248 jobs found in Tarrytown

Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious diseases. Summary: Manipulates, observes and cares for genetically altered rodents to prepare them for study. Manipulations can include, breeding, weaning, identification markings, and collecting biopsies for RNA or DNA analysis. Records data pertaining to the above procedures in the Velocigene database. Some husbandry and general maintenance duties may be required. Responsibilities: Performs certain basic tasks necessary for the processing of genetically altered rodents such as animal identification by marking, breeding, weaning, and collection of tissue samples for DNA or RNA analysis. • Performs a natural history analysis when requested. • Records essential data in the Velocigene Data Management System. • Handles other responsibilities including, but not limited to, the breeding of rodents serving as embryo donors and recipients. • Performs husbandry (cage changing) duties. • Performs additional responsibilities related to the packing and shipping of rodents as well as some basic vivarium tasks such as ordering supplies, and general maintenance when needed. Requirements: • Previous work with the handling of laboratory rodents is preferred. The execution of above tasks will be guided by the Velocigene Data Management System and by instruction from the Vivarium manager. • Minimum of A.A. degree with some biology course work or a minimum of 2 years experience working with laboratory animals preferred. This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business. To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.

Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious diseases. Summary: Regeneron Pharmaceuticals Inc. is seeking a patent attorney at the Associate Director level to assist with the development of strategies for expanding Regeneron's intellectual property protection around key molecules, platforms and other technologies to ensure Regeneron's long-term competitive advantage. The patent attorney will also assist in providing IP transactional support in partnership with colleagues and clients in R&D, clinical, regulatory, legal, business and alliance management departments at Regeneron. Known for its scientific and operational excellence, Regeneron is a leading biotechnology company that invents life-transforming medicines for people with serious diseases. Founded and led for 30 years by physician-scientists, our unique ability to repeatedly and consistently translate science into medicine has led to seven FDA-approved treatments and numerous product candidates in development, all of which were homegrown in our laboratories. Our medicines and pipeline are designed to help patients with eye diseases, allergic and inflammatory diseases, cancer, cardiovascular and metabolic diseases, neuromuscular diseases, infectious diseases and rare diseases. Regeneron is accelerating and improving the traditional drug development process through our proprietary VelociSuite® technologies, such as VelocImmune® which produces optimized fully-human antibodies, and ambitious research initiatives such as the Regeneron Genetics Center, which is conducting one of the largest genetics sequencing efforts in the world. Responsibilities: • Conducting strategic IP due diligence, including the portfolios of competitors and potential collaborators; • Identifying opportunities for expanding Regeneron's IP position and working with members of various business, legal, scientific and administrative groups within Regeneron to take advantage of such opportunities; • Providing IP transactional support for a wide variety of business transactions, including research collaboration and licensing agreements, clinical agreements, master services agreements, clinical trial agreements, MTAs, consulting agreements, vendor agreements, and confidentiality agreements; and • Monitoring internal and external developments around key molecules, platforms and other technologies to provide IP strategic support for early stage collaborations after execution. Requirements: Education and Experience: • Juris Doctorate and admitted to practice in at least one state, New York preferred. • At least 4 years of top-tier IP law firm experience; additional in-house experience, a plus. • Ph.D. in life sciences field required, immunology a plus. • Registered to practice before the US Patent and Trademark Office. • Ideal candidate will have a broad range of patent-related legal expertise including patent preparation and prosecution, IP due diligence, litigation, licensing and strategic counseling. Essential Skills: • Exceptional communication skills, including presentation, interpersonal, writing and conflict resolution. • Ability to work collaboratively with colleagues and clients at all levels of the organization. • Ability to meet aggressive deadlines, handle multiple complex legal matters and see projects through to conclusion. • Strong knowledge of IP law required. • Experience working in biotech/pharmaceutical industry. • Experience with contracts involving intellectual property. • High level of business acumen. Supporting Statement: The IP Portfolio Development group within the Regeneron Law Department is focused on developing strategies to strengthen Regeneron's IP position through a deep understanding of Regeneron internal and relevant external molecules, platforms and technologies. In partnership with multiple groups within Regeneron, it identifies opportunities to enhance Regeneron's strategic IP position, advises internal clients to license or otherwise form strategic collaborations, facilitates execution of agreements and provides IP transactional support after execution. The current request is for a junior-level attorney to report to the Executive Director, Assistant General Counsel, IP Portfolio Development. This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business. To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law. #LI-PD1

Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious diseases. This position is in our Pharmaceutical Legal Operations department in Tarrytown, NY. We are looking for a Legal Intern who is interested in learning about how medicines are studied, developed and approved by Regulatory Authorities like the FDA. We are considering any law student who has just finished their first (1L) or second year (2L) in law school. The Legal Intern will support the Pharmaceutical Legal Operations and Corporate Compliance groups. Our Pharma Legal Ops team provides guidance and advice to departments including the Clinical, Medical, Market Access, and Sales and Marketing Teams responsible for strategies relating to commercial and medical activities for products that are in development and/or FDA-approved. The Corporate Compliance team is responsible for administering the company's compliance program, including the Anti-Bribery/Anti-Corruption (ABAC) compliance program across the company. The Legal Intern for our group will have exposure to a broad range of legal and corporate functions. The Legal Intern will assist Law Department attorneys to provide strategic counseling and ensure compliance with applicable laws related to clinical development and commercialization of the company's products, including: ICH GCP Guidelines; GDPR, HIPAA and other data privacy laws; Food, Drug and Cosmetic Act; False Claims Act; the Anti-Kickback Statue and similar state laws. The Legal Intern may assist in legal review of advertising and promotional materials, business plans/strategies, policies and SOPs, informed consent forms, and/or participate in compliance investigations and reviews. Start building your skills at Regeneron. • Must have completed a Bachelor's degree • Must be currently enrolled in accredited law school in the US and completed at least his/her first year. This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business. To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.

Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious diseases. This position is in Pre-Therapeutic Target Discovery within Bioinformatics Services Core in Tarrytown, NY. The Tier1 process at Regeneron analyzes gene function using a standardized set of phenotyping assays to study the effects of targeted mouse gene knockouts. This process is an early part of R&D to identify potential biological drug targets. The Regeneron Bioinformatics Core Service manages the organization, analysis and presentation of Tier1 data generated with a variety of technologies, such as automated serum chemistry and hematology instruments, fluorescence activated cell sorting (FACS), microcomputed tomography (uCT) and high-resolution episcopic microscopy (HREM) and RNASeq. Regeneron has accumulated more than a decade's worth of Tier1 data for nearly 1000 genes. The proposed project is to develop and implement a strategy for managing heterogenous data from many sources. The focus of this work is data infrastructure (eg databases, classification with ontologies, etc.) to support current and future data mining and meta-analyses . Start building your skills at Regeneron. • Must be a rising 3rd or 4th year undergraduate student, or a Masters student • Must be pursuing a degree in bioinformatics, biostatistics or equivalent disciplines • Experience with programming (unix shell, Python, R), databases and biostatics is required • Some background in life sciences would be helpful but is not required General Co-op Program Information: • Must be enrolled in, or accepted to, an academic program pursuing a Bachelor's, Master's, PhD or PharmD • Program is full-time (~40 hrs/wk) and is paid • Prefer demonstrated leadership in areas such as campus activities, clubs, sports or the community • Minimum GPA of 3.0 • You will work with a specific manager on a project(s) • Enjoy regular 1 hour Co-op Program events: learn about other areas of the company from employees, soft skills workshops, networking, volunteering, and more! • Present to your team on your project(s) Transportation and Housing: • A free shuttle is offered from the North White Plains or Tarrytown train stations to the Tarrytown campus • Get to know other incoming Interns on our closed LinkedIn page when you accept an offer This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business. To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.

Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious diseases. Summary: We are seeking a Ph.D. scientist with strong background in immunology to join the Bispecific Antibodies group. The position will support our ongoing efforts to design, produce and evaluate immunocytokines for immune-oncology indications. The successful candidate will work closely with a talented team of protein engineers and immunologists to characterize our novel therapeutics in preclinical in vitro/ex vivo experiments. Extensive knowledge and lab experience in multiparameter flow cytometry are required for this position. Additional expertise in molecular cloning or in vivo mouse tumor models is highly desirable. Responsibilities: • Independently design and execute complex multicolor flow cytometry (FACS) analysis on human and mouse immune cells, tumors, and cell lines. Conduct staining of both cell surface and intracellular antigens. Analyze data using FlowJo, Prism, Excel, etc. • Process tissue samples from mouse tumor studies (tumor, spleen, lymph node, blood, etc) for downstream FACS and ex vivo functional assays. • Perform in vitro/ex vivo functional assays (cell proliferation, cytotoxicity) and serum/supernatant analyte analysis (ELISA, MSD, CBA). • Independently conduct data analysis and troubleshooting. • Maintain complete, accurate, and timely record of experiments and data analysis. • Present data at group and inter-departmental meetings. • Collaborate within the Bispecific Antibodies group and with other functional groups at Regeneron. Requirements: • Ph.D. in Immunology, Oncology, Cell Biology or related fields. • Strong expertise in multi-color FACS analysis. • Experience in cell culture (primary cells and cell lines), tissue sample processing, and in vitro/ex vivo cell-based assays. • Experience in molecular cloning or mouse tumor models is highly desirable. • Excellent communication skills, ability to work productively in a fast-paced collaborative team environment. This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business. To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.

Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious diseases. The Molecular Profiling group is looking for a talented data scientist with experience in genomic data analysis and algorithm development. The scientist will analyze preclinical and clinical data to support target and biomarker discovery & validation, as well as develop statistical and computational methods to advance our understanding of complex biological systems. Develop computational methodologies to integrate and model multi-modal data to help address the gap in understanding new molecular biology. Work with leadership to identify novel therapeutic targets and biomarkers via mining proprietary pre-clinical and clinical data. Develop data analysis pipelines and establish data analysis best practices for emerging genomic technologies. Collaborate with colleagues in research to design experiments and define data analysis plans. Communicate results with collaborators, refine analysis based on feedback. Prepare clear, concise and easy-to-understand presentations and documentations for collaborators, senior management and government agencies. #LI-GP1 Requirements: PhD + 0-3 years minimum in computational biology, biomedical engineering, bioinformatics, applied mathematics, or related quantitative field, with a track record of high quality publications Experience in analysis, interpretation, and visualization of sequencing data (e.g. bulk/single-cell RNA-seq, CRISPR screening) Expertise in statistical data analysis and algorithm development High proficiency in analytical and programming tools such as Python and R, and their associated packages for statistics, modeling and visualization Hands-on experience in machine learning, predictive modeling, and/or image analysis is highly preferred Familiarity with Unix/Linux, shell scripting, SGE clusters, AWS environment Proven problem-solving skills and collaborative nature in fast-paced environment. Ability to work both independently and collaboratively Excellent communication and presentation skills This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business. To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law. #LI-GP1

Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious diseases. Summary: We are seeking a biophysical chemist to provide analytical protein characterization through the use of cutting-edge biophysical technologies in the Protein Biochemistry group at Regeneron. The qualified candidate will be responsible for providing in-depth biophysical and biochemical characterization of therapeutic proteins to support mid-late stage development programs. The candidate is expected to take on a leading role in applying a diverse array of advanced biophysical techniques to deepen our knowledge of late stage biotherapeutic proteins and their inherent heterogeneity to support regulatory application for commercialization. Responsibilities: -Independently designs and conducts protein biophysical and biochemical experiments; analyzes data to elucidate quality attributes of therapeutic protein candidates and/or products. -Provides biophysical support for both upstream and downstream functional groups; helps solve development problems in real-time. -Takes a leading role in late stage development efforts to characterize size/charge variants, protein-ligand complexes, and high concentration protein solutions of therapeutic protein drug candidates. -Documents experiments, results and findings in laboratory notebook; presents work at group and department meetings; contributes to drafting of analytical characterization reports, regulatory submission sections, and peer-reviewed articles for publication. -May serve as a team representative in drug candidate-specific development team meetings, and share knowledge and expertise of biophysical chemistry at cross-function team meetings. -May provide some assistance to Research Associates conducting research and developmental work. -Participates in the general lab and instrument maintenance. Educational Requirements: -PhD in biophysical chemistry, molecular biophysics, or biochemistry with 0-3 years post-doctoral training in analytical protein characterization; experience in or collaboration with the biopharmaceutical industry an advantage. Experience: -Demonstrated ability to apply a variety of biophysical techniques to study one or more of the following: protein-ligand complex formation, protein aggregation pathways, and/or analytical characterization of viral vectors (or related gene therapy products). -Demonstrated expertise in light scattering (static and/or dynamic) and spectroscopic (e.g. CD, fluorescence, and/or Raman) principles and applications for analysis of proteins; working knowledge of SPR and mass spectrometry a plus. -Extensive hands-on experience in performing and trouble-shooting size-based (e.g. SEC, CE-SDS, and/or AUC) and charge-based (e.g. icIEF, IEX) separation techniques. -Experience with analytical ultracentrifugation (AUC) and/or field flow fractionation highly desired. -Strong command of general protein folding, structure, and thermodynamics. -High degree of proficiency in a variety of computer software for acquiring and analyzing light scattering, capillary electrophoresis, spectroscopic, and chromatographic data (e.g. ASTRA, 32 Karat, Empower). -Excellent oral and written communication skills are required. -A passion for science and innovation with a strong commitment to continual improvement and making significant contributions in a team environment. This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business. To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.

Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious diseases. Summary: The Bioassay Group in the Therapeutic Proteins Department seeks a highly motivated and passionate Laboratory Manager to join a fast-paced, dynamic group involved in cell-based assay development and high-throughput screening. This role will be a critical part of the lab and serve as a lynchpin to keep the lab of 30+ research personnel running efficiently and effectively. The ideal candidate will be incredibly organized, have exceptional interpersonal communication skills, and a strong interest in both lab administration and science. The candidate should also possess prior laboratory research experience and/or laboratory management experience. The candidate will provide day to day lab operations support and serve as a key liaison between the scientific operations staff and instrument vendors, safety, facilities, IT, and CROs. There are opportunities to help support research projects as well. Responsibilities: Lab Operations: • Ordering/stocking/aliquoting general lab consumables/reagents • Coordinate/schedule/perform Instrument upkeep, Preventative maintenance, service repair calls, service contracts, software upgrades, IT issues, pipette calibrations, freezer/fridge maintenance, etc • Coordinate facilities requests i.e equipment moves, construction, personnel moves, new hire onboarding, etc • Ensure safety compliance, Coordinate safety audits and hazardous chemical inventory • Coordinate space planning, i.e bench, desk, and office assignments, storage management, laboratory organization, etc • Coordinate capital expenditure requests/orders Laboratory Liaison: • Serve as primary point of contact in laboratory for all administrative requirements • Acts as liaison with other Regeneron departments including the environmental health and safety office, facilities, information technology, etc • Serves as liaison with external vendors and CROs Research support: • Prep media for cell culture and screening • Cell scale up for screens • Cell and reagent prep and shipment to/coordination with CROs • Cell line engineering Requirements: 1. Bachelors with 2+ year's experience in basic research lab (familiarity with cell-based assays and/or managerial experience is a strong plus) 2. Human cell culture/tissue culture experience 3. Strong communicator 4. Ability to multi-task on several different projects 5. Excellent team player 6. Exceptional organization and record keeping skills This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business. #LI-EG2 #dice To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.

Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious diseases. Summary: The Sr. Director Global Study Strategy and Optimization will be responsible for the concept, design, growth and deliverables of the integrated Study Start Up, Global Trial Optimization, eClinical Outcomes Assessments and Patient Innovation functions to assure the highest quality support for delivery of Development Programs on time, with high quality and within budget. The incumbent will be instrumental in aligning, overseeing, and developing these functional areas to enable predictable delivery of clinical study milestones. This role is also responsible for management and oversight of multiple vendors who supply systems, services, and functional support. Included in the functional leadership scope are various trial support services including Study Start up sourcing and global infrastructure strategy and growth opportunities, feasibility, recruitment and retention, study planning and modeling, and site networking. The Sr. Director Global Study Strategy and Optimization is a member of the GCO senior leadership team, and as such interacts with senior level management, external vendors, collaboration partners and provides cross functional strategic direction and is accountable for building and managing teams across functions to identify risks and opportunities in Clinical Trial Execution and Innovative approaches to trial delivery. The incumbent will play a key role in developing and maintaining relationships with partner functions/activities such as; Vendor & Relationship Management, Clinical Study Contracts & Budgets, Regulatory/Ethics committee/IRB interactions, Clinical Drug Supply and Logistics, and Regulatory Compliance. Importantly, this role will have significant interface with Clinical Trial Management Leadership roles to ensure high quality support for trial execution. It will also be critical to ensure cross-program consistency of early program and study operational planning in support of study design decisions and downstream study execution and timelines. Responsible for leadership and development of functional group deliverables, management, and team/staff development. Responsibilities: • Leadership and oversight for functional group deliverables, management, and team/staff development • Oversee functional team responsible for program and study level feasibility strategy and processes • Provide leadership for CRO and team partnerships across study strategy • Oversee efforts to provide CTM teams recruitment support through internal and vendor efforts. • Oversee functional strategy for external engagement (i.e. patient, site,vendor and collaborations) • Lead and develop strategy for the development of a study start up team responsible for ensuring and overseeing the successful and on-time delivery of study start-up tasks and coordination including sourcing strategy and internal infrastructure management • Lead the functional team responsible for the definition, implementation, and management of electronic Clinical Outcomes Assessments (eCOA) across Global Development • Oversee strategy for development of Patient Innovation to ensure successful delivery of novel technologies and fit-for-purpose solutions to maximize trial effectiveness and reduce trial burden to the patient for Regeneron's clinical research portfolio. • Participate and provide input into a range of continuous improvement activities to ensure consistency of GCO process execution. • Drive the strategy for development and implementation of all direct report functions through process initiatives and change management activities. • Collaborate with Clinical Sourcing and Vendor & Relationship Management to provide functional input into the identification, qualification and relationship management of vendors utilized • Develop and maintain knowledge of external clinical trial environment and assess developments for impact on study design and execution. Identify and leverage external knowledge of industry best practices, processes and new trends • Oversee the Global Study Strategy and Optimization functions in accordance with company SOPs, FDA, & ICH guidelines and regulations. • Responsible for development of key metrics and dashboards to highlight trends and areas for continuous improvement or functional contribution deficiencies as well as provide updates to management. Requirements: Education • Bachelor's Degree • Advanced Degree Desirable Experience • 15+ years' of related industry experience • 15+ years of functional leadership • 10+ years people management Travel • Up to 30% Travel • Strong understanding and experience in operationalizing clinical development programs in a global setting from first-in-human to post-approval • Compelling communicator with ability to translate complex messages to a variety of audiences. • Proven ability to build strong working relationships in a diverse range of team environments • Experience in utilizing data to inform clinical strategy development • Ability to understand complex business questions and develop effective solutions • Experience in process development, implementation and change management activities • Thrives in a highly dynamic environment where creativity is key in meeting the needs of key stakeholders • Self - motivated, good interpersonal and leadership skills, a team player • Line management experience This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business. To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.

Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious diseases. Summary Position Summary: We are looking for a Sr. Animal Care Technician (ACT). Under general supervision, the Sr. ACT assists Vivarium Management in maintaining the operations of the facility and performing animal care procedures. This person begins mentoring technicians while demonstrating exemplary competencies and behaviors and is knowledge of applicable regulations regarding proper standards of animal care and use in a research environment required. General understanding of "The Guide". Excellent communication skills required. Responsibilities: • Performs basic care of research animals for experimental purposes: daily observations to check animal health status and environment; reports changes in environment and/or animals; changes and cleans cages, equipment, water bottles and food • Unpacking and housing animals upon arrival • Performs husbandry and maintenance duties; Conducts monthly sanitation of equipment and facilities. • Maintain accurate inventories and record of animals, supplies and equipment. Provides records as necessary to Vivarium Management. • Provides guidance to Animal Care Technicians. May assist in training new hires regarding facility procedures and practices. Assists Vet Services, as needed. Able to work with semi-rigid isolators and/or the specialized facility equipment. Requirements Education and Experience: HS Diploma or equivalent technical certificate. A minimum four years of experience working with animals in a research environment and AALAS ALAT Certification is preferred. Advancement to LAT or LATG certification is desirable. Work Environment: Position requires working closely with animals. Some noises may be associated with this position. Ability to lift 30 pounds required. The work environment characteristics described here are representative of those an employee encounters while performing the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions. Weekend and Holidays: This position is deemed essential personnel. Weekend and Holiday work is required. This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business. To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.

Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious diseases. Summary: Provides strategic, technical and operational Project Management leadership to Preclinical Development (PCD) and Drug Safety & Pharmacometrics (DSP), and at times to other departments within REGN. Influences project teams on operational and strategic areas of increasing complexity to ensure that programs are driven to completion. Leads cross-functional or cross-departmental process improvement initiatives of moderate to high complexity and of increasing strategic importance. Responsibilities: Provides strategic and operational Project Management leadership and support to cross-functional or cross-departmental teams for multiple programs or projects of moderate to high complexity. Influences program strategy, goals and plans. Leads PCD/DSP activities for multiple programs ensuring alignment of deliverables, plans, resources, timelines, budget re-forecast, risk/issue mitigation with those of overall project strategy and plan. Ensures effective communication to champion and convey project strategy, deliverables and plans across PCD, DSP, Project Teams and REGN. Independently assesses impact of individual programs on overall needs of the project, function and portfolio needs. Makes operational and strategic recommendations on areas of high complexity to project teams. Leads cross-functional or cross-departmental process improvement initiatives of moderate to high complexity Ensures effective relationships and collaborations with others in order to accomplish shared objectives. Influence and negotiates skillfully in difficult situations. Proactively identifies areas of increasing complexity (operational and/or strategic) and identifies innovative solutions and approaches for process improvement. Independently develops and gains alignment on solutions. Drives implementation of solutions of moderate to high complexity. At times, may provide operational and/or strategic Project Management support to specific selected initiatives within PCD and/or DSP May have supervisory responsibility with Managers and Associates reporting into role. Independently applies technical knowledge (scientific, drug development and/or project management) to drive development and implementation of new and unique concepts, techniques and standards. Partners with Team Leaders to identify and resolve any project, team and/or individual performance issues. Requirements: 12+ years of relevant project management experience High level of cross-functional technical knowledge and a proven track record in drug development - pharmaceutical/biotech industry. Working knowledge of project management techniques and concepts as they apply to the drug development / pharmaceutical industry. Proficient in relevant software: MS Project, Excel, PowerPoint, Word, etc. in addition to general knowledge of shared work environments. Experience with Qlikview a plus. This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business. To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.

Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious diseases. Summary: We are seeking a highly motivated and experienced research associate to join the Muscle and Metabolism Group to support our discovery and development efforts pertaining to liver-related metabolic diseases. The individual will be responsible for the execution of in vitro and in vivo biological experiments necessary to develop cell-based and animal models for testing of experimental therapeutics and for mechanistic biology studies. The ideal candidate will have in-depth in vitro or in vivo technical expertise, be hardworking, flexible, innovative and able to function effectively in a fast-paced environment. They will also have excellent communication skills and be able to work well in a team. Responsibilities: • Strong in vitro and in vivo technical expertise is required. The ideal candidate will have expertise spanning both in vitro and in vivo techniques. • In vitro technical expertise including, but not limited to: Tissue culture, transfection, FACS, and in vitro cell-based assay development Western blotting, chromatography, immunoprecipitation, and ELISA development • Molecular biology including molecular cloning, mutagenesis, DNA/RNA isolation, qRT-PCR, CRISPR immunohistochemistry, immunofluorescence staining and in situ hybridization bright-field, fluorescent, and confocal microscopy and respective image analyses In vivo technical expertise including, but not limited to: • Mouse handling, injections (IP, SC, IV), bleeds (tail vein, retro-orbital, submandibular) oral and IP tolerance tests (glucose, insulin, lipid) • minor survival surgeries (ie osmotic pump implantation) major survival surgery experience is an asset • The candidate will also perform relevant data analysis and interpretation, collate data for presentation or reporting, and present data at group meetings. • The candidate will be responsible for maintaining accurate and complete laboratory records. Requirements: • BS/MS + 2+ years' experience • Strong in vitro and in vivo technical expertise is required. The ideal candidate will have expertise spanning both in vitro and in vivo techniques. • Proficiency in software for data analysis (e.g., DNA sequence alignment, Excel, Prism, FlowJo) and data reporting/presentation (e.g., Word, PowerPoint). • Ability to multi-task and perform work with a high degree of attention to detail. • Ability to troubleshoot and intepretate data independently. • Excellent oral and written communication skills. • Ability to collaborate productively with different functional groups. • Strong organizational and timely record-keeping skills. This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business. To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.

Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious diseases. Summary: VelocImmune (VI) Next is a technology development group at Regeneron that invents state-of-the-art tools for biologic drug discovery. We are seeking a motivated, accomplished researcher to investigate and help develop new antibody and cell-based therapies. This is an opportunity for a candidate with strong molecular & immunology skills to join a team developing industry-leading technologies and medicines. Responsibilities: • Conduct experiments, independently and collaboratively, investigating new technologies in antibody and T cell therapeutics. • Develop methods to express and characterize candidate therapeutic molecules from the VelocImmune pipeline in primary cells and cell lines, using Crispr/Cas9, gene targeting, viral vectors, flow cytometry, and immunologic assays. • Develop and perform molecular, cell-based, and immunologic assays to screen and prioritize candidate molecules. Experience with high-throughput assays is a major plus. • In vivo testing of experimental antibody and cell therapies, using tumor models in mice. • Contribute to the design and analysis of mice with modified immune loci and targeted gene humanizations for novel therapeutics discovery. • Evaluate mouse and cell-based models with NGS (next generation sequencing) and immune repertoire analyses. Experience with NGS data analysis and/or coding skills, especially in immunogenomics, strongly preferred. • Careful, thorough record keeping, data summarization, and presentation of results in formal and informal meetings. Requirements: • Strong skills in molecular biology and cloning, including vector construction, PCR, and extraction/analysis of DNA, RNA, and proteins. • Knowledge and experience with NGS methods is strongly preferred, including proficiency in Python, R, or other coding language. • Strong skills and experience in mammalian cell culture and manipulation is required, including transfection, stable line development, and viral vectors. Growing and manipulating primary cells is a major plus. • An established background in immunology, especially T and B cell biology. • Experience with multi-parameter flow cytometry is required. Experience and knowledge of immuno-assays (ELISA, Elispot, MSD, cytotoxicity, proliferation, etc.) strongly preferred. • Experience handling and manipulating mice. Knowledge of tumor models is a major plus. • An ability and desire to design experiments, problem-solve, and troubleshoot independently. Ideas and independent thinking are strongly encouraged. • Strong organizational, time-management, and presentation skills. • Minimum of Bachelors Degree with 5+ Years experience or MS with 2+ years experience in Molecular Biology, Biochemstry, Immunology, or relevant field. This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business. To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.

Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious diseases. Summary: We are seeking a Ph.D. scientist with strong background in immunology to join the Bispecific Antibodies group. The position will support our ongoing efforts to design, produce and evaluate immunocytokines for immune-oncology indications. The successful candidate will work closely with a talented team of protein engineers and immunologists to characterize our novel therapeutics in preclinical in vitro/ex vivo experiments. Extensive knowledge and lab experience in multiparameter flow cytometry are required for this position. Additional expertise in molecular cloning or in vivo mouse tumor models is highly desirable. Responsibilities: • Independently design and execute complex multicolor flow cytometry (FACS) analysis on human and mouse immune cells, tumors, and cell lines. Conduct staining of both cell surface and intracellular antigens. Analyze data using FlowJo, Prism, Excel, etc. • Process tissue samples from mouse tumor studies (tumor, spleen, lymph node, blood, etc) for downstream FACS and ex vivo functional assays. • Perform in vitro/ex vivo functional assays (cell proliferation, cytotoxicity) and serum/supernatant analyte analysis (ELISA, MSD, CBA). • Independently conduct data analysis and troubleshooting. • Maintain complete, accurate, and timely record of experiments and data analysis. • Present data at group and inter-departmental meetings. • Collaborate within the Bispecific Antibodies group and with other functional groups at Regeneron. Requirements: • Ph.D. in Immunology, Oncology, Cell Biology or related fields. • Strong expertise in multi-color FACS analysis. • Experience in cell culture (primary cells and cell lines), tissue sample processing, and in vitro/ex vivo cell-based assays. • Experience in molecular cloning or mouse tumor models is highly desirable. • Excellent communication skills, ability to work productively in a fast-paced collaborative team environment. This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business. To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.

Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious diseases. Summary: We are seeking a biophysical chemist to provide analytical protein characterization through the use of cutting-edge biophysical technologies in the Protein Biochemistry group at Regeneron. The qualified candidate will be responsible for providing in-depth biophysical and biochemical characterization of therapeutic proteins to support mid-late stage development programs. The candidate is expected to take on a leading role in applying a diverse array of advanced biophysical techniques to deepen our knowledge of late stage biotherapeutic proteins and their inherent heterogeneity to support regulatory application for commercialization. Responsibilities: -Independently designs and conducts protein biophysical and biochemical experiments; analyzes data to elucidate quality attributes of therapeutic protein candidates and/or products. -Provides biophysical support for both upstream and downstream functional groups; helps solve development problems in real-time. -Takes a leading role in late stage development efforts to characterize size/charge variants, protein-ligand complexes, and high concentration protein solutions of therapeutic protein drug candidates. -Documents experiments, results and findings in laboratory notebook; presents work at group and department meetings; contributes to drafting of analytical characterization reports, regulatory submission sections, and peer-reviewed articles for publication. -May serve as a team representative in drug candidate-specific development team meetings, and share knowledge and expertise of biophysical chemistry at cross-function team meetings. -May provide some assistance to Research Associates conducting research and developmental work. -Participates in the general lab and instrument maintenance. Educational Requirements: -PhD in biophysical chemistry, molecular biophysics, or biochemistry with 0-3 years post-doctoral training in analytical protein characterization; experience in or collaboration with the biopharmaceutical industry an advantage. Experience: -Demonstrated ability to apply a variety of biophysical techniques to study one or more of the following: protein-ligand complex formation, protein aggregation pathways, and/or analytical characterization of viral vectors (or related gene therapy products). -Demonstrated expertise in light scattering (static and/or dynamic) and spectroscopic (e.g. CD, fluorescence, and/or Raman) principles and applications for analysis of proteins; working knowledge of SPR and mass spectrometry a plus. -Extensive hands-on experience in performing and trouble-shooting size-based (e.g. SEC, CE-SDS, and/or AUC) and charge-based (e.g. icIEF, IEX) separation techniques. -Experience with analytical ultracentrifugation (AUC) and/or field flow fractionation highly desired. -Strong command of general protein folding, structure, and thermodynamics. -High degree of proficiency in a variety of computer software for acquiring and analyzing light scattering, capillary electrophoresis, spectroscopic, and chromatographic data (e.g. ASTRA, 32 Karat, Empower). -Excellent oral and written communication skills are required. -A passion for science and innovation with a strong commitment to continual improvement and making significant contributions in a team environment. This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business. To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.

The Regeneron Genetics Center (RGC) is a wholly-owned subsidiary of the Company, whose goals are to apply large scale human genetics to identify new drug targets and to guide the development of therapeutics programs and precision medicine. Building upon Regeneron's strengths in mouse genetics and genetics-driven drug discovery and development, the RGC specializes in ultra-high-throughput exome sequencing, large scale informatics and data analysis encompassing genomics and electronic health records, and translating genetic discoveries into new biology and drug discovery opportunities. The RGC leverages multiple approaches including large population based studies, Mendelian genetics and family based studies, founder population genetics, and large-scale disease focused projects and has developed a network of over 50 collaborations with research organizations around the world. Including some of the largest sequencing studies in the world, such as the DiscovEHR study in collaboration with Geisinger Health System, and an initiative to sequence 500,000 participants with the UK Biobank, the RGC has built one of the largest human genetics databases, including sequence data from over several hundred thousand participants and rapidly growing. Our interests encompass a breadth of different areas across all therapeutic areas and the RGC is highly integrated into all facets of research and development at Regeneron. Program goals include target discovery, indication discovery, and patient-disease stratification. Objectives include advancing basic science around the world through public sharing of discoveries, providing clinically-valuable insights to physicians and providers of collaborating health-care systems, improving patient outcomes, and identifying novel targets for drug development. Summary: The RGC's Genome Informatics team leads the primary and secondary analysis of more than 500,000 samples a year, including production pipelines, cloud-compute infrastructure, and sequencing and variant quality control. Working closely with other RGC teams, our extensive genomics R&D portfolio supports multi-omics applications (RNA, long reads), unprecedented-scale variant calling, disease association studies, and loci-specific analyses that directly impact cutting-edge drug development. Under the direction of the QC lead, this entry-level role will support our efforts to develop, deploy and execute at-scale quality control protocols for both production and R&D experiments. Responsibilities: • Support all GI efforts to QC and analyze the world's largest genomic dataset • Preprare, validate and execute large-scale NGS analysis in cloud (AWS, GCP) and distributed compute infrastructure (SPARK) • Provide routine visualization of QC metrics, compute performance, and resource usage for RGC production • Support QC lead in validating production innovation • Create and develop in silico NGS standards and best practices • Work with GI leads to apply predictive models (e.g. machine learning) to QC metrics and analysis Requirements: • Bachelors in Computer Science or similar with minimum 1-3+ years relevant experience • Unix, Python • Visualization toolkit (R, Pandas) • Code repositories (GitHub, Sourceforge, Bitbucket) • Preferred: Standard bioinformatics tools (Samtools, BCFtools, VCFtools, BWA, GATK, Picard, BEDtools, PLINK) • Preferred: DNAnexus or other cloud experience This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business. To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.

The Regeneron Genetics Center (RGC) is a wholly-owned subsidiary of the Company, whose goals are to apply large scale human genetics to identify new drug targets and to guide the development of therapeutics programs and precision medicine. Building upon Regeneron's strengths in mouse genetics and genetics-driven drug discovery and development, the RGC specializes in ultra-high-throughput exome sequencing, large scale informatics and data analysis encompassing genomics and electronic health records, and translating genetic discoveries into new biology and drug discovery opportunities. The RGC leverages multiple approaches including large population based studies, Mendelian genetics and family based studies, founder population genetics, and large-scale disease focused projects and has developed a network of over 50 collaborations with research organizations around the world. Including some of the largest sequencing studies in the world, such as the DiscovEHR study in collaboration with Geisinger Health System, and an initiative to sequence 500,000 participants with the UK Biobank, the RGC has built one of the largest human genetics databases, including sequence data from over several hundred thousand participants and rapidly growing. Our interests encompass a breadth of different areas across all therapeutic areas and the RGC is highly integrated into all facets of research and development at Regeneron. Program goals include target discovery, indication discovery, and patient-disease stratification. Objectives include advancing basic science around the world through public sharing of discoveries, providing clinically-valuable insights to physicians and providers of collaborating health-care systems, improving patient outcomes, and identifying novel targets for drug development. Summary: The RGC's Genome Informatics team leads the primary and secondary analysis of more than 500,000 samples a year, including production pipelines, cloud-compute infrastructure, and sequencing and variant quality control. Working closely with other RGC teams, our extensive genomics R&D portfolio supports multi-omics applications (RNA, long reads), unprecedented-scale variant calling, disease association studies, and loci-specific analyses that directly impact cutting-edge drug development. The Senior Production Engineer will lead the innovation, design and development of the RGC's production genomics compute infrastructure. Under the direction of the GI-Prod Director, this role will apply the latest hardware, software and cloud technologies to innovative solutions in genomics data structuring, distributed compute workflows, and unprecedented scale data manipulation and mining. Responsibilities: • Optimize production workflows and architecture • Working with GI-Prod leads, innovate ultra-large scale variant freeze process (QC and joint-genotyping) • Work closely with RGC Data Engineering to integrate production with distributed compute environment • Develop tools for GI-Prod and RGC users to facilitate at-scale, at-speed genomics (e.g. QC, variant calling, multi-omics) • Lead GI-Prod software development best practices (version control, code repositories) • Extend R&D work of GI-Prod to scalable, distributable software (CNV detection, RNA-seq) #LI-GP1 Requirements: • Bachelors in Computer Science or similar & 5+ years • Unix, Python (or similar) • Code repositories (GitHub, Sourceforge, Bitbucket) • Cloud Platform (AWS, GCP) • Standard bioinformatics tools (Samtools, BCFtools, VCFtools, BWA, GATK, Picard, BEDtools, PLINK) • Genomics data formats and analysis • Distributed compute platforms This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business. To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.

Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious diseases. Summary: The Bioinformatics Data Engineer assists in the establishment, configuration, and maintenance of development environments running on the Amazon Web Services cloud and on-premise computing platforms. Furthermore, the candidate provides programming (specifically R & Python, but may include others) and infrastructural support for other bioinformatics developers across varied scientific disciplines. The position also oversees the onboarding of developers, communication of best practices and generation of usage reports. The post holder works closely with Research IT, IT-Cloud Services, scientists, and third parties to create compute environments and centralize research data repositories geared towards research activities. Responsibilities: • This role requires strong familiarity with the Linux environment, including extensive scripting (such as shell, R, Python) experience, configuring software, as well as supporting pipelines. • Provision and maintain data analytics platforms supporting our cutting-edge antibody discovery and production pipeline. • Provision and administer AWS resources (EC2, EBS, S3, RDS, etc). • Provide expertise in developing scientific applications and optimizing use of platform infrastructure Write software infrastructure to support pipelines and workflows. • Install, configure, maintain, and troubleshoot software applications. • Evaluate and implement new infrastructural paradigms (e.g. AWS Batch/Kubernetes). • Develop and maintain documentation and best practices for users of the scientific computing environment. • Assist in the preparation of reports and presentations. #LI-GP1 Requirements: • Strong background in R, Python, and shell scripting • Linux system administration • AWS cloud deployment experience • Familiarity with database management systems such as MySQL, MongoDB, Oracle, PostgreSQL • Experience with high performance and cloud based computing • Familiar with code version control systems such as git, subversion, CVS • Experience in scalable cloud-based platform architecture design • Code debugging, profiling and optimization techniques Preferred Skills: • Effective communication of complex concepts to collaborators with wide range of expertise. • Web server administration • Willingness to work in and adapt to a fast paced, changing environment Preferred Background: • Experience with molecular biology and genomics • MS in computer science, bioinformatics, computational biology, or related disciplines + 1 year experience • BS in computer science, bioinformatics, computational biology, or related disciplines + 3 years experience • 2+ years of AWS DevOps experience • AWS Associate certification • Previous experience in an industrial setting This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business. To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.

Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious diseases. Summary: Seeking a versatile computational scientist to support clinical and research programs.Taking a lead role in these studies, the successful candidate will communicate effectively with researchers and clinicians, and develop methods to interpret diverse data types. Responsibilities: • Collaborate with scientists, clinicians and external collaborators. • Analyze multiomic, clinical, and genetic data from patient cohorts. • Develop statistically robust tools for analyzing diverse data sets, from both established modalities and from novel technologies, e.g. spatial transcriptomics. • Provide scientific direction, technical expertise and coordinating activities with other groups at Regeneron. • Present results to colleagues, senior management and collaborators. • Disseminate results in peer-reviewed journals and conferences. • Introduce novel research questions to drive our research forward. #LI-GP1 #LI-GP1 Requirements: • PhD + 2 + Years' relevant experience • Demonstrated professional or academic achievement in computational biology. • Proficiency in programming languages such as R, python, bash. • Experience in analysis of bulk and single-cell RNA-seq, metabolomics, and proteomics data. • Knowledge of state-of-the art bioinformatics tools and approaches to support drug discovery programs. • Excellent communication skills. • Team orientation, creativity, and ability to juggle multiple projects. • Ability to work with a multi-disciplinary team encompassing both scientific and strategic perspectives. Preferred job requirements • Expertise in machine learning algorithms • Knowledge and experience in genetics and biostatistics This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business. To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.