146 jobs found in Tarrytown

Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious diseases. Summary: The Protein Biochemistry organization, with staff located in Tarrytown, NY, provides biochemical and biophysical characterization of candidates in support of moving biotherapeutic drugs from late stage research through first-in-human studies. The director will manage a group within the protein biochemistry organization and be technically responsible for guiding and contributing to biophysical developability of lead candidates in research, development of analytical methods, and extended biochemical and biophysical characterization in support of IND filings. The candidate will also be responsible for managing the performance and career development of direct reports, serving on or leading cross-functional teams, writing and reviewing technical documents and regulatory submissions, developing analytical strategy, and communicating technical information to appropriate groups and management. Responsibilities: Essential Job Responsibilities • Together with protein biochemistry senior leadership team, provides high-level vision and strategy related to biotherapeutic characterization to ensure group is meeting industry standards and trends, management's expectations, while bringing an understanding of regulatory expectations. • Seeks and fosters existing and new collaborations with key cross-functional stakeholders that are aligned with senior management's expectations, and the group's responsibilities to support the drug development pipeline. • Supervises and mentors a group with accountability for individual performance management (i.e., setting goals and expectations, conducting performance reviews). • Ability to manage resources effectively to support the drug development pipeline with a focus on applying rigorous, high standards to the work, while consistently completing deliverables within program timelines and maximizing the potential impact of protein biochemistry deliverables on programs. Contributes to and reviews technical documents and regulatory documents. • Guides technical development of biochemical and biophysical assays. • Consistently provide clear written and verbal communication within protein biochemistry and with key cross-functional stakeholders. Participates and/or leads cross-functional development teams. Other Job Responsibilities • Guide characterization efforts to support initial toxicology studies. • Guide efforts to maximize operational effectiveness of the laboratory including continuous improvement in work practices, procedures, and employ compliance when appropriate. • Guide efforts to develop new cutting-edge technologies for improving efficiency or increasing depth of biochemical and biophysical characterization of biotherapeutic candidates. • Assist in transfer of methods to Regeneron's quality control group, or other groups, and external partners, when appropriate. • Ability to thoroughly analyze and understand methods, results, solves analytical problems, troubleshoots assays, and meets regulatory expectations for analytics. • Maintains effective communication with groups within protein biochemistry, R&D, industrial operations and product supply, and regulatory. • When appropriate and time permits, reviews and submits manuscripts for consideration for publication in peer-reviewed journals. Requirements: • Graduate degree (Ph.D.) or equivalent in biochemistry, biophysical chemistry, or related field with years of progressive industrial experience is required. • Excellent track record in supervising, mentoring, and developing direct and indirect reports with accountability for individual performance management is required. • Experience leading and informing teams and management, drafting and reviewing technical documents, and supporting CMC regulatory filings are required. • Excellent written and verbal communication skills and ability to work effectively in a cross-functional team environment are required. • High emotional intelligence is required. • Strong scientific background in protein analysis with hands-on laboratory experience in the biochemical or biophysical characterization of proteins is required. • Experience in developing analytical methods, characterizing proteins and other therapeutic modalities, and strong working knowledge of biochemical and biophysical characterization techniques are required. • Hands-on laboratory experience with liquid chromatography (FPLC, HPLC, and UPLC), static and dynamic light scattering, capillary and gel-based electrophoresis, spectroscopic techniques (fluorescence, CD, FTIR, Raman, DRS, SINS, SANS/SAXS), and in silico-based modeling are highly preferred. This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business. To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.

Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious diseases. Summary: Regeneron has grown very rapidly over the last 5 years. Not only have we grown over 500% --and now have close to 8000 employees -and commercially launched 4 new therapeutics, we have also been building the corporate functions and infrastructure that supports our Research, Development, IOPS and Commercial teams. The corporate functions have a foot print in the US, the UK and Dublin. Given the ongoing growth, key areas of HR support for this team include workforce planning, talent management, culture and employee engagement. Our corporate functions provide the right support to enable the outstanding innovation in research, the ability to develop over 20 products in the clinic, enable our production of high quality product for our patients and support our in-house and field commercial teams. The corporate (G&A) functions at REGN include areas such as Finance and Accounting, Legal, Corporate Communications, Strategic Sourcing and Procurement, Real Estate and Facilities, IT and HR. As Regeneron has grown and evolved, so has the HR function. We are on a several year journey and our on-going HR evolution is an investment in our own function -with a long term goal of HR having an even bigger impact on Regeneron's workforce & talent management practices and employee experience. We are investing in and implementing two foundational technologies (WorkDay and a centralized HR service center), creating an integrated Talent Management Center of Excellence and building our HR Business Partner capability to deliver more strategic HR support to our leaders. This HR role is a member of the G&A HR Business Partner team. This team supports 900+ employees and works collaboratively with each other and the HR Centers of Excellence (Talent Management, Total Rewards and HR Operations) to understand the strengths and the gaps across G&A and ensure HR can create programs and solutions that meet their business needs. HRBP's develop solutions to solve G&A business challenges in order to increase their ability to deliver on their everyday goal-supporting the teams that take Science to Medicine. You will be an advisor to executives, managers and employees on organizational and HR-related issues, including but not limited to workforce planning, talent acquisition and development, change management, organization design and effectiveness, employee engagement, employee relations, and performance management, to promote and maintain REGN's high-performance culture, the Regeneron Way. Key to this will also be your ability to quickly develop trusted relationships with people at all levels across G&A as well as within the HR team. You have to be comfortable with challenging the status quo in a growing team and be very comfortable with toggling back and forth between excellent tactical execution and making sure there is a sound and longer-term strategy behind all of our work and the solutions. The incumbent acts as a champion and a coach for the business, monitoring the effect of business decisions on people, and translating business needs to the HR COE's-and vice versa. Responsibilities: • Works with clients to help solve any people related issues, keeping in mind precedence and business needs. This includes partnering with internal HR experts (as needed) on employee relations, compensation, manager employee relations, leadership development, benefits, succession planning, employee development needs, etc. • Provides coaching to executives, managers and employees, with an emphasis on the helping the person understand what their options are for each situation and how demonstrating the Regeneron Way (our cultural values) can help drive their success. • Acts as the lead translator of business needs to the rest of the HR team to help shape company-wide HR systems and solutions. • A key focus will be on identification of key talent and developing a plan to either develop and or bring in those people to fill those talent gaps. Partners with Talent Acquisition and client groups to identify current and future talent needs. Clarifies the technical skills and behaviors that are critical for success. Participates in interviews for key positions (generally Assoc Dir and above), as well as the candidate debriefs. • Onboarding: Partners with hiring managers to support successful onboarding of new managers and leaders; may facilitate new leader ease-in sessions. • Learning & Organizational Development: Identifies needs (individual, team and department levels) within client areas and partners with L&OD to design solutions that will address business needs. Will be expected to be part of the design and delivery of the solution with L&OD. • Total Rewards: Partners with this team to define new roles, identify external comparable/market value of positions, implement annual pay for performance, market adjustments, and other reward and recognition programs, as well as developing, revising, and communicating career matrixes. • Employee Engagement: Uses Regeneron survey data results to help managers own and develop action plans that support their business and people needs. • HRBP team: Is an active contributor to an HRBP team that shares best practices and balance the needs of their own client group with the needs of the overall business. • Overall: Everything you do should directly support the capabilities of your client groups to meet their current and future business goals. #LI-LC1 Requirements: • Minimum of bachelor's degree in a scientific discipline or HR related discipline; advanced degree such as MBA, or Master's in Organization Development or Human Resources is preferred. • Minimum 10 years' experience in our industry: pharma/biopharma/biotech in an HR or management role. Experience supporting or working directly in a G&A organization is strongly preferred. • Must have experience working with senior management, technical leaders, and technical staff in the biotech/pharmaceutical sectors. Must know and understand the basics of the drug development business. • Must have expertise in talent acquisition and talent development within a technically driven organization. • Prior experience with Korn Ferry (previously Lominger) Leadership tools is a strongly preferred • Demonstrated track record of taking initiative, ability to get things done with a minimum of noise and the ability to prioritize the essential over the non-essential. • This role is both diagnostic and solution driven, so the ability to take a step back and do root cause analyses, and then using data to deliver pragmatic solutions are critical for success in this role. • Demonstrates a strong preference and ability for quantitative and qualitative data analysis, and be comfortable with a variety of technology, systems and data. This includes being agile with Microsoft Suite products, HRIS systems, and other people related systems (Korn Ferry/Lominger) • Must be learning agile and able to deal with ambiguity, and able to quickly translate complex people and data issues into clear and coherent solutions. • Must be able to actively negotiate and influence others, demonstrating courage and the ability to effectively push back on "that's the way we have always done it". Can identify the "third way" that can meet all party's needs. • Basic understanding of HR legal compliance requirements This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business. To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.

Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious diseases. Summary: The Cloud HPC Engineer will help build and maintain cloud and locally distributed processing environments for our Researchers and Business. You will "go deep" in our Research Computational platform services (HPC, Distributed Computational platform, Supercomputers), but be able to pitch in on the entire spectrum, and will also work with an application engineering team to ensure that that team is successful. As an engineer, you will report directly to the Director of Data Platform Services. You will develop and deliver configuration and deployment automation required for improving the functionality, availability, and manageability of our Research Computational Platform using AWS Cloud, Linux, Python or Ruby and configuration automation tools such as Ansible and Infrastructure Automation tools like Cloud Formation Scripts Responsibilities: • Develop and deliver configuration and deployment automation required for improving the functionality, availability, and manageability of our enterprise Research Computational Platform using Python or Ruby and configuration automation tools such as Puppet, Chef, or Ansible • Running and maintaining automated production infrastructure in AWS or other cloud provider • Migrating of HPC systems from data centers to cloud • Running container management systems (k8s, Mesosphere, ECS) in production • clear understanding of information security concepts and best practices • working knowledge and being able to troubleshoot networks: routing, subnets, ACLs, site-to-site tunnels • knowledge of agile/scrum processes • Good working knowledge managing Linux based Distributed systems • Good working knowledge in using HPC Schedulers like SGE, Slurm or Torque Requirements: • 2+ years IT experience in large, enterprise, multi-location data centers. • 2+ Year Solid AWS & DevOps Experience ( Must have ) • 1+ years' experience of HPC, Distributed Computational system build and support. • A Solid understanding of code and script (PHP, Python, Perl and/or Ruby) • Prior experience working in/ supporting product development or similar experience • Knowledge of distributed computing is a must have • Strong experience in Cloud automation Tool sets. • Deep experience with provisioning on the AWS cloud platform including EC2, S3, Auto scale, Security Groups and other related technologies • Expertise in continuous integration and continuous delivery concepts and practices • Able to write code in Python, JSON, YAML, or similar language as an application developer • Knowledge of best practices and experience with configuration management (puppet, salt, chef, Ansible, etc.) • Experience of running and maintaining automated CI/CD pipeline • Experience with dependency management and project configuration (maven, ant, composer, etc.)Knowledge of Cloud computing ( AWS preferred ) • Experience monitoring and designing solutions for the cloud • Experience with repository tools like Artifactory and Nexus • Experience using RESTful and web API services • Nice To Have: o knowledge of Continues Development & Automation (Dockers or Kubernetes, Prometheus, Open Tracing, Fluentd ) o Knowledge in AWS Parallel Cluster #LI-EG2 #dice This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business. To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.

Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious diseases. Summary: An R&D Associate performs a quality review of documentation that are routine in nature under the direct supervision of a supervisor/manager. Begin to independently make detailed observations, interpret and report findings per defined procedures to team members and management. May possess knowledge of the basic principles of GxP, industry practices and standards. Participates effectively as a member of a team. Responsibilities: • Under direct supervision, trains, learns and follows established procedures and protocols to perform a quality review of routine assignments. Reviews multiple documents within the same day. May multi-task across assignments. Routinely performs a high quality review. • Follow appropriate approaches or techniques to resolve findings, as directed. • Collects and assembles all available resources to perform a quality review. Learns to evaluate the quality of documentation. May identify potential mistakes/issues that may result in a process improvement. • Shares information in a clear and transparent manner, and effectively takes in information through strong listening skills. Takes direction and guidance from others in decision making. May participate in sub-group and/or department meetings and may share results of work with others. • Demonstrates problem solving skills within defined procedures and practices to determine appropriate action. Learns to comfortably shift gears and priorities to meet changing needs as required. • Executes necessary operations in LIMS as needed and utilizes the ELN for documentation and review purposes. • May provide cross functional support • Collaborates and engages others effectively while maintaining a productive working environment. • Is an avid learner who is open to feedback, learns from mistakes and participates in his/her own professional and personal development. Communicates effectively with management and team members. • Acts with integrity in all aspects of work and ensures ethical and professional conduct Educational Requirements: • 0 - 4 plus years of relevant experience for a Bachelor's degree • 0 - 2 plus year of relevant experience for a Master's degree Requirements: • Ligand binding assay experience including ELISA, MSD, Gyros in GLP environment and/or protein biochemistry experience such as ELISA, chromatography (HPLC, FPLC), electrophoresis (SDS-PAGE, CE, Westerns, IEE), Mass Spectrometry and static or dynamic light scattering techniques. • SoftMax Pro and Nautilus LIMS experience a plus. • Strong interpersonal and organization skills are required. • Computer proficiency including spreadsheets and databases is necessary; Strong knowledge of Word and Excel required. • Excellent communication skills (verbal and written). This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business. To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.

Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious diseases. The Corporate Strategy group at Regeneron is responsible for asking and answering questions critical to our business success. In this function we serve as an internal consultancy, conceiving and conducting analyses to inform decisions and understand their consequences. We work closely with senior leadership across all functions. The Senior Manager, Corporate Strategy will play an active role in all of these activities and will also have the freedom to create new ways to contribute toward achieving our company's mission. Responsibilities include but are not limited to: Develop models and analyses that address issues affecting the outlook of Regeneron and present them to senior management Work across all key areas of the company to gather information and data about our business Design and conduct interviews with functional groups to understand needs and problems, and help find solutions Identify major areas of strategic interest Build product revenue and expense inputs for Regeneron's long-term business outlook Contribute to the annual long-term outlook presentation for senior management and the Board of Directors Assist in communicating conclusions and recommendations of analyses across the organization Education Track record of academic excellence MBA or MD or PhD (equivalent work experience would be considered) Experience 2 years of experience in management consulting or corporate strategy OR A minimum of 4 years of experience in management consulting or corporate strategy for those without an advanced degree Must be skilled and experienced in commonly used business software including Excel and PowerPoint Command of analytical techniques, statistical reasoning and familiarity with data resources Enjoys collaborating and working across functions Adept at critiquing scientific and clinical information Familiarity with accounting, finance and valuation Excellent written and verbal communication skills Comfort working independently and as part of a group This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business. To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid. #LI-RE1 Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.

Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious diseases. Summary: The Global Development Process & Procedures (P&P) Operations Lead is directly responsible for driving the operations of the development and management of streamlined, procedural documents (Standard Operating Procedures (SOP), Work Instruction (WI), Guideline Document (GD), Job Aids, Forms and Templates) portfolio. Responsibilities: • Accountable for the delivery of quality procedural documents to functional areas/stakeholders • Oversee and manage the day-to-day operations of P&P Operation Managers to ensure adherence to standards and compliance for creating, updating and retiring procedural documents • Contribute to continuous improvements in standards (content and style) and procedural document templates in partnership with P&P Quality Lead • Analyze impact assessments for new and revised procedural document requests • Liaise with P&P Quality to ensure procedural document quality checks are performed in the agreed timeframe • Collaborate with P&P Quality Lead to identify trends in metric reports and provide recommendations for continuous improvements to further strengthen procedural document development methods • Maintain the master Global Development procedural document portfolio • Collaborate with P&P Business Partners for prioritization and forecasting workload • Manage and maintain electronic document management system (EDMS) including workflows, folder structure, etc. and interact with system owners as needed • Liaise with P&P Quality and oversee the preparation of documents for inspection requests (SOP lists, etc.) • Liaise with P&P Quality Lead to support internal Quality Auditing & Assurance Corrective Actions/Preventive Actions (CAPAs) that result in procedural document changes • Liaise with GCP Quality Improvement Representatives to identify trends for open process deviations Supervisory Responsibilities: • Manages several direct reports Requirements: BS/BA Degree with 10+ years relevant experience. MS degree and 8+ years relevant experience. • A minimum of 10 years' experience in a global regulated organization • A minimum of 8 years' experience in a quality role with experience in controlled procedural document principles, process design and styles, and leading process improvements • A minimum of 5 years' experience in Line Management including experience in mentoring and coaching direct reports • In-depth knowledge of GCP and regulatory requirements • Strong leadership with demonstrated ability to interact with all levels of the organization • Demonstrated success in managing teams and projects by maintaining a high level of productivity and quality work products • Demonstrated success in project management, stakeholder management, collaboration and negotiation of complex situations • Self-motivated with the ability to work effectively in a dynamic environment • Excellent problem solving, written and verbal communication skills • Negotiates complex situations without direct authority • Advanced technical skills: Word, Excel, Visio, electronic document management system • Ability to effectively manage multiple priorities with a sense of urgency • Provides close attention to detail and accuracy of work Core Behavioral Competencies: • Leadership • Executive Presence • Stakeholder Management • Project Management • Process Management • Line Management • Strategic Thinking • Critical Thinking & Problem Solving • Integrity and Trust • Negotiating • Organizational & Political Savvy • Dealing with ambiguity & paradox This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business. To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.

Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious diseases. Summary: The Sr. Director Global Study Strategy and Optimization will be responsible for the concept, design, growth and deliverables of the integrated Study Start Up, Global Trial Optimization, eClinical Outcomes Assessments and Patient Innovation functions to assure the highest quality support for delivery of Development Programs on time, with high quality and within budget. The incumbent will be instrumental in aligning, overseeing, and developing these functional areas to enable predictable delivery of clinical study milestones. This role is also responsible for management and oversight of multiple vendors who supply systems, services, and functional support. Included in the functional leadership scope are various trial support services including Study Start up sourcing and global infrastructure strategy and growth opportunities, feasibility, recruitment and retention, study planning and modeling, and site networking. The Sr. Director Global Study Strategy and Optimization is a member of the GCO senior leadership team, and as such interacts with senior level management, external vendors, collaboration partners and provides cross functional strategic direction and is accountable for building and managing teams across functions to identify risks and opportunities in Clinical Trial Execution and Innovative approaches to trial delivery. The incumbent will play a key role in developing and maintaining relationships with partner functions/activities such as; Vendor & Relationship Management, Clinical Study Contracts & Budgets, Regulatory/Ethics committee/IRB interactions, Clinical Drug Supply and Logistics, and Regulatory Compliance. Importantly, this role will have significant interface with Clinical Trial Management Leadership roles to ensure high quality support for trial execution. It will also be critical to ensure cross-program consistency of early program and study operational planning in support of study design decisions and downstream study execution and timelines. Responsible for leadership and development of functional group deliverables, management, and team/staff development. Responsibilities: • Leadership and oversight for functional group deliverables, management, and team/staff development • Oversee functional team responsible for program and study level feasibility strategy and processes • Provide leadership for CRO and team partnerships across study strategy • Oversee efforts to provide CTM teams recruitment support through internal and vendor efforts. • Oversee functional strategy for external engagement (i.e. patient, site,vendor and collaborations) • Lead and develop strategy for the development of a study start up team responsible for ensuring and overseeing the successful and on-time delivery of study start-up tasks and coordination including sourcing strategy and internal infrastructure management • Lead the functional team responsible for the definition, implementation, and management of electronic Clinical Outcomes Assessments (eCOA) across Global Development • Oversee strategy for development of Patient Innovation to ensure successful delivery of novel technologies and fit-for-purpose solutions to maximize trial effectiveness and reduce trial burden to the patient for Regeneron's clinical research portfolio. • Participate and provide input into a range of continuous improvement activities to ensure consistency of GCO process execution. • Drive the strategy for development and implementation of all direct report functions through process initiatives and change management activities. • Collaborate with Clinical Sourcing and Vendor & Relationship Management to provide functional input into the identification, qualification and relationship management of vendors utilized • Develop and maintain knowledge of external clinical trial environment and assess developments for impact on study design and execution. Identify and leverage external knowledge of industry best practices, processes and new trends • Oversee the Global Study Strategy and Optimization functions in accordance with company SOPs, FDA, & ICH guidelines and regulations. • Responsible for development of key metrics and dashboards to highlight trends and areas for continuous improvement or functional contribution deficiencies as well as provide updates to management. Requirements: Education • Bachelor's Degree • Advanced Degree Desirable Experience • 15+ years' of related industry experience • 15+ years of functional leadership • 10+ years people management Travel • Up to 30% Travel • Strong understanding and experience in operationalizing clinical development programs in a global setting from first-in-human to post-approval • Compelling communicator with ability to translate complex messages to a variety of audiences. • Proven ability to build strong working relationships in a diverse range of team environments • Experience in utilizing data to inform clinical strategy development • Ability to understand complex business questions and develop effective solutions • Experience in process development, implementation and change management activities • Thrives in a highly dynamic environment where creativity is key in meeting the needs of key stakeholders • Self - motivated, good interpersonal and leadership skills, a team player • Line management experience This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business. To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.

Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious diseases. Summary: VelocImmune (VI) Next is a technology development group at Regeneron that invents state-of-the-art tools for biologic drug discovery. We are seeking a motivated, accomplished researcher to investigate and help develop new antibody and cell-based therapies. This is an opportunity for a candidate with strong molecular & immunology skills to join a team developing industry-leading technologies and medicines. Responsibilities: • Conduct experiments, independently and collaboratively, investigating new technologies in antibody and T cell therapeutics. • Develop methods to express and characterize candidate therapeutic molecules from the VelocImmune pipeline in primary cells and cell lines, using Crispr/Cas9, gene targeting, viral vectors, flow cytometry, and immunologic assays. • Develop and perform molecular, cell-based, and immunologic assays to screen and prioritize candidate molecules. Experience with high-throughput assays is a major plus. • In vivo testing of experimental antibody and cell therapies, using tumor models in mice. • Contribute to the design and analysis of mice with modified immune loci and targeted gene humanizations for novel therapeutics discovery. • Evaluate mouse and cell-based models with NGS (next generation sequencing) and immune repertoire analyses. Experience with NGS data analysis and/or coding skills, especially in immunogenomics, strongly preferred. • Careful, thorough record keeping, data summarization, and presentation of results in formal and informal meetings. Requirements: • Strong skills in molecular biology and cloning, including vector construction, PCR, and extraction/analysis of DNA, RNA, and proteins. • Knowledge and experience with NGS methods is strongly preferred, including proficiency in Python, R, or other coding language. • Strong skills and experience in mammalian cell culture and manipulation is required, including transfection, stable line development, and viral vectors. Growing and manipulating primary cells is a major plus. • An established background in immunology, especially T and B cell biology. • Experience with multi-parameter flow cytometry is required. Experience and knowledge of immuno-assays (ELISA, Elispot, MSD, cytotoxicity, proliferation, etc.) strongly preferred. • Experience handling and manipulating mice. Knowledge of tumor models is a major plus. • An ability and desire to design experiments, problem-solve, and troubleshoot independently. Ideas and independent thinking are strongly encouraged. • Strong organizational, time-management, and presentation skills. • Minimum of Bachelors Degree with 5+ Years experience or MS with 2+ years experience in Molecular Biology, Biochemstry, Immunology, or relevant field. This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business. To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.

Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious diseases. Summary: We are seeking a highly motivated and experienced research associate to join the Muscle and Metabolism Group to support our discovery and development efforts pertaining to liver-related metabolic diseases. The individual will be responsible for the execution of in vitro and in vivo biological experiments necessary to develop cell-based and animal models for testing of experimental therapeutics and for mechanistic biology studies. The ideal candidate will have in-depth in vitro or in vivo technical expertise, be hardworking, flexible, innovative and able to function effectively in a fast-paced environment. They will also have excellent communication skills and be able to work well in a team. Responsibilities: • Strong in vitro and in vivo technical expertise is required. The ideal candidate will have expertise spanning both in vitro and in vivo techniques. • In vitro technical expertise including, but not limited to: Tissue culture, transfection, FACS, and in vitro cell-based assay development Western blotting, chromatography, immunoprecipitation, and ELISA development • Molecular biology including molecular cloning, mutagenesis, DNA/RNA isolation, qRT-PCR, CRISPR immunohistochemistry, immunofluorescence staining and in situ hybridization bright-field, fluorescent, and confocal microscopy and respective image analyses In vivo technical expertise including, but not limited to: • Mouse handling, injections (IP, SC, IV), bleeds (tail vein, retro-orbital, submandibular) oral and IP tolerance tests (glucose, insulin, lipid) • minor survival surgeries (ie osmotic pump implantation) major survival surgery experience is an asset • The candidate will also perform relevant data analysis and interpretation, collate data for presentation or reporting, and present data at group meetings. • The candidate will be responsible for maintaining accurate and complete laboratory records. Requirements: • BS/MS + 2+ years' experience • Strong in vitro and in vivo technical expertise is required. The ideal candidate will have expertise spanning both in vitro and in vivo techniques. • Proficiency in software for data analysis (e.g., DNA sequence alignment, Excel, Prism, FlowJo) and data reporting/presentation (e.g., Word, PowerPoint). • Ability to multi-task and perform work with a high degree of attention to detail. • Ability to troubleshoot and intepretate data independently. • Excellent oral and written communication skills. • Ability to collaborate productively with different functional groups. • Strong organizational and timely record-keeping skills. This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business. To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.

The Regeneron Genetics Center (RGC) is a wholly-owned subsidiary of the Company, whose goals are to apply large scale human genetics to identify new drug targets and to guide the development of therapeutics programs and precision medicine. Building upon Regeneron's strengths in mouse genetics and genetics-driven drug discovery and development, the RGC specializes in ultra-high-throughput exome sequencing, large scale informatics and data analysis encompassing genomics and electronic health records, and translating genetic discoveries into new biology and drug discovery opportunities. The RGC leverages multiple approaches including large population based studies, Mendelian genetics and family based studies, founder population genetics, and large-scale disease focused projects and has developed a network of over 50 collaborations with research organizations around the world. Including some of the largest sequencing studies in the world, such as the DiscovEHR study in collaboration with Geisinger Health System, and an initiative to sequence 500,000 participants with the UK Biobank, the RGC has built one of the largest human genetics databases, including sequence data from over several hundred thousand participants and rapidly growing. Our interests encompass a breadth of different areas across all therapeutic areas and the RGC is highly integrated into all facets of research and development at Regeneron. Program goals include target discovery, indication discovery, and patient-disease stratification. Objectives include advancing basic science around the world through public sharing of discoveries, providing clinically-valuable insights to physicians and providers of collaborating health-care systems, improving patient outcomes, and identifying novel targets for drug development. Summary: The RGC's Genome Informatics team leads the primary and secondary analysis of more than 500,000 samples a year, including production pipelines, cloud-compute infrastructure, and sequencing and variant quality control. Working closely with other RGC teams, our extensive genomics R&D portfolio supports multi-omics applications (RNA, long reads), unprecedented-scale variant calling, disease association studies, and loci-specific analyses that directly impact cutting-edge drug development. The Senior Production Engineer will lead the innovation, design and development of the RGC's production genomics compute infrastructure. Under the direction of the GI-Prod Director, this role will apply the latest hardware, software and cloud technologies to innovative solutions in genomics data structuring, distributed compute workflows, and unprecedented scale data manipulation and mining. Responsibilities: • Optimize production workflows and architecture • Working with GI-Prod leads, innovate ultra-large scale variant freeze process (QC and joint-genotyping) • Work closely with RGC Data Engineering to integrate production with distributed compute environment • Develop tools for GI-Prod and RGC users to facilitate at-scale, at-speed genomics (e.g. QC, variant calling, multi-omics) • Lead GI-Prod software development best practices (version control, code repositories) • Extend R&D work of GI-Prod to scalable, distributable software (CNV detection, RNA-seq) #LI-GP1 Requirements: • Bachelors in Computer Science or similar & 5+ years • Unix, Python (or similar) • Code repositories (GitHub, Sourceforge, Bitbucket) • Cloud Platform (AWS, GCP) • Standard bioinformatics tools (Samtools, BCFtools, VCFtools, BWA, GATK, Picard, BEDtools, PLINK) • Genomics data formats and analysis • Distributed compute platforms This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business. To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.

Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious diseases. Summary: Seeking a creative computational scientist to translate multiomics data into clinically relevant insights that advance our understanding of metabolic diseases. The scientist will create and apply novel methods to interpret and integrate across diverse data types, including from cutting-edge technologies developed internally. The successful applicant will have strong computational skills, an ability to clearly communicate with wet lab scientists and clinicians, and a desire to learn relevant disease biology and contribute to charting research direction. Responsibilities: • Collaborate with scientists in the Muscle & Metabolism group (among others) to design and interpret molecular profiling experiments. • Lead development of novel algorithms to analyze data generated by cutting-edge technologies including spatial transcriptome sequencing. • Run deep-dive analysis of transcriptomic, metabolomic, lipidomic, and other high-thoughput data. • Contribute to core functions of molecular profiling group including benchmarking algorithms, automating pipelines, and building visualization tools. • Present results to colleagues, senior management and collaborators. • Disseminate results in peer-reviewed journals and conferences. • Introduce novel research questions to drive our research forward. Requirements: The candidate will possess the following qualifications: • PhD + 5+ years experience • Strong scientific credentials in computational biology. • Expertise in machine learning algorithms, and in programming languages such as R, python, bash. • Experience analyzing at least some of: bulk RNA-Seq, single-cell RNA-seq, metabolomics, proteomics, lipidomics, and epigenetic data. • Strong communication skills. • Team orientation. Preferred job requirements • Knowledge of metabolic or muscle disorders • Familiarity with eQTL methods and interpretation • Experience with cloud computing, and in building databases and visualization tools. This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business. To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.

Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious diseases. Summary: The Oncology team is seeking a highly skilled Senior Research Specialist or Associate Scientist to perform complex in vivo preclinical imaging experiments to characterize and validate novel immune modulating anti-tumor therapeutics. The qualified candidate will have a strong background in immunology and/or oncology, flow cytometry, cell culture, and murine tumor models, with a willingness to learn preclinical imaging using fluorescence and/or radiation (PET or SPECT). The candidate must be highly motivated and organized with an attention to detail and should collaborate effectively with colleagues. We invite applications from individuals eager to use preclinical imaging techniques to support discovery and translational research. Responsibilities: • Develop therapeutic immuno-oncology tumor models in both immunocompetent and immunocompromised mice • Perform all aspects of longitudinal imaging studies, including planning, set-up, animal handling, dosing, scanner operation, and ex vivo biodistribution • Perform ex vivo processing/purification of multiple tissues/cells for subsequent immunohistochemistry and/or multi-parameter flow cytometry • Dose mice by intravenous, subcutaneous, and intraperitoneal injections, or oral gavage • Perform cell culture, including passaging, expanding, cryopreservation, thawing and processing of cells • Organize studies: timing of in vitro culturing, tumor implantation, and drug dosing • Summarize and record studies in electronic notebooks #LI-GP1 Requirements: This position requires a B.S./M.S. and at least 3-5 years'+ of experience Expertise in preclinical tumor models, administration of experimental drugs, and the ability to make detailed observations of tumor growth and mouse health Experience performing multi-parameter flow cytometry Experience or willingness to work with radioactivity Experience working with sterile cell culture techniques for the growth and maintenance of cell lines Strong organizational skills, including the ability to manage and record details of several projects simultaneously Candidate should be competent in standard scientific software used for data analysis (e.g., Microsoft Excel and Prism), as well as Microsoft Word and PowerPoint Candidate should be a strong team player with excellent oral and written communication skills and a demonstrated ability to work both independently and collaboratively, interpret data, and troubleshoot This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business. To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.

Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious diseases. Summary: Seeking a versatile computational scientist to support clinical and research programs in the metabolic disease space. Taking a lead role in these studies, the successful candidate will communicate effectively with researchers and clinicians, and develop methods to interpret diverse data types. Responsibilities: • Collaborate with scientists in the Metabolism and Muscle group, other Regeneron departments, and with external collaborators. • Analyze multiomic, clinical, and genetic data from patient cohorts. • Develop statistically robust tools for analyzing diverse data sets, from both established modalities and from novel technologies, e.g. spatial transcriptomics. • Provide scientific direction, technical expertise and coordinating activities with other groups at Regeneron. • Present results to colleagues, senior management and collaborators. • Disseminate results in peer-reviewed journals and conferences. • Introduce novel research questions to drive our research forward. #LI-GP1 Requirements: • PhD + 2 + Years' relevant experience • Demonstrated professional or academic achievement in computational biology. • Proficiency in programming languages such as R, python, bash. • Experience in analysis of bulk and single-cell RNA-seq, metabolomics, and proteomics data. • Knowledge of state-of-the art bioinformatics tools and approaches to support drug discovery programs. • Excellent communication skills. • Team orientation, creativity, and ability to juggle multiple projects. • Ability to work with a multi-disciplinary team encompassing both scientific and strategic perspectives. Preferred job requirements • Expertise in machine learning algorithms • Knowledge of metabolic or muscle disorders • Knowledge and experience in genetics and biostatistics This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business. To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.

Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious diseases. Summary: The Bioinformatics Data Engineer assists in the establishment, configuration, and maintenance of development environments running on the Amazon Web Services cloud and on-premise computing platforms. Furthermore, the candidate provides programming (specifically R & Python, but may include others) and infrastructural support for other bioinformatics developers across varied scientific disciplines. The position also oversees the onboarding of developers, communication of best practices and generation of usage reports. The post holder works closely with Research IT, IT-Cloud Services, scientists, and third parties to create compute environments and centralize research data repositories geared towards research activities. Responsibilities: • This role requires strong familiarity with the Linux environment, including extensive scripting (such as shell, R, Python) experience, configuring software, as well as supporting pipelines. • Provision and maintain data analytics platforms supporting our cutting-edge antibody discovery and production pipeline. • Provision and administer AWS resources (EC2, EBS, S3, RDS, etc). • Provide expertise in developing scientific applications and optimizing use of platform infrastructure Write software infrastructure to support pipelines and workflows. • Install, configure, maintain, and troubleshoot software applications. • Evaluate and implement new infrastructural paradigms (e.g. AWS Batch/Kubernetes). • Develop and maintain documentation and best practices for users of the scientific computing environment. • Assist in the preparation of reports and presentations. #LI-GP1 Requirements: • Strong background in R, Python, and shell scripting • Linux system administration • AWS cloud deployment experience • Familiarity with database management systems such as MySQL, MongoDB, Oracle, PostgreSQL • Experience with high performance and cloud based computing • Familiar with code version control systems such as git, subversion, CVS • Experience in scalable cloud-based platform architecture design • Code debugging, profiling and optimization techniques Preferred Skills: • Effective communication of complex concepts to collaborators with wide range of expertise. • Web server administration • Willingness to work in and adapt to a fast paced, changing environment Preferred Background: • Experience with molecular biology and genomics • MS in computer science, bioinformatics, computational biology, or related disciplines + 1 year experience • BS in computer science, bioinformatics, computational biology, or related disciplines + 3 years experience • 2+ years of AWS DevOps experience • AWS Associate certification • Previous experience in an industrial setting This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business. To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.

The Regeneron Genetics Center (RGC) is a wholly-owned subsidiary of the Company, whose goals are to apply large scale human genetics to identify new drug targets and to guide the development of therapeutics programs and precision medicine. Building upon Regeneron's strengths in mouse genetics and genetics-driven drug discovery and development, the RGC specializes in ultra-high-throughput exome sequencing, large scale informatics and data analysis encompassing genomics and electronic health records, and translating genetic discoveries into new biology and drug discovery opportunities. The RGC leverages multiple approaches including large population based studies, Mendelian genetics and family based studies, founder population genetics, and large-scale disease focused projects and has developed a network of over 50 collaborations with research organizations around the world. Including some of the largest sequencing studies in the world, such as the DiscovEHR study in collaboration with Geisinger Health System, and an initiative to sequence 500,000 participants with the UK Biobank, the RGC has built one of the largest human genetics databases, including sequence data from over several hundred thousand participants and rapidly growing. Our interests encompass a breadth of different areas across all therapeutic areas and the RGC is highly integrated into all facets of research and development at Regeneron. Program goals include target discovery, indication discovery, and patient-disease stratification. Objectives include advancing basic science around the world through public sharing of discoveries, providing clinically-valuable insights to physicians and providers of collaborating health-care systems, improving patient outcomes, and identifying novel targets for drug development. Summary: The RGC's Genome Informatics team leads the primary and secondary analysis of more than 500,000 samples a year, including production pipelines, cloud-compute infrastructure, and sequencing and variant quality control. Working closely with other RGC teams, our extensive genomics R&D portfolio supports multi-omics applications (RNA, long reads), unprecedented-scale variant calling, disease association studies, and loci-specific analyses that directly impact cutting-edge drug development. Under the direction of the QC lead, this entry-level role will support our efforts to develop, deploy and execute at-scale quality control protocols for both production and R&D experiments. Responsibilities: • Support all GI efforts to QC and analyze the world's largest genomic dataset • Preprare, validate and execute large-scale NGS analysis in cloud (AWS, GCP) and distributed compute infrastructure (SPARK) • Provide routine visualization of QC metrics, compute performance, and resource usage for RGC production • Support QC lead in validating production innovation • Create and develop in silico NGS standards and best practices • Work with GI leads to apply predictive models (e.g. machine learning) to QC metrics and analysis Requirements: • Bachelors in Computer Science or similar with minimum 1-3+ years relevant experience • Unix, Python • Visualization toolkit (R, Pandas) • Code repositories (GitHub, Sourceforge, Bitbucket) • Preferred: Standard bioinformatics tools (Samtools, BCFtools, VCFtools, BWA, GATK, Picard, BEDtools, PLINK) • Preferred: DNAnexus or other cloud experience This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business. To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.

Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious diseases. Summary: Protein Expression Sciences (PES) seeks an innovative PhD Scientist to develop new technologies to support Regeneron's antibody discovery pipeline. The technology development group is expanding efforts to develop high throughput methods and assays to better isolate and characterize antibody-derived fragments. This candidate would develop novel scaffolds for antibody expression, and advance new antibody isolation platforms and screening assays. Responsibilities: • Design and implement new methodologies to isolate antibodies from VelocImmune™ mice. • Design alternative antibody scaffolds and reformat variable regions. • Apply in-silico structure analysis to develop new antibody formats. • Develop mammalian cell-based platforms to screen for antibodies with unique binding abilities. • Collaborate with internal groups to develop high throughput assays to characterize antibody fragments for stability, affinity and antigen binding. • Actively communicate results and prepare presentations for departmental meetings. Requirements: • PhD in Biochemistry, Cell Biology, Immunology, Molecular Biology or related fields. • 3-5 years post-doctoral experience in antibody and/or protein engineering and expression. • Experience with library construction, and high throughput screening. • Expertise in one or more commonly used molecular modeling software packages, preferred. • Strong molecular biology skills and tissue culture experience. • Ability to work both independently and collaboratively in a team environment. • Excellent communication and presentation skills. This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business. To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.

Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious diseases. Summary Under direct supervision, provides routine husbandry care and maintenance of animals, including but not limited to feeding, watering, cage changing, and health checking of animals in the vivarium as well as maintenance of the facility. Responsibilities • Performs daily observations to check animals health status • Environmental monitoring with associated documentation • Changing and cleaning cages, equipment, water bottles, and food • Unpacking and housing animals upon arrival • Janitorial maintenance of facility rooms and stocking of supplies • Responsible for preventative maintenance of animal facility equipment and supplies • Monthly sanitization of equipment and the facility Requirements Education and Experience: HS Diploma or equivalent technical certificate. Pursuit of Purina and/or AALAS certification at the ALAT level is desired. (required after first year of employment) A minimum of one year experience in animal care is preferred for this position Work Environment: Position requires working closely with animals. Some noises may be associated with this position. Ability to lift 30 pounds required. The work environment characteristics described here are representative of those an employee encounters while performing the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions. Weekend and Holidays: This position is deemed essential personnel. Weekend and Holiday work is required. This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business. To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.

Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious diseases. Summary: Qualified physician or scientist with experience in the pharmaceutical/biotechnoloigy sector, or academic clinical setting. Works with supervisor and other members of the cross-functional study team to author/contribute to early clinical development protocols and facilitate execution of study activities and data summarization. Responsibilities: • Contributes to/leads the cross-functional study team on the following activities, including but not limited to: • Collaborates on/designs POC-enabling human studies, First-In-Human (FIH) studies, POC (clinical and/or pharmacologic) studies as per clinical strategy. • Responsible for the relevance and accuracy of medical science underpinning of clinical study based on thorough scientific review and consultation with internal and external experts. o Reviews, edits and finalizes clinical trial plans o Organizes and conducts consultations with global opinion leaders • Reviews and finalizes the medical and scientific portions of clinical study concepts (CSCs) and clinical study protocols (CSPs) and amendments. • Reviews and edits documents related to trials, such as monitoring plans, SAPs, amendments, IRB/IEC submissions and regulatory submissions. • Accountable, with input from Clinical Trial Management and Biostatistics and Data Management for timely clinical trial execution and quality of deliverables: o Leads and supervises the Clinical Team to produce high quality program deliverables on schedule o Identifies program, trial or data risks, creates and implements mitigation strategies o Maintains and develops relationship with key study investigators o Organizes clinical expert consultations, steering committees and data safety monitoring boards as required o Reports to supervisor and management on clinical trial findings and milestones o Responsible for the medical content of clinical study reports o Reviews all medical/scientific publications related to clinical trial • Analyzes the benefits and risk aspects of an assigned therapeutic candidate: o Responsible for the analysis of clinical data, including safety monitoring o Responsible for activities and procedures that ensure patient safety • Ensures Clinical Team compliance with FDA, EMEA, ICH and GCP guidelines as well as applicable SOPs regarding clinical safety. • Authors/contributes to clinical sections of communications/documentation for regulatory agencies and may participate in meetings as needed. • Conducts detailed literature reviews and analysis of development opportunities from mechanistic, pharmacological and clinical development perspectives. • Working with the ECD&ES Disease Area Lead, takes lead on various collaborations with TFA Research and Regeneron Genetic Center (RGC) colleagues to understand current and emerging targets/molecule program, provide clinical input on potential disease areas/indications, and design clinical experiments that corroborate or inform the biology for decision-making purposes. Requirements: Education: • M.D. degree. Board Certification/eligibility in a relevant therapeutic area preferred, along with relevant industry experience or clinical research/basic science research. Experience • 2-4 years prior industry experience or practice experience, preferably in a research/academic setting • Experience in analysis of clinical and basic research information from a wide range of topics. • Effective communications (verbal & written) and presentation skills are essential. • Must be able to work productively in a fast-paced collaborative environment. • Demonstrated critical thinking skills and sound decision-making SKC, #LI-SC1 This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business. To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.

Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious diseases. Summary: The Oncology and Angiogenesis research group is seeking a highly motivated Research Associate to assist with various aspects of cancer research. The ideal candidate has extensive experience in xenograft and orthotopic tumor models. More specifically, experience with injections, tumor cell implantation, tissue harvest, drug administration via various routes (iv, ip, sc), minor surgeries and necropsy, and cell culture (maintainance as well as cell based assays) is required. Additional experience with PDX models, evidence of technical expertise with in vivo imaging modalities, such as micro-ultrasound and bioluminescence imaging, is a plus. The candidate should be able to independently execute experiments and have excellent verbal and written communication skills. The ability to work effectively in a team, follow verbal and written instructions, good organizational and interpersonal skills, basic computer skills are a must. Responsibilities: • Tail vein, sc, ip, im injections • Tumor cell implantation, and monitoring of tumor growth and overall well-being of mice • Administration of different reagents in tumor bearing animals • Minor surgeries and necropsy • Tissue harvest • Tissue culture and basic-cell based assays • Assisting with micro-ultrasound and other in vivo imaging techniques • Data analysis and presentation • Interaction in cross functional teams • Meticulous record keeping • Efficient time management Requirements: This position requires a minimum of a BS/MS degree with 2-5 years of experience working with in vivo tumor models. Additional experience desired includes: - in vivo mouse experience - experience with various mouse tumor models including solid PDX - experience in tissue processing, sectioning and histology/IHC - outstanding organizational skils - good communication skills - efficiently work in a team - ability to independently follow verbal and written instructions - good interpersonal skills - basic skills with software packages This position will require a physical before starting This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business. To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.

Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious diseases. Summary: Under direct supervision, provides routine husbandry care and maintenance of animals, including but not limited to feeding, watering, cage changing, and health checking of animals in the vivarium as well as maintenance of the facility. Responsibilities: • Performs daily observations to check animals health status • Environmental monitoring with associated documentation • Changing and cleaning cages, equipment, water bottles, and food • Unpacking and housing animals upon arrival • Janitorial maintenance of facility rooms and stocking of supplies • Responsible for preventative maintenance of animal facility equipment and supplies • Monthly sanitization of equipment and the facility Performs basic care of research animals for experimental purposes: daily observations to check animal health status and environment; reports changes in environment and/or animals; changes and cleans cages, equipment, water bottles and food. Performs husbandry and maintenance duties; Conducts monthly sanitation of equipment and facilities. Maintains accurate records of animals, supplies, and equipment. Performs janitorial maintenance of facility rooms and stocks supplies. Performs preventative maintenance of animal facility equipment and supplies. Applies technical knowledge to perform the routine care and maintenance of research animals. Requirements: Education and Experience: HS Diploma or equivalent technical certificate. Pursuit of Purina and/or AALAS certification at the ALAT level is desired. (required after first year of employment) A minimum of one year experience in animal care is preferred for this position Work Environment: Position requires working closely with animals. Some noises may be associated with this position. Ability to lift 30 pounds required. The work environment characteristics described here are representative of those an employee encounters while performing the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions. Weekend and Holidays: This position is deemed essential personnel. Weekend and Holiday work is required. This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business. To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.