaning Cleaning bathrooms, including toilets and sinks Emptying waste containers and other trash Other cleaning assignments as needed to wow our customers Here's what we need from you: An active Top Secret (or higher) security clearance A commitment to arriving to work on time each and every day A commitment to safety policies, procedures, and practices Candidates with a "can do" service attitude who takes great pride in their work and doing what it takes to make the customer happy The following are a plus, but not required: Previous experience performing custodial work Knowledge of cleaning products and services Ability to operate floor and carpet machines In return, we offer the most competitive compensation package that includes the following Competitive base hourly rate Medical, dental and vision insurance Company-paid life insurance and short- and long-term disability coverage 401(k) with Company match Company DescriptionMister Kleen is a leading provider of contract cleaning services to Commercial and High Security facilities since 1976. Our primary service area is the D.C. metro region. We also provide a variety of interior and exterior specialty services. Our "Cleaning Technicians" do more than just dusting and vacuuming-they own the process of making facilities sparkle. Every one of our 400+ employees believes our continued success is based on service excellence achieved by teamwork. Top performers in our company fully embrace our core values of showing up on time, working hard, doing what you say, finishing what you start, and saying please and thank you. Mister Kleen is an Equal Opportunity Employer that recruits and hires qualified candidates without regard to race, religion, sex, sexual orientation, gender identity, age, national origin, ancestry, citizenship, disability, or veteran status
Feb 21, 2019
Full time
Our "Environmental Technicians" do more than just dusting and vacuuming-they are the front-line defense in keeping tenants safe and healthy by owning the process of cleaning and sanitizing for the indoor health of the government facilities we serve. As a certified Green Seal (GS-42) cleaning contractor, Mister Kleen uses cleaning methods and products with environmentally friendly ingredients and procedures which are designed to preserve human health and environmental quality. What distinguishes Mister Kleen from our competitors is that every one of our 500 employees believes our continued success is based on service excellence achieved by teamwork. Top performers in our company fully embrace our core values of showing up on time, working hard, doing what you say, finishing what you start, and saying please and thank you. Typical job duties include, but are not limited to the following: High and low dusting Floor care, including washing, vacuuming, dust mopping, sweeping, spray cleaning Cleaning bathrooms, including toilets and sinks Emptying waste containers and other trash Other cleaning assignments as needed to wow our customers Here's what we need from you: An active Top Secret (or higher) security clearance A commitment to arriving to work on time each and every day A commitment to safety policies, procedures, and practices Candidates with a "can do" service attitude who takes great pride in their work and doing what it takes to make the customer happy The following are a plus, but not required: Previous experience performing custodial work Knowledge of cleaning products and services Ability to operate floor and carpet machines In return, we offer the most competitive compensation package that includes the following Competitive base hourly rate Medical, dental and vision insurance Company-paid life insurance and short- and long-term disability coverage 401(k) with Company match Company DescriptionMister Kleen is a leading provider of contract cleaning services to Commercial and High Security facilities since 1976. Our primary service area is the D.C. metro region. We also provide a variety of interior and exterior specialty services. Our "Cleaning Technicians" do more than just dusting and vacuuming-they own the process of making facilities sparkle. Every one of our 400+ employees believes our continued success is based on service excellence achieved by teamwork. Top performers in our company fully embrace our core values of showing up on time, working hard, doing what you say, finishing what you start, and saying please and thank you. Mister Kleen is an Equal Opportunity Employer that recruits and hires qualified candidates without regard to race, religion, sex, sexual orientation, gender identity, age, national origin, ancestry, citizenship, disability, or veteran status
At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our 39,000 employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world. Responsibilities Lilly's Small Molecule Design and Development (SMDD) organization is involved in key development activities for small molecules and medium synthetic peptide active pharmaceutical ingredients from pre-clinical phases through commercialization for drug substances and drug products. Our scientists develop key technical and business solutions across the portfolio using their deep technical expertise to speed testing of the clinical hypothesis and overall drug development. SMDD tackles this diversity of responsibilities by recognizing an even greater diversity of talents and cultures is necessary to deliver the next generation of life changing medicines to patients. Innovation and integration is at the heart of what SMDD does. Our new state of the art research facilities are even designed to promote it! Lilly is seeking outstanding candidates to work at the drug substance - drug product interface for pharmaceutical development in a Particle design and crystallization process development role. This role provides you an opportunity to work side by side with process development teams to deliver key information deliverables needed to advance drug development while enabling the next generation of product design by developing new technical solutions across the portfolio. You would be located in Indianapolis where research is conducted in a new, state of the art development facility which enables collaboration and innovation (opened in June 2018). At Lilly, innovation is a key differentiator and this next generation of product development is crucial to speed the delivery of life-changing medicines to patients. The Particle Design Laboratory (PDL) resides within Small Molecule Design and Development (SMDD) and serves as a core competency center for particle and crystallization process design. The responsibilities and opportunities for this role include: Define the physical properties of the API required for the drug product and design crystallization processes in order to fulfill the physical property and chemical purity requirements, and support process scale-up and technology transfer. Leverage / develop process analytical technology, continuous processing, mechanistic models and novel formulation platforms to develop well understood and robust processes capable of enhancing or tailor API physical properties. In addition to small molecule API's, work on new peptide crystallization and precipitation platforms and lead our development in this area. Provide leadership within teams: Serve as a member of integrated commercial team (ICT) responsible for the development and demonstration of new bulk chemical processes. Provide key process information to the larger CMC team enabling the team to devise physical property and impurity control strategies. Direct and mentor technicians and younger scientists to deliver the portfolio and capability projects. Publish original research externally, author internal technical documents and control strategies for new product registration applications. Engage in a highly collaborative work environment across the crystallization, material science, analytical and formulation development areas including collaboration with external academic researchers. Control API properties through a firm understanding of thermodynamics and kinetics and scale variables such as heat and mass transfer to deliver the desired crystal form, chemical purity, and physical properties. Design and execute laboratory experimentation in support of crystallization process design using manual and automated high and low throughput reactors and leverage models to support process development. 42869BR Basic Qualifications PhD in Chemical Engineering, Materials Science or related discipline or BS/MS with 7+ years of industry experience. Additional Skills/Preferences Utilization of chemical engineering fundamentals towards process design: understanding of heat and mass transfer, thermodynamics, crystallization and precipitation kinetics, solid-liquid separations, drying, particle size reduction techniques (milling), experimental design, mixing theory. Experience with modeling, especially utilization of solubility and process models (including population balance models) along with the use of models for optimization and risk assessment. Experience with materials science, formulation development, absorption modeling, and modeling how physical properties impact drug product performance and / or manufacturability (both mechanistic or multivariate data analysis). Experience with online and offline analytical techniques and PAT such as HPLC, GC, NMR, IR, Raman, FBRM and solid state characterization techniques such as XRPD, DSC, TGA, particle size and microscopy to guide process development. Scale-up experience of multiple products and or platforms with demonstrated understanding of scale-dependency. Knowledge of GMP quality systems. Good oral communication and documentation skills. Teamwork/Interpersonal skills and experience leading teams and formulating business strategies. Experience with data interpretation, including the application of chemometrics, multivariate modeling, or other data analysis tools. Additional Information Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.
Feb 21, 2019
Full time
At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our 39,000 employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world. Responsibilities Lilly's Small Molecule Design and Development (SMDD) organization is involved in key development activities for small molecules and medium synthetic peptide active pharmaceutical ingredients from pre-clinical phases through commercialization for drug substances and drug products. Our scientists develop key technical and business solutions across the portfolio using their deep technical expertise to speed testing of the clinical hypothesis and overall drug development. SMDD tackles this diversity of responsibilities by recognizing an even greater diversity of talents and cultures is necessary to deliver the next generation of life changing medicines to patients. Innovation and integration is at the heart of what SMDD does. Our new state of the art research facilities are even designed to promote it! Lilly is seeking outstanding candidates to work at the drug substance - drug product interface for pharmaceutical development in a Particle design and crystallization process development role. This role provides you an opportunity to work side by side with process development teams to deliver key information deliverables needed to advance drug development while enabling the next generation of product design by developing new technical solutions across the portfolio. You would be located in Indianapolis where research is conducted in a new, state of the art development facility which enables collaboration and innovation (opened in June 2018). At Lilly, innovation is a key differentiator and this next generation of product development is crucial to speed the delivery of life-changing medicines to patients. The Particle Design Laboratory (PDL) resides within Small Molecule Design and Development (SMDD) and serves as a core competency center for particle and crystallization process design. The responsibilities and opportunities for this role include: Define the physical properties of the API required for the drug product and design crystallization processes in order to fulfill the physical property and chemical purity requirements, and support process scale-up and technology transfer. Leverage / develop process analytical technology, continuous processing, mechanistic models and novel formulation platforms to develop well understood and robust processes capable of enhancing or tailor API physical properties. In addition to small molecule API's, work on new peptide crystallization and precipitation platforms and lead our development in this area. Provide leadership within teams: Serve as a member of integrated commercial team (ICT) responsible for the development and demonstration of new bulk chemical processes. Provide key process information to the larger CMC team enabling the team to devise physical property and impurity control strategies. Direct and mentor technicians and younger scientists to deliver the portfolio and capability projects. Publish original research externally, author internal technical documents and control strategies for new product registration applications. Engage in a highly collaborative work environment across the crystallization, material science, analytical and formulation development areas including collaboration with external academic researchers. Control API properties through a firm understanding of thermodynamics and kinetics and scale variables such as heat and mass transfer to deliver the desired crystal form, chemical purity, and physical properties. Design and execute laboratory experimentation in support of crystallization process design using manual and automated high and low throughput reactors and leverage models to support process development. 42869BR Basic Qualifications PhD in Chemical Engineering, Materials Science or related discipline or BS/MS with 7+ years of industry experience. Additional Skills/Preferences Utilization of chemical engineering fundamentals towards process design: understanding of heat and mass transfer, thermodynamics, crystallization and precipitation kinetics, solid-liquid separations, drying, particle size reduction techniques (milling), experimental design, mixing theory. Experience with modeling, especially utilization of solubility and process models (including population balance models) along with the use of models for optimization and risk assessment. Experience with materials science, formulation development, absorption modeling, and modeling how physical properties impact drug product performance and / or manufacturability (both mechanistic or multivariate data analysis). Experience with online and offline analytical techniques and PAT such as HPLC, GC, NMR, IR, Raman, FBRM and solid state characterization techniques such as XRPD, DSC, TGA, particle size and microscopy to guide process development. Scale-up experience of multiple products and or platforms with demonstrated understanding of scale-dependency. Knowledge of GMP quality systems. Good oral communication and documentation skills. Teamwork/Interpersonal skills and experience leading teams and formulating business strategies. Experience with data interpretation, including the application of chemometrics, multivariate modeling, or other data analysis tools. Additional Information Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.
Position Summary Service Technicians are vital to the uptime of our customers' worksite. Problem solvers, customer-focused, and team players, Service Technicians are the reason customers come to us with their machines. That's why 4Rivers Equipment is seeking qualified candidates for a full-time Service Technician at our Fort Collins location. This position satisfies customers' needs with each bolt they tighten or part they put on. Benefits Medical/Dental/Vision 401K Match Life/ADD Online Learning Paid Sick & Vacation Asset Investment Employee Discount Customized Career Path Company Summary By partnering with 4Rivers Equipment, you become part of a John Deere Award Winning team with over 400 employees in locations up and down the Front Range of the Rocky Mountains. From Wyoming, through Colorado and New Mexico, down to Texas, we work with customers as friends, and focus on getting the job done right. That's being, "Your Working Partner". 4Rivers Equipment is built with positive attitudes and partner-like integrity. We like to get the job done right for our customers, while keeping a fun and team-oriented work environment. Essential Duties: Pre-deliver, inspect, maintain, diagnose, and repair heavy equipment. Order parts and prepare repair estimates. Prepare accurate inspection and service reports and maintain other records as required. Complete jobs within 4Rivers Equipment's MST's and repair estimates. Keep work areas clean and orderly. Work in a safe manner. Comply with company policies and government regulations. Perform other duties as assigned. Education High School diploma or equivalent experience. Strong communication skills. Willingness to learn. Basic math skills. Self-motivated. Physical Demands Physical Effort: Service Technicians frequently stand for long periods of time, bend, lay, and crawl under to repair and service machines. They frequently lift parts and equipment weighing up to 50 pounds unassisted. They must be able to maneuver on/under heavy equipment and on agricultural/construction sites with irregular terrain. Service technicians must be able to operate a motor vehicle during both day and night as well. Working Conditions: Service Technicians work around hazards such as electrical, mechanical, and power equipment. They frequently have risk of exposure to chemicals, used oil, spent antifreeze, parts cleaning solvent, volatile hydrocarbons, battery acid, etc. There is often times adverse weather conditions that they must occasionally work in. There is often mists, fumes, dusts, and non-continuous noises of varying sound levels and intensities that regularly happen in the shop as well. Travel: Little to none. Regular and predictable attendance and punctuality is vital. Must attend work regularly and to arrive at work on time. Failure to do so detrimentally affects team morale and productivity. 4Rivers Equipment is an Equal Opportunity Employer. Full job description attached.
Feb 21, 2019
Full time
Position Summary Service Technicians are vital to the uptime of our customers' worksite. Problem solvers, customer-focused, and team players, Service Technicians are the reason customers come to us with their machines. That's why 4Rivers Equipment is seeking qualified candidates for a full-time Service Technician at our Fort Collins location. This position satisfies customers' needs with each bolt they tighten or part they put on. Benefits Medical/Dental/Vision 401K Match Life/ADD Online Learning Paid Sick & Vacation Asset Investment Employee Discount Customized Career Path Company Summary By partnering with 4Rivers Equipment, you become part of a John Deere Award Winning team with over 400 employees in locations up and down the Front Range of the Rocky Mountains. From Wyoming, through Colorado and New Mexico, down to Texas, we work with customers as friends, and focus on getting the job done right. That's being, "Your Working Partner". 4Rivers Equipment is built with positive attitudes and partner-like integrity. We like to get the job done right for our customers, while keeping a fun and team-oriented work environment. Essential Duties: Pre-deliver, inspect, maintain, diagnose, and repair heavy equipment. Order parts and prepare repair estimates. Prepare accurate inspection and service reports and maintain other records as required. Complete jobs within 4Rivers Equipment's MST's and repair estimates. Keep work areas clean and orderly. Work in a safe manner. Comply with company policies and government regulations. Perform other duties as assigned. Education High School diploma or equivalent experience. Strong communication skills. Willingness to learn. Basic math skills. Self-motivated. Physical Demands Physical Effort: Service Technicians frequently stand for long periods of time, bend, lay, and crawl under to repair and service machines. They frequently lift parts and equipment weighing up to 50 pounds unassisted. They must be able to maneuver on/under heavy equipment and on agricultural/construction sites with irregular terrain. Service technicians must be able to operate a motor vehicle during both day and night as well. Working Conditions: Service Technicians work around hazards such as electrical, mechanical, and power equipment. They frequently have risk of exposure to chemicals, used oil, spent antifreeze, parts cleaning solvent, volatile hydrocarbons, battery acid, etc. There is often times adverse weather conditions that they must occasionally work in. There is often mists, fumes, dusts, and non-continuous noises of varying sound levels and intensities that regularly happen in the shop as well. Travel: Little to none. Regular and predictable attendance and punctuality is vital. Must attend work regularly and to arrive at work on time. Failure to do so detrimentally affects team morale and productivity. 4Rivers Equipment is an Equal Opportunity Employer. Full job description attached.
Picture yourself working a shop with a bunch of talent surrounding you! Apprenticeship/mentor programs, hands on learning, tuition reimbursement, tool allowance. The ability to advance is there. As an Entry Level Service Technician at Broadway you will be part of a great team. You will work with and learn from our Quick Lane and Service Technicians in addition to our Shop Foreman, Service Advisors and Parts team members. As you develop your skills in the automotive field, you will be fulfilling the needs of our customers by ensuring their vehicle is safe for their family and serviced timely and right the first time. YOU: Have a passion for the automotive industry Work well with teammates and want to"act as a sponge" to learn Are interested in performing light vehicle maintenance; oil changes, flushes, tire rotations Want a career in this rapidly changing automotive world (…we will help you get there) Yes, we certainly need all of these too: Attention to detail Fast and efficient Mechanical aptitude Ability to work a few Saturdays Valid Driver's License At Broadway Enterprises, Inc., we take great steps to take care of our guests. We do the same for our Team Members. We offer a comprehensive benefits program to help protect the health and financial security of you and your family. Medical Plans--We offer 3 medical plans, 2 with annual company HSA match Dental Plan--Choice between two different dental plans Paid Time Off Paid Holidays Vision Plan--Annual eye exams and discounted eye wear 401(k) Retirement Plan with company match Company Paid Life Insurance FUN work environment Apply
Feb 21, 2019
Full time
Picture yourself working a shop with a bunch of talent surrounding you! Apprenticeship/mentor programs, hands on learning, tuition reimbursement, tool allowance. The ability to advance is there. As an Entry Level Service Technician at Broadway you will be part of a great team. You will work with and learn from our Quick Lane and Service Technicians in addition to our Shop Foreman, Service Advisors and Parts team members. As you develop your skills in the automotive field, you will be fulfilling the needs of our customers by ensuring their vehicle is safe for their family and serviced timely and right the first time. YOU: Have a passion for the automotive industry Work well with teammates and want to"act as a sponge" to learn Are interested in performing light vehicle maintenance; oil changes, flushes, tire rotations Want a career in this rapidly changing automotive world (…we will help you get there) Yes, we certainly need all of these too: Attention to detail Fast and efficient Mechanical aptitude Ability to work a few Saturdays Valid Driver's License At Broadway Enterprises, Inc., we take great steps to take care of our guests. We do the same for our Team Members. We offer a comprehensive benefits program to help protect the health and financial security of you and your family. Medical Plans--We offer 3 medical plans, 2 with annual company HSA match Dental Plan--Choice between two different dental plans Paid Time Off Paid Holidays Vision Plan--Annual eye exams and discounted eye wear 401(k) Retirement Plan with company match Company Paid Life Insurance FUN work environment Apply
Position Summary Service Technicians are vital to the uptime of our customers' worksite. Problem solvers, customer-focused, and team players, Service Technicians are the reason customers come to us with their machines. That's why 4Rivers Equipment is seeking qualified candidates for a full-time Service Technician at our Strasburg location. This position satisfies customers' needs with each bolt they tighten or part they put on. Benefits Medical/Dental/Vision 401K Match Life/ADD Online Learning Paid Sick & Vacation Asset Investment Employee Discount Customized Career Path Company Summary By partnering with 4Rivers Equipment, you become part of a John Deere Award Winning team with over 400 employees in locations up and down the Front Range of the Rocky Mountains. From Wyoming, through Colorado and New Mexico, down to Texas, we work with customers as friends, and focus on getting the job done right. That's being, "Your Working Partner". 4Rivers Equipment is built with positive attitudes and partner-like integrity. We like to get the job done right for our customers, while keeping a fun and team-oriented work environment. Essential Duties: Pre-deliver, inspect, maintain, diagnose, and repair heavy equipment. Order parts and prepare repair estimates. Prepare accurate inspection and service reports and maintain other records as required. Complete jobs within 4Rivers Equipment's MST's and repair estimates. Keep work areas clean and orderly. Work in a safe manner. Comply with company policies and government regulations. Perform other duties as assigned. Education High School diploma or equivalent experience. Strong communication skills. Willingness to learn. Basic math skills. Self-motivated. Physical Demands Physical Effort: Service Technicians frequently stand for long periods of time, bend, lay, and crawl under to repair and service machines. They frequently lift parts and equipment weighing up to 50 pounds unassisted. They must be able to maneuver on/under heavy equipment and on agricultural/construction sites with irregular terrain. Service technicians must be able to operate a motor vehicle during both day and night as well. Working Conditions: Service Technicians work around hazards such as electrical, mechanical, and power equipment. They frequently have risk of exposure to chemicals, used oil, spent antifreeze, parts cleaning solvent, volatile hydrocarbons, battery acid, etc. There is often times adverse weather conditions that they must occasionally work in. There is often mists, fumes, dusts, and non-continuous noises of varying sound levels and intensities that regularly happen in the shop as well. Travel: Little to none. Regular and predictable attendance and punctuality is vital. Must attend work regularly and to arrive at work on time. Failure to do so detrimentally affects team morale and productivity. 4Rivers Equipment is an Equal Opportunity Employer.
Feb 21, 2019
Full time
Position Summary Service Technicians are vital to the uptime of our customers' worksite. Problem solvers, customer-focused, and team players, Service Technicians are the reason customers come to us with their machines. That's why 4Rivers Equipment is seeking qualified candidates for a full-time Service Technician at our Strasburg location. This position satisfies customers' needs with each bolt they tighten or part they put on. Benefits Medical/Dental/Vision 401K Match Life/ADD Online Learning Paid Sick & Vacation Asset Investment Employee Discount Customized Career Path Company Summary By partnering with 4Rivers Equipment, you become part of a John Deere Award Winning team with over 400 employees in locations up and down the Front Range of the Rocky Mountains. From Wyoming, through Colorado and New Mexico, down to Texas, we work with customers as friends, and focus on getting the job done right. That's being, "Your Working Partner". 4Rivers Equipment is built with positive attitudes and partner-like integrity. We like to get the job done right for our customers, while keeping a fun and team-oriented work environment. Essential Duties: Pre-deliver, inspect, maintain, diagnose, and repair heavy equipment. Order parts and prepare repair estimates. Prepare accurate inspection and service reports and maintain other records as required. Complete jobs within 4Rivers Equipment's MST's and repair estimates. Keep work areas clean and orderly. Work in a safe manner. Comply with company policies and government regulations. Perform other duties as assigned. Education High School diploma or equivalent experience. Strong communication skills. Willingness to learn. Basic math skills. Self-motivated. Physical Demands Physical Effort: Service Technicians frequently stand for long periods of time, bend, lay, and crawl under to repair and service machines. They frequently lift parts and equipment weighing up to 50 pounds unassisted. They must be able to maneuver on/under heavy equipment and on agricultural/construction sites with irregular terrain. Service technicians must be able to operate a motor vehicle during both day and night as well. Working Conditions: Service Technicians work around hazards such as electrical, mechanical, and power equipment. They frequently have risk of exposure to chemicals, used oil, spent antifreeze, parts cleaning solvent, volatile hydrocarbons, battery acid, etc. There is often times adverse weather conditions that they must occasionally work in. There is often mists, fumes, dusts, and non-continuous noises of varying sound levels and intensities that regularly happen in the shop as well. Travel: Little to none. Regular and predictable attendance and punctuality is vital. Must attend work regularly and to arrive at work on time. Failure to do so detrimentally affects team morale and productivity. 4Rivers Equipment is an Equal Opportunity Employer.
Company Description New England Donor Services (NEDS) is seeking experienced, dedicated and enthusiastic people to join our team and become part of what the Boston Globe has recognized as a Top Place to Work in 2014, 2015, & 2016. Saving lives through organ and tissue donation is the mission uniting our employees and drives the work we do. Job Description The C entral Processing Coordinators responsibilities include receiving all of New England Donor Services (NEDS) deliveries, shipping of tissue to processors, ordering clinical supplies, shelving and rotating stock, keeping track of inventory levels for tissue and organ needs, packing organ and tissue recovery packs, cleaning and sterilization of instrument kits as well as cleaning of the clinical areas per NEDS standards. Some additional responsibilities include, but are not limited to: Maintains relationships with supply and repair vendors Arranges sharpening and repairing on an as-needed basis Restocks Tissue recovery supplies for external cases Cleans Kidney pumps for clinical readiness Arranges for the disposal of all NEDS medical waste Monitors all clinical equipment (freezers, autoclave, washers, refrigerators) and documenting appropriately when required Performs other duties as assigned Occasional travel may be required to satellite offices to perform Central Processing duties Qualifications Strong organizational skills and attention to detail required Basic computer skills in Word, Excel, Outlook, and ability to learn NEDSs internal systems including but not limited to True North. This position requires the ability to work weekends, mandatory overtime, and occasional travel to perform Central Processing Coordinator functions at NEDS satellite offices Additional Information When you join New England Donor Services you can expect competitive salaries and a great benefit package. Benefits include a generous Paid Time-off program, BCBS Health Insurance, BCBS Dental Insurance, Vision Insurance, 2x Annual Salary Life Insurance, Pet Insurance, Flexible Spending Account, Short-term Disability Coverage, Long-term Disability Coverage, 403b Retirement Contribution, Tuition Reimbursement, Employee Assistance Program and Discounts through Working Advantage. New England Donor Services is an equal opportunity employer and encourages diverse candidates to apply to meet the needs of the multicultural and multilingual communities we serve.
Feb 21, 2019
Full time
Company Description New England Donor Services (NEDS) is seeking experienced, dedicated and enthusiastic people to join our team and become part of what the Boston Globe has recognized as a Top Place to Work in 2014, 2015, & 2016. Saving lives through organ and tissue donation is the mission uniting our employees and drives the work we do. Job Description The C entral Processing Coordinators responsibilities include receiving all of New England Donor Services (NEDS) deliveries, shipping of tissue to processors, ordering clinical supplies, shelving and rotating stock, keeping track of inventory levels for tissue and organ needs, packing organ and tissue recovery packs, cleaning and sterilization of instrument kits as well as cleaning of the clinical areas per NEDS standards. Some additional responsibilities include, but are not limited to: Maintains relationships with supply and repair vendors Arranges sharpening and repairing on an as-needed basis Restocks Tissue recovery supplies for external cases Cleans Kidney pumps for clinical readiness Arranges for the disposal of all NEDS medical waste Monitors all clinical equipment (freezers, autoclave, washers, refrigerators) and documenting appropriately when required Performs other duties as assigned Occasional travel may be required to satellite offices to perform Central Processing duties Qualifications Strong organizational skills and attention to detail required Basic computer skills in Word, Excel, Outlook, and ability to learn NEDSs internal systems including but not limited to True North. This position requires the ability to work weekends, mandatory overtime, and occasional travel to perform Central Processing Coordinator functions at NEDS satellite offices Additional Information When you join New England Donor Services you can expect competitive salaries and a great benefit package. Benefits include a generous Paid Time-off program, BCBS Health Insurance, BCBS Dental Insurance, Vision Insurance, 2x Annual Salary Life Insurance, Pet Insurance, Flexible Spending Account, Short-term Disability Coverage, Long-term Disability Coverage, 403b Retirement Contribution, Tuition Reimbursement, Employee Assistance Program and Discounts through Working Advantage. New England Donor Services is an equal opportunity employer and encourages diverse candidates to apply to meet the needs of the multicultural and multilingual communities we serve.
SAN MARINO SECURITY SYSTEMS
San Marino, CA 91108, USA
JOB DESCRIPTION: Installing, servicing, and troubleshooting Security, Fire, ACCESS, and CCTV Systems in various homes and business throughout the San Gabriel Valley. Installer/Technician will serve as support to crew lead on installation team, communicate job status to the Operations Manager, and ensure the completion of installation. REQUIREMENTS: · Experience in Electronic Security (Security, Fire, ACCESS, CCTV), but willing to train the right candidate. · Must have high school diploma or GED required · Must be able to successfully pass a pre-employment criminal, background, and drug screening. · Must have a clean driving record (no DUI in the last 5 years) · Valid CA Driver's License · Electrical certification a plus · Must be able to lift 50 lbs · Ability to work in extreme environments (i.e., hot sun, cold, crawl spaces, attic, basements, etc.) · Must be willing and able to climb ladders, stairs, and on feet for long periods of time. · Must thrive in team environment RESPONSIBLITIES: · Pulling inventory for each installation job · Pre assemble job components in warehouse · Mounting hardware · Running various wires (CL2 Fire wire, CAT5 Wire, direct burial), may need to access attics and basements · Clean up of job site after installation · Practice safe work practices · Attend staff meetings WORK HOURS: 8 a.m. to 4:30 p.m. with overtime occasionally. Full time position. SALARY: Salary based on experience. Ranges from $15 to $28 per hour. START DATE: As soon as possible LOCATION: San Marino, CA BENEFITS: Regular 40 hour work week and paid vacation/sick time. Full benefits after 3 month probationary period (Medical, Dental, Aflac). 401 K Plan and Stock options after 1 year of employment. Interested Candidates should EMAIL or FAX their resume to Marci Donovan. Phone # Fax # . Email:
Feb 21, 2019
Full time
JOB DESCRIPTION: Installing, servicing, and troubleshooting Security, Fire, ACCESS, and CCTV Systems in various homes and business throughout the San Gabriel Valley. Installer/Technician will serve as support to crew lead on installation team, communicate job status to the Operations Manager, and ensure the completion of installation. REQUIREMENTS: · Experience in Electronic Security (Security, Fire, ACCESS, CCTV), but willing to train the right candidate. · Must have high school diploma or GED required · Must be able to successfully pass a pre-employment criminal, background, and drug screening. · Must have a clean driving record (no DUI in the last 5 years) · Valid CA Driver's License · Electrical certification a plus · Must be able to lift 50 lbs · Ability to work in extreme environments (i.e., hot sun, cold, crawl spaces, attic, basements, etc.) · Must be willing and able to climb ladders, stairs, and on feet for long periods of time. · Must thrive in team environment RESPONSIBLITIES: · Pulling inventory for each installation job · Pre assemble job components in warehouse · Mounting hardware · Running various wires (CL2 Fire wire, CAT5 Wire, direct burial), may need to access attics and basements · Clean up of job site after installation · Practice safe work practices · Attend staff meetings WORK HOURS: 8 a.m. to 4:30 p.m. with overtime occasionally. Full time position. SALARY: Salary based on experience. Ranges from $15 to $28 per hour. START DATE: As soon as possible LOCATION: San Marino, CA BENEFITS: Regular 40 hour work week and paid vacation/sick time. Full benefits after 3 month probationary period (Medical, Dental, Aflac). 401 K Plan and Stock options after 1 year of employment. Interested Candidates should EMAIL or FAX their resume to Marci Donovan. Phone # Fax # . Email:
Local Family Owned Automotive Repair facility, with locations in Goodyear and Surprise is seeking a professional, experienced, and knowledgeable automotive and/or Diesel technician to add to our team. The candidate must be able to diagnose and repair to specifications, including brakes and hydraulic systems, exhaust, primary and/or advanced fuel ignition and electrical, suspension and alignment. The ideal candidate will have a "can do" outlook, good problem-solving ability, have at-least 4 years hands on Automotive Technician experience, great customer service skills and valid Driver's License. We do specialize in Diesels, diesel knowledge is preferred but not required. Work schedule will be, Monday through Friday, competitive wages with unlimited earnings potential, pay rage between $20-$35/hour performance base pay DOE, a Company medical plan, and paid time Off (PTO). If you are looking for stability in a career, not just a job, and if you are a person who takes pride in their work, and wants to grow within a company than this may be the opportunity you've been looking for. All interested candidates please contact Josh at
Feb 21, 2019
Full time
Local Family Owned Automotive Repair facility, with locations in Goodyear and Surprise is seeking a professional, experienced, and knowledgeable automotive and/or Diesel technician to add to our team. The candidate must be able to diagnose and repair to specifications, including brakes and hydraulic systems, exhaust, primary and/or advanced fuel ignition and electrical, suspension and alignment. The ideal candidate will have a "can do" outlook, good problem-solving ability, have at-least 4 years hands on Automotive Technician experience, great customer service skills and valid Driver's License. We do specialize in Diesels, diesel knowledge is preferred but not required. Work schedule will be, Monday through Friday, competitive wages with unlimited earnings potential, pay rage between $20-$35/hour performance base pay DOE, a Company medical plan, and paid time Off (PTO). If you are looking for stability in a career, not just a job, and if you are a person who takes pride in their work, and wants to grow within a company than this may be the opportunity you've been looking for. All interested candidates please contact Josh at
