Regeneron Pharmaceuticals, Inc.

Regeneron Pharmaceuticals, Inc. Rensselaer, NY 12144, USA
Jan 23, 2020
Full time
Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious diseases. *Level to be determined based on qualifications relevant to the role* Summary: Responsible for developing and managing processes within and outside of Combination Product Development to deliver first-rate products to patients living with serious disease; reports to Director, Combination Product Development. Essential Duties and Responsibilities include, but are not limited to, the following: • Liaises between Combination Product Development and Drug Product Internal and External Manufacturing, Quality Assurance, Quality Control, External Manufacturing, and other IOPS groups to ensure complete and continued integration of CPD requirements and processes throughout Regeneron • Identifies opportunities for streamlined activities and improved performance within the broader business; works with CMC PM and DP PM to realize such opportunities and make them intrinsic to non-IOPS and external business operations • Works with Combination Product Development functional managers to ensure strategic alignment of their activities with business priorities and goals • Assembles forecasts and justifications for headcount, capital, and other departmental needs. Links strategic objectives with department resources and resource requests • Works with other functions to identify and realize synergies between their systems and our requirements to assure efficient implementation (e.g., continued integration of device data into existing data management systems) • Manages complex information requests from the IOPS site as well requests by alliance partners and external parties, assuring that information is provided in an accurate, complete, and timely manner • Responsible for the timely resolution of issues with processes or relationships, and involves the correct subject matter experts (SMEs) in the resolution process • Anticipates problems across the department and acts to prevent or minimize their impact Knowledge, Skills & Abilities: • Ability to maintain integrity and honesty at all times • Ability to work independently or as part of a team • Ability to communicate with transparency • Continuously drive to improve processes for improved performance • Demonstrate respectful behavior at all times • Ability to lead and be accountable for team's performance and results • Manage internal and external relationships • Develop strategy and create metrics to measure effectiveness of strategy • Lead through ambiguity and translate into actionable steps • Provide leadership to direct and indirect reports • Coaching and conflict resolution • Handle issues appropriately and with a sense of urgency • Prioritize based on business needs • Identify and effectively communicate risks • Ability to problem solve and identify root cause • Ability to communicate at all levels and across various functions • Ability to build, lead, and motivate team Education and Experience: • BS/MS in relevant field and eight or more years of related experience required; equivalent combination of advanced education and experience may be considered. • Strong interpersonal and relationship management skills are required • Experience in the biopharmaceutical and/or medical device industry is strongly preferred • Experience in business development, management consulting, strategic consulting, or project management is preferred This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business. To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.
Regeneron Pharmaceuticals, Inc. Rensselaer, NY 12144, USA
Jan 23, 2020
Full time
Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious diseases. Summary: Provides expertise in the design, deployment, and maintenance of industrial computerized process control and process monitoring systems in a biopharmaceutical manufacturing cGMP environment for Regeneron's Industrial Operation and Product Supply organization. Level to be determined based on qualifications relevant to the role Essential Duties and Responsibilities include, but are not limited to the following: • Provide advanced level of technical automation support and troubleshooting to Manufacturing, Quality Control, and Facilities according to established SOPs and departmental practices • Lead and perform investigations relating to manufacturing deviations and anomalies associated with automation systems and control system software • Develop and edit engineering design documents, technical evaluations, and test plans for cGMP process equipment and follow GAMP 5 guidelines • Lead engineering and validation projects as well as provide support to manufacturing activities with process control and process monitoring equipment software design, commissioning, protocol review, and testing to meet end user requirements • Update or author system specifications, user requirements, functional requirements, and system design specifications • Generate and execute necessary testing and qualification protocols as related to the overall design and performance of automated process and monitoring equipment • Lead multiple small to medium sized manufacturing process control projects related to corrective action, equipment performance improvement, and new equipment • Design, develop, and implement software/hardware improvements to automated process control and process monitoring equipment according to change control procedures • Develop and execute test plans for software/hardware improvements to automated process control and process monitoring equipment according to change control procedures • Provide guidance to Automation Personnel according to established SOPs and departmental practices • May provide training or presentations on basic automation systems and tasks to department personnel • Follow standard operating procedures and automation engineering documents • Develop and draft standard operating procedures and automation engineering documents • Complete assigned work with some management or senior engineering staff oversight • Communicate effectively with engineering staff and cross functional departments • Complete all associated training and maintain required qualifications and/or certifications • May supervise a small group direct reports of junior engineers and/or contractors within department • Performs all job duties and responsibilities in a compliant and ethical manner and in accordance with all applicable healthcare laws, regulations and industry codes Knowledge and Skills: • Advanced skills with programming and troubleshooting PLCs, HMIs, and computerized system design, installation, and support in a cGMP industrial setting • Expert in PLC/HMI logic programming and troubleshooting Allen-Bradley and Siemens products which involve the use of batch programming (S-88), data acquisition, and PID control • Demonstrated knowledge of electrical systems, instrumentation and controls • Strong knowledge of process control and machine automation in biotech or pharmaceutical manufacturing facility • Expertise in developing and editing Software Lifecycle Documentation, engineering design documents, technical evaluations, and test plans for cGMP process equipment and follow GAMP 5 guidelines • Strong understanding of bioprocessing equipment design principles and sanitary equipment design requirements • Strong written and verbal communication skills with ability to delegate tasks • Proficiency with standard business software is required (Word, Excel, etc.) • Able to balance changing priorities with increasing workload by making timely decisions • Able to interact with employees at all levels and cross functionally across multiple departments • Ability to manage and develop direct reports through mentoring and leadership Education and Experience: • BS in Engineering or related field and 5 years of experience in the design and maintenance of process control systems and/or data acquisition systems • Equivalent relevant experience in the design and maintenance of process control systems and/or data acquisition systems may be considered in lieu of a degree • Specific knowledge of Allen-Bradley and Siemens control system products and video graphic chart recorders is required • Direct experience in a pharmaceutical or biopharmaceutical manufacturing facility is preferred This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business. To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law. #LI-DR1
Regeneron Pharmaceuticals, Inc. Tarrytown, NY, USA
Jan 23, 2020
Full time
Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious diseases. These positions are in Oncology & Angio within Therapeutic Focus Area located in Tarrytown, NY. There are 8 openings for Summer 2020. Each opening is described below: Position 1: This student will have the opportunity to work with our team to study the oncogenic activities of genetically altered receptor tyrosine kinases (RTKs) in relevant cancer models, evaluate their potential as molecular targets for cancer treatment, and develop targeted therapeutic reagents. Receptor tyrosine kinases (RTKs) are essential components of signal transduction pathways that play key roles in cellular processes such as proliferation, differentiation and survival, hence the activities of RTKs are tightly regulated in normal tissues. Mutations in RTKs that result in aberrant activation of their downstream signaling pathways have been causally linked to many diseases including cancer. Consequently, the abnormally activated RTKs have emerged as drug targets for treatment of certain types of cancer, and will be the focus of this summer internship. Position 2: Our group uses in vivo and in vitro assays to study the drivers of liver cancer. This student will have a project examining growth factors and growth factor receptors implicated in liver cancer to determine cell growth dependence on these pathways. This student will use a variety of techniques including growth assays, reporter assays, western blot, selective inhibitors, and potentially CRISPR/Cas9 modified cell lines to elucidate the growth factor/growth factor receptor pathways driving proliferation of human and mouse liver cell lines. Position 3: The main focus of our group is to monitor and evaluate the immune response of patients to cancer therapy over time. We have access to tumors and primary immune cell samples from patients enrolled in different clinical trials that we use to determine the patient's response to treatment and eventually define biomarkers of the disease. The student will have the opportunity to learn basic laboratory techniques such as primary human immune cell culture and antigen-specific cell stimulation and work with more advanced technologies such as flow cytometry and perform data analysis. Position 4: This student will be working in the Human Anti-Tumor Immune Cell (ANTIC) laboratory in summer of 2020. This student will learn the fundamentals of working in a primary cell culture laboratory setting. This student will assist in tumor immune profiling studies which involve: dissociation of fresh resected tumors and isolation/enrichment of immune cells for various downstream assays including single cell sequencing, flow cytometry, chip cytometry, and NanoString capture and analysis. This student will also learn and assist in cell culture and immune-cell based techniques and assays. Position 5: We are investigating the role of several signaling pathways in liver biology, regeneration and tumorigenesis. This project will involve studying the effect of activating or inhibiting these pathways in cell culture models, as well as testing and optimizing co-culture systems of different cell types (hepatocytes and endothelial cells, etc.). Our group has also developed an in vivo model of liver re-population, which can be used to study the role of signaling pathways in regeneration. This student will also be involved in analyzing samples from these in vivo studies, by running ELISAs, western blots, and analyzing immunohistochemistry (IHC) data. Position 6: This student will investigate the mechanisms by which RNA splicing is perturbed in tumor cells. Our group and others have observed aberrant patterns of tumor-specific RNA splicing across a number of different cancer types. However, it is not fully appreciated how splicing is perturbed these tumor cells or to what extent these mis-spliced transcripts contribute to oncogenesis. This student will address questions using a series of bioinformatics and molecular biology techniques. Position 7: This student will be responsible for characterization of syngeneic orthotropic bladder cancer cancer models which are based on organoid culture. Laboratory techniques necessary to achieve this goal are: IHC, IF, 3D organoid culture, H&E, molecular cloning, lentivirus production and ELISA. Last 3 will be acquired throughout this internship. Position 8: Our group uses human immune system reconstituted mouse model to study activation of immune cells upon treatment with our in-house immunomodulators. We are interested in observing how these immune cells response to treatment in the presence and absence of tumor and well as combination affects of multiple immunomodulators. This student will work on immune cells isolated from these mice to observe if the activation is to tumor associated antigens or self antigens. Start building your skills at Regeneron. Position 1 : • Must be pursuing a Bachelors or Masters Degree • Must be majoring in Biochemistry, Molecular Biology, Biological Engineering, Biology • Experience with Mammalian cell culture, and basic molecular biology techniques Position 2 : • Must be pursuing a Bachelors Degree • Must be pursuing a degree in Biology or Immunology • Must have lab work experience Position 3 : • Must be pursuing a Bachelors or Masters Degree • Must be pursuing a degree in Chemistry, Biochemistry, Biology, Biotechnology, Immunology or Microbiology • Must be familiar with aseptic techniques and basic immunological assays such as ELISAs and Flow Cytometry Position 4 : • Must be pursuing a Bachelors of Science • Must be pursuing a degree Biology and/or a related Life Sciences area • Cell culture/laboratory experience preferred but not required Position 5 : • Must be pursuing a Bachelors Degree • Must be pursuing a degree in Biology, Biochemistry, Biomedical Engineering • Cell culture experience preferred but not required Position 6 : • Must be pursuing a Bachelors Degree • Must be pursuing a degree in Biology • Excellent attention to detail Position 7 : • Must be pursuing a Bachelors Degree Position 8 : • Must be pursuing a Masters • Must be pursuing a degree in Cell and molecular biology, Immunology, Biomedical engineering. • Experience with Primary Cell culture, Mouse dissections, Ag-Stimulation, Flow cytometry General Intern Program Information: • Must be enrolled in, or accepted to, an academic program pursuing a Bachelor's, Master's, PhD or PharmD • Summer Program is full-time (~40 hrs/wk) for at least 10 weeks and is paid • Prefer demonstrated leadership in areas such as campus activities, clubs, sports or the community • Minimum GPA of 3.0 • You will work with a specific manager on a project(s) • Enjoy weekly 1 hour Intern Program events: learn about other areas of the company from VPs and other employees, soft skills workshops, networking, volunteering, and more! • Present to your team on your summer project Transportation and Housing: • Housing stipend available for those students who meet mileage requirements • A free shuttle is offered from the North White Plains or Tarrytown train stations to the Tarrytown, NY or Sleepy Hollow, NY campuses • Get to know other incoming Interns on our closed LinkedIn page when you accept an offer This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business. To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.
Regeneron Pharmaceuticals, Inc. Tarrytown, NY, USA
Jan 23, 2020
Full time
Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious diseases. These positions are in Molecular Profiling within Technology & Discovery Centers in Tarrytown, NY. There are 3 openings for Summer 2020. Each opening is described below. Position 1: This position is in our Molecular Profiling group in Tarrytown, NY. This student will be developing an artificial intelligence method, such as natural language processing, for the classification of public gene expression studies. In particular, this work focuses on the extraction of features like therapeutic focus area and sample class from broad data set summaries and metadata. Altogether these methods will allow us to curate a large database of public gene signatures that can be used to empower data sciences in genomic studies. Position 2: This student will mainly work on cell type classification problem and statistical comparison method for cell composition. Single cell clustering is an essential step in analyzing single cell data. Louvain clustering algorithm is mostly used, but we realize the algorithm has some limitations that need to be improved. This student will test other options and develop new methods to cluster single cells using scRNA-seq data. If the intern has more time, they will work on HLA typing project in collaboration with the RGC, or data integration method across different sequencing data type. Position 3: This position is in our Molecular Profiling group. This student will be directly involved in the effort to discover new vaccine and/or treatment targets in microbial pathogens, including viruses, bacteria and fungi. This student will use a novel computational approach which takes advantage of the thousands of genome sequences available in public databases. This student will survey and compare these genome sequences to select the top most conserved genes. These genes will then be curated and ranked according to finely-selected criteria pertinent to antigens. Overall, this project aligns with the Molecular Profiling mission to characterize new gene targets with great antigenic potential in order to control the spread of infectious diseases. Start building your skills at Regeneron. Position 1: • Must be pursuing a Master's or PhD • Must be pursuing a degree in Data Science, Computational Biology, Computer Science, or related discipline • Desired technical skills include, but are not limited to, AI, machine learning, and natural language processing Position 2: • Must be pursuing a Master's or PhD • Must be pursuing a degree in Bioinformatics, Computational Biology, Statistics, Biostatistics, Bioengineering, Computer Science, or related discipline • Desired technical skills include, but are not limited to, Genomics and large data set analysis. Position 3: • Must be pursuing a Master's or PhD • Must be pursuing a degree in Data Science, Computational Biology, Computer Science, Viral-bacteria Genome Analysis, or related discipline • Desired technical skills include, but are not limited to, one or more programming languages in: R, Python, Linux bash, Perl, C++; Basic knowledge of genomics data, statistical modeling theory, machine learning, Bayesian statistics, cluster computing. General Intern Program Information: • Must be enrolled in, or accepted to, an academic program pursuing a Bachelor's, Master's, PhD or PharmD • Summer Program is full-time (~40 hrs/wk) for at least 10 weeks and is paid • Prefer demonstrated leadership in areas such as campus activities, clubs, sports or the community • Minimum GPA of 3.0 • You will work with a specific manager on a project(s) • Enjoy weekly 1 hour Intern Program events: learn about other areas of the company from VPs and other employees, soft skills workshops, networking, volunteering, and more! • Present to your team on your summer project Transportation and Housing: • Housing stipend available for those students who meet mileage requirements • A free shuttle is offered from the North White Plains or Tarrytown train stations to the Tarrytown, NY or Sleepy Hollow, NY campuses • Get to know other incoming Interns on our closed LinkedIn page when you accept an offer This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business. To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.
Regeneron Pharmaceuticals, Inc. Tarrytown, NY, USA
Jan 23, 2020
Full time
Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious diseases. Summary: Automation Associate (AA) at this level executes experiments under limited supervision, following written or oral instructions. They have a mastery of general laboratory techniques (e.g. pipetting) and performing immunoassays. Experience with laboratory automation and programming are desired but not required. Job Duties: • Understand, execute and edit protocols on liquid hander and robotic scheduler in applications including ELISA and sample management in a regulated environment. • Perform ELISA assays manually for assay development, training and troubleshooting with limited supervision. Ability to follow SOP, interpret and present results in meetings. • Operate and perform maintenance on a range of laboratory instrumentation. Communicate effectively with supervisor and Automation Associates within the Automation group, other groups within the company and/or outside vendors for equipment related assistance. • May provide hands-on support to end users on the operation, troubleshooting and maintenance of automation system and its peripherals. • May participate in programming projects in support of automating data analysis. • Maintain GLP compliance for all laboratory work and documentation related to automated assay verifications in accordance with regulations and company SOPs. Assist in maintaining cleanliness, safety requirements and GLP compliance in the laboratory. • Self-starter, highly organized and problem solver with technical, detail-oriented mindset. Strong analytical and written/oral communication skills. Team-oriented and experienced in working in a diverse and multicultural environment. Requirements: Experience with general laboratory techniques and performing immunoassays Experience with operating/programming liquid handlers and schedulers (preferred) Experience with object-oriented programming, e.g. Visual Basic (preferred) This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business. To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.
Regeneron Pharmaceuticals, Inc. Tarrytown, NY, USA
Jan 23, 2020
Full time
Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious diseases. Summary: The Manager, Global Clinical Development will partner with the Director, Global Clinical Development to help identify, manage and drive advancing Global Clinical Development wide initiatives. This role will support the Director of Global Clinical Development's key objective of ensuring initiatives being led by, or impacting, Global Clinical Development are appropriately surfaced, prioritized, resourced, and executed. This role will also support increasing more alignment, awareness and understanding of GCD initiatives and priorities across the GCD organization to ensure that the Director, Global Clinical Development is focusing in on the most critical items to drive business success. This role will be responsible for representing the Director, Global Clinical Development (as needed) at key cross functional meetings. With the expanding depth and breadth of the Global Clinical Development organization, this newly created position will require strategic thinking around key operational issues, organizational processes and procedures, and communication; while enabling effective planning and execution. This role is both strategic and facilitative, requiring a nimble thinker with strong interpersonal skills, business acumen and the ability to shift between diverse priorities adeptly. Job Duties: • Support the Director, Global Clinical Development's goal of developing, formalizing and managing a new process for portfolio and program reporting. This important deliverable will require working seamlessly with multiple GCD functional areas, program teams and other key stakeholders to ensure information can be aggregated and visually presented for leadership on a regular cadence. • Support the identification and prioritization of Global Clinical Development initiatives; monitor progress and communicate updates to internal teams and external stakeholders as appropriate. • Support the management of bi-weekly Global Clinical Development leadership team meetings, manage meeting action items and follow. • Support and help coordinate the GCD communication strategy, plan and implementation. Includes preparation of all GCD wide communications that are not supported by Corporate Communications. • Is part of the monthly reviews of GCD workforce/headcount, space planning activities, and other finance related GCD wide processes to identify trends and actions from the data review and discussion. • Help to identify, manage and coordinate GCD cross functional business initiatives. • Support the Director, Global Clinical Development's objective of developing/maintaining Senior Management and Board of Directors meeting materials and messaging on behalf of the organization. • Work collaboratively with other departments throughout the company on behalf of Global Clinical Development in support of corporate goals and objectives, when appropriate support cross functional company-wide projects or initiatives. • Build a thorough understanding of all core business functions of the organization and apply that knowledge to effectively support strategic and tactical initiatives consistent with corporate and Global Clinical Development objectives. • Act as representative for the Director, Global Clinical Development in appropriate meetings to gather information, provide input and facilitate efficient decision making. • When appropriate, partner with internal and external stakeholders to proactively identify and work to resolve potential challenges. • Coordinate and optimize critical activities, quarterly/annual planning processes. • Partner with Human Resources to support talent development and departmental optimization by identifying opportunities for increased engagement and productivity. Requirements: Education: Bachelors degree required. Advanced degree: PhD/MBA or PhD preferred Experience: 5+ years • Strong initiative with the ability to manage projects of varying complexity and timelines simultaneously. • Effective leader with strong interpersonal skills including the ability to build trust, influence and relationships across a large and diverse organization. • Ability to handle confidential information with discretion. • Strong communications skills, including the ability to summarize complex issues concisely. • High standards of excellence and attention to detail. • Self-starter who identifies and helps solve problems and is comfortable with ambiguity. This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business. To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.
Regeneron Pharmaceuticals, Inc. Tarrytown, NY, USA
Jan 23, 2020
Full time
Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious diseases. Summary: Assay Development Scientists may supervise one or more Research Associates in the development and validation of immunoassays, showing strong decision-making abilities in their area of expertise. They create a development strategy for their own developmental projects as well as the projects assigned to their direct reports, designing experiments, troubleshooting problems, organizing and interpreting experimental results and performing follow-up experiments. Their in-depth understanding of the science and technology enables them to independently drive the development and validation of assays and guide the work of others. Their ability to perform sophisticated technical tasks allows them to pursue projects that incorporate a diverse set of skills and work on multiple projects/experiments simultaneously. They understand the project goals and their impact on corporate timelines. They independently seek out any available background information, through literature searches, external meetings and informal discussions. Responsibilities: • Designs and executes immunoassays (e.g., ELISA) independently, based on protocols provided by literature, seminars and other scientists. Troubleshoots assay-related problems with no guidance of his/her supervisor and performs follow-up experiments. Suggests modifications to protocols or alternative protocols. • May supervise one or more Associate level scientists in the development and validation of immunoassays to support new programs. • Routinely performs multiple assays within the same day and can work on multiple projects simultaneously. • Summarizes and presents results to supervisor in a logical manner, verbally and in written reports or presentations. May present data to senior management. • Independently develops immunoassay methods and writes assay validation protocols. • Expertly performs validation experiments, summarizes results in a tabular manner. Writes/reviews validation reports. • Reads and critically evaluates the literature in a specialized scientific field. • Trains other lab personnel on his/her area of technical expertise. Serves as a role model and mentor within the group. • Communicates effectively with supervisor and other members of the Assay Development Group. Communicates with other groups within the company and/or outside vendors to obtain assay-related reagents or discuss reagents needs. • May participate in multi­disciplinary meetings such as joint project teams as Assay Development representative to help direct drug development programs. May write bioanalytical assays sections for IND and BLA submissions. • May evaluate new technologies for the development of immunoassays using new formats or techniques. • Maintains GLP compliance for all laboratory work and documentation related to assay validations in accordance with FDA regulations and company SOPs. Assists in maintaining GLP compliance in the laboratory. Educational Requirements: • A PhD degree Experience • A minimum of 2 years of post-degree laboratory experience. • Experience in an industrial setting is desirable. • Experience developing and/or validating pharmacokinetics (PK), biomarkers and/or immunogenicity (ADAs and NAbs) assays is preferred. This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business. To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law. #LI-EH1
Regeneron Pharmaceuticals, Inc. Tarrytown, NY, USA
Jan 23, 2020
Full time
Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious diseases. Summary: We are looking for a highly motivated Ph.D. scientist to join the Therapeutic Antibody Luminex team. The successful candidate will directly contribute to the identification of potential therapeutic antibodies, bi-specific antibodies and other antibody modalities and selection process in early discovery stage. The scientist will design and develop protein multiplexing immunoassays using Luminex or other high through-put technologies; compile multifaceted screening data and report finding to a cross-functional team. The candidate should have a strong background in biological sciences preferable biochemistry or immunology with hands-on experience in immunoassay development. Excellent interpersonal and communication skills are required, as this candidate will be expected to work productively in a collaborative, cross-functional team environment. Critical thinking and ability to maintain a high level of productivity in a fast-pace, deadline driven project-oriented team environment is essential. Responsibilities: • Design and optimize high-throughput multiplexing immunoassay to asses antibody therapeutic binding properties. • Design and execute antibody binding characterization and profiling using Luminex technology or other immunoassay platforms. • Explore and provide information on new bead-based screening technologies and expand the scope of the existing technologies • Organize and carry out high through put screenings according to target-specific antibody screening plans. • Summarize experimental results and inform the project team timely and present the results in inter-department working meetings. • Work successfully in cross-functional teams either as team member or as independent contributor. • This Scientist position comes with the potential to manage Research Associates Requirements: • A PhD in a related field of study • A minimum of two years of post-graduate degree with extensive knowledge of immunology and hands-on bench research/development experience required. • Experience in in-vitro protein characterization, such as chemical and/or enzymatic protein modification and protein structure-function relationship in the field of biochemistry or immunology is required. • Experience with in multiplexing screening using Luminex or other technologies (label-free sensor technology) is highly desirable. • High throughput screening and familiarity with automated systems are beneficial. • Experience using word processing, spreadsheet and graphical analysis software required. • Must be able to multitask and perform rigorous data analysis under time pressure. • Ideal candidate should have experience working as independent researcher as well as collaborative team member and communicate effectively within large team. • Excellent adaptability and flexibility are essential. #I-EG2 #dice This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business. To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.
Regeneron Pharmaceuticals, Inc. Tarrytown, NY, USA
Jan 23, 2020
Full time
The Regeneron Genetics Center (RGC) is a wholly-owned subsidiary of the Company, whose goals are to apply large scale human genetics to identify new drug targets and to guide the development of therapeutics programs and precision medicine. Building upon Regeneron's strengths in mouse genetics and genetics-driven drug discovery and development, the RGC specializes in ultra-high-throughput exome sequencing, large scale informatics and data analysis encompassing genomics and electronic health records, and translating genetic discoveries into new biology and drug discovery opportunities. The RGC leverages multiple approaches including large population based studies, Mendelian genetics and family based studies, founder population genetics, and large-scale disease focused projects and has developed a network of over 50 collaborations with research organizations around the world. Including some of the largest sequencing studies in the world, such as the DiscovEHR study in collaboration with Geisinger Health System, and an initiative to sequence 500,000 participants with the UK Biobank, the RGC has built one of the largest human genetics databases, including sequence data from over several hundred thousand participants and rapidly growing. Our interests encompass a breadth of different areas across all therapeutic areas and the RGC is highly integrated into all facets of research and development at Regeneron. Program goals include target discovery, indication discovery, and patient-disease stratification. Objectives include advancing basic science around the world through public sharing of discoveries, providing clinically-valuable insights to physicians and providers of collaborating health-care systems, improving patient outcomes, and identifying novel targets for drug development. Summary: We are looking for a talented Genetic Epidemiologist with strong quantitative skills to join our Cardiovascular, Metabolic and Musculoskeletal Therapeutic Area Genetics team. The post holder will have key responsibilities in mining large human genetics datasets including 100,000s of genotyped and sequenced participants, in partnership with other RGC teams, to translate genetic findings into new therapeutic insights. The key goals of the post will be (a) to empower the translation of genetic association findings into new therapeutic targets, indications and precision medicine approaches that will enable Regeneron to deliver better medicines to the patients who need them in the fields of Cardiovascular, Metabolic and Musculoskeletal Medicine; (b) to support existing pre-clinical and clinical development programs within Regeneron in these Therapeutic Areas using human genetics approaches; (c) to form strong partnerships with the Analytical Genomics, Clinical Informatics, other RGC's teams to accomplish the goals of the Therapeutic Area Genetics team, RGC and Regeneron at large. Responsibilities: • Design and execute complex analyses across datasets to accomplish the translational goals of the Therapeutic Area Genetics team. • Work in close collaboration with other Therapeutic Area Genetics team members and form a strong partnership with Analytical Genomics, Clinical Informatics and other RGC teams to deliver on complex, top-quality scientific endeavours in these Therapeutic Areas. • Generate, summarise, and present results in internal and external meetings to a variety of audiences. Lead or contribute to the writing of scientific reports and publications. • Represent the Therapeutic Area Genetics team in cross-functional initiatives within RGC and Regeneron. • Collaborate with external industry and academic partners in scientific consortia. Requirements: • PhD in Genetic Epidemiology, Statistical Genetics (with an applied focus), Human Genetics or similar and strong quantitative and analytical skills. • 5+ years of experience and/or an outstanding level of achievement in the field of large-scale human genetics post PhD. • Expertise in the genome-wide and gene-centric analysis of large human genetics datasets for translational insights. The successful candidate will use (a) Mendelian randomization to elucidate causal mechanisms and evaluate whether pharmacological treatment of a target is likely to be effective and safe; (b) polygenic risk scores to enhance etiologic understanding and genetic prediction, (c) fine-mapping and other prioritization approaches to identify causal variants and genes underlying genetic association signals and (d) will routinely combine information across multiple traits, variants and data sources to generate new insights. An outstanding candidate will have contributed to the application of these methods to important biological problems in the field of Cardiovascular, Metabolic and Musculoskeletal Medicine. • Expertise with modern cluster and cloud computing environments and with statistical analysis software (R environment for statistical computing, STATA) and human genetics analysis tools (METAL, GCTA, PLINK or similar). • Interest in understanding the genetic basis of Cardiovascular, Metabolic and Musculoskeletal diseases and translating this knowledge into therapeutic insights. An outstanding candidate will have previously worked on cardiovascular, metabolic or musculoskeletal phenotypes. • Ability to work in a highly interactive environment with a diverse team of colleagues. Ability to provide mentorship and guidance to more junior colleagues to help them develop their full potential and build new skills and abilities. • Outstanding communication skills and an ability to summarize and present the results of human genetic studies to a variety of technical audiences, ranging from experts in statistical genetics, human genetics, biology, drug design and medicine. • A commitment to high-quality science and to the highest standards of research and work ethics and integrity. This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business. To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.
Regeneron Pharmaceuticals, Inc. Tarrytown, NY, USA
Jan 22, 2020
Full time
Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious diseases. Summary: The Biostatistics and Data Management group is looking for a Biostatistician to support Early Clinical Development and Exploratory Sciences. This position is for a qualified statistician with experience in the pharmaceutical/biotechnology sector, to collaborate in cross-functional drug development teams to execute innovative development strategies for compounds entering early clinical development. Job Duties: The incumbent will work under the direct supervision of permanent statisticians, to work with cross-functional teams to articulate drug development questions, assess the feasibility of endpoints and frame statistical approaches to address those questions, design clinical experiments and interventional studies to generate the requisite data and analyze the resulting data, and work with teams to appropriately interpret the results and make decisions. The incumbent will work with more experienced project statisticians to co-author clinical study protocols, co-author statistical analysis plans, and perform statistical analyses for interim and final reports. Responsibilities • Under direct supervision and guidance of senior departmental staff, provide support to a clinical study team on all relevant statistical matters. As member of study team, ensure the clinical study is conducted in a manner that supports planned statistical analysis. • Under supervision and guidance of senior departmental staff, participate in preparation of study protocol and amendments. Perform relevant sample size calculations and write statistical methodology section of the protocol. • Review case report form (CRF) and provide comments and feedback. • Develop statistical analysis plan (SAP). • Provide programming team with definitions and documentation for derived variables needed to produce planned Tables, Figures and Listings (TFLs). Develop data and programming specifications jointly with programmers. • Perform statistical analysis according to the SAP, validate analysis programs, review TFLs, prepare statistical methods and results sections for the clinical study report (CSR), provide statistical insight into interpretation and discussion of study results, and work with the study team to move the CSR through review /approval process. Requirements: PhD or equivalent degree in statistics/biostatistics or related disciplines OR MS with >3 years relevant work experience. • Knowledge of drug discovery and development and ability to integrate statistical concepts into drug discovery and development strategies. • Strong influence and leadership skills, with a track record of collaboration with scientists and researchers at Biostatistician level. • Solid knowledge of statistical analysis methodologies, experimental and clinical trial design • Must be able to work productively in a fast-paced collaborative environment, with demonstrated critical thinking skills, and effective communication and presentation skills. • Expertise in statistical software, such as R, SAS, WinBUGS, STAN, and/or Matlab is required Preferred: • Experience with linear and nonlinear models, Bayesian methodology, statistical decision theory, modeling and simulation, and model-informed drug development • Experience in clinical pharmacology studies, pharmacokinetics (PK), and PK/PD modeling This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business. To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law. #LI-LR1, LMR
Regeneron Pharmaceuticals, Inc. Tarrytown, NY, USA
Jan 22, 2020
Full time
Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious diseases. This position is in Cell Culture Development within Preclinical Manufacturing & Process Development in Tarrytown, NY. There is 1 position for Spring AND Summer (full time, about 7 months from January to August 2020). This student will be exposed to real-world responsibilities, comprehensive basic training and guidance to participate in the development of new media and feed formulations to improve the production of biotherapeutics. The student will support cell culture experiments in shake flasks, ambr and bench scale bioreactors. He/she will assist with Metabolic Flux Analysis (MFA), predictive modeling, statistical data analysis, among other techniques to increase our understanding and improve cell culture process efficiency based on evaluation of historical and real time process and cell metabolism data. Familiarity with data analysis techniques and modeling is highly desirable. Concepts from coursework in metabolism, mass transfer, programing, kinetics and biotechnology will be applied to experimental and data analysis activities. The ability to design experiments, interpret results, and communicate findings will be developed as part of the cooperative education experience. Start building your skills at Regeneron. • Must be a rising 4th year or above • Must be pursuing a degree Chemical, Biochemical or biomedical Engineering and Computer Science • Must have laboratory and programming experience- Cell culture, Programming (Linux, R, Python) preferred • Preferred previous experience in biotechnology in particular cell culture and data analysis General Co-op Program Information: • Must be enrolled in, or accepted to, an academic program pursuing a Bachelor's, Master's, PhD or PharmD • Program is full-time (~40 hrs/wk) and is paid • Prefer demonstrated leadership in areas such as campus activities, clubs, sports or the community • Minimum GPA of 3.0 • You will work with a specific manager on a project(s) • Enjoy regular 1 hour Co-op Program events: learn about other areas of the company from employees, soft skills workshops, networking, volunteering, and more! • Present to your team on your project(s) Transportation and Housing: • A free shuttle is offered from the North White Plains or Tarrytown train stations to the Tarrytown campus • Get to know other incoming Interns on our closed LinkedIn page when you accept an offer This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business. To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.
Regeneron Pharmaceuticals, Inc. Rensselaer, NY 12144, USA
Jan 22, 2020
Full time
Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious diseases. Summary: Designs, specifies and commissions new and renovated biopharmaceutical process and clean utility equipment; provides engineering support and leads deviation investigations for existing equipment and manufacturing processes. Essential Duties and Responsibilities include, but are not limited to, the following: • Designs and specifies cGMP process equipment, piping, and/or controls including development and review of engineering documentation. • Manages small-to-mid sized projects related to process equipment and clean utilities including start-up and commissioning. • Assists/leads in the design review, site acceptance and installation of equipment. • Prepares piping and instrumentation diagrams and other related drawings. • Develops Process Flow Diagrams for manufacturing processes. • Supports QA/Validation department by preparation of design documents and assists in protocol execution. • Assists in investigations of process equipment, utility systems, and control system anomalies, as well as safety incidents. • Implements corrective/preventative actions for existing equipment and manufacturing processes. • Prepares engineering evaluations and test plans for and executes modification change control documentation. • Supervises mechanical, electrical, and automation contractors. • Maintains a clean and safe working environment by enforcing procedures, policies, and regulations. • Maintains company reputation by enforcing compliance with local, state, and federal regulations Education and experience: • Requires BS/BA or higher in chemical or biochemical engineering and 2 years of experience in project/process engineering or equivalent combination of education and experience. • Direct experience with biopharmaceutical process equipment is preferred. Knowledge, Skills, and Abilities: • Thorough knowledge of cGMPs and sanitary equipment design requirements. • Working knowledge of process control systems and automation. • Thorough knowledge of engineering documentation required for cGMP process equipment. • Working knowledge of biopharmaceutical equipment. • Strong written and oral communication skills. • Ability to understand project plans and schedules. • Working knowledge of word processing, spreadsheets, database management software, CAD software, and PCs. This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business. To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.
Regeneron Pharmaceuticals, Inc. Tarrytown, NY, USA
Jan 22, 2020
Full time
Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious diseases. Summary: We are seeking a self-motivated and ambitious individual to join the human anti-tumor T cell biology team in Oncology Research at Regeneron in Tarrytown, NY. The successful candidate will have a Masters degree in immunology or a related field as well as 3+ years of hands-on experience, and will work on a team that performs functional T cell assays on primary human blood and tumor immune cells. The work will mainly support clinical immune monitoring of samples from patients who are receiving immune modulating cancer therapies. Key experimental approaches include both direct ex vivo analysis as well as in vitro immune cell culture. The candidate will be responsible for developing and executing functional assays on clinical materials using high-parameter flow cytometry and single cell sequencing. Previous hands-on experience with functional T cell assays and read-outs (antigen re-exposure assays, ELISPOT, multimer staining, functional flow cytometry) is desired. The position also involves multi-color flow cytometry and cell sorting for downstream analysis. Preference will be given to candidates with bioinformatic data analysis expertise. Responsibilities: Expertly perform primary human immune cell co-cultures Perform antibody and multimer staining for multiparameter flow cytometry Independently operate high-parameter flow cytometers and cell sorters Perform high-throughput T cell screening to determine antigen-TCR pairing Collaborate with other internal research and clinical teams to jointly develop and advance technology-forward methods to evaluate human anti-tumor T cell function. Independently develop and execute primary human immune cell functional assays. Independently design multicolor flow cytometry panels and perform analysis. Independently perform primary cell sorting. Requirements: Minimum of 3 years of experience in T cell biology MS or BSc in immunology or related discipline preferred Minimum of 3 years of hands-on technical experience in tissue culture, with preference for primary cell culture experience Strong written and oral communication skills Experience working in cross-functional teams Prior experience with cell sorting preferred. Prior experience with high-throughput immunological screening and single cell sequencing including TCR sequencing is preferred. This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business. To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.
Regeneron Pharmaceuticals, Inc. Tarrytown, NY, USA
Jan 22, 2020
Full time
Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious diseases. Summary: We are seeking a highly creative and motivated scientist to develop and integrate new technologies and innovative mouse genetic disease models as part of our in-house mouse phenotyping screen, which uses genetically modified mice to identify and evaluate targets of therapeutic potential. This individual will be responsible for developing and implementing technologies to aid the discovery of novel targets for a variety of therapeutic areas. Expert scientific knowledge of one or more organ system and/or area of disease biology as well as a background in working with genetically modified mouse models is desireable. This individual will have demonstrated abilities in the development of new methods or technologies to advance the understanding of biology. Responsibilities: Development of technology and disease models in order discover therapeutic targets in diverse disease focuses. Processes should include testing and use of the most current technologies, streamlined database integration and robotic automation. Assays to be developed may include: • Models of immune challenge, such as inflammation and autoimmune responses. • Behavioral assays • Tumor models for oncology • Measurements and challenges of general metabolism Technologies may include: • Novel multiplexed high resolution methods for RNA in situ and immunohistochemistry, proximity detection and colocalization. • Testing, optimize and implementation of genetic reporter systems for evaluating gene expression The individual will have the opportunity to pursue interesting leads identified by the screen and these new methods for futher clinical development and/or publication. Requirements: A minimum of a PhD or MD with 0-6 years relevant postdoctoral experience. Ability to organize and present data to all levels Expertise in molecular and cell biology, genetically modified mice and disease modeling. Expertise in assay development, particularly in the fields of oncology, immune challenge models or behavior. Preferred skills: Familiarity with current statistical programs This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business. To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.
Regeneron Pharmaceuticals, Inc. Tarrytown, NY, USA
Jan 22, 2020
Full time
Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious diseases. Summary: We are seeking a research associate to work in our Protein Development group. This position will be focused on preparation of proteins to support the efforts of Regeneron's structural biology group in X-ray crystallography and cryo-electron microscopy (cryoEM). The successful candidate will work closely with scientists in the structural biology group to develop purification procedures to deliver highly pure and homogeneous protein samples. Responsibilities: This work will be directed toward supplying the structural biology group with proteins or protein complexes for their research. In some cases, the purification procedure will be straightforward, previously tested in house or in the scientific literature, in which case the priority will be to execute the procedure as cleanly and carefully as possible, so that the resulting sample will be pure and homogeneous, raising the odds of a successful structure determination. However, in many cases, there will be no clear path to follow. In these cases, the individual in this position will need to collaborate with the structural biology scientists to develop a new purification procedure, drawing on available literature and previous experience, but then breaking new ground and using results from first attempts to refine the procedures for the next attempts. In the most challenging cases, we will be attempting things that may have never been done before. The proteins to be purified will be very diverse, giving the position holder a chance to learn and experiment with a wide variety of cutting-edge purification techniques, including automated purification method development, high-throughput capillary electrophoresis, and SEC-MALS. Although mammalian and insect cell protein expression will be performed by other groups, this position offers the opportunity to carry out some bacterial protein expression as well, in collaboration with Protein Development scientists. Requirements: Candidates should have a minimum of a bachelor's degree with 2-3 years of directly relevant protein purification experience. Prior experience in protein crystallization or cryoEM sample preparation is not required, but would be helpful. The successful candidate should have a track record of protein purification in a variety of projects. The structural biology samples to be worked on in this position will come from different expression systems, including bacteria, insect cells, and mammalian cells, and will include both soluble and membrane proteins. A candidate with experience across this spectrum will be preferred, although we do not expect any one person to have done all of this. The candidate should have experience with most standard protein purification techniques, including size-exclusion, ion exchange, and affinity chromatography, and protein characterization by SDS-PAGE and Western blotting. This position will involve work on multiple projects simultaneously, so excellent record-keeping and time management skills are very important, as well as the ability to absorb new information rapidly. The candidate should be highly self-motivated and capable of working independently with suitable guidance. Familiarity with lab database and LIMS systems will be an advantage. #I-EG2 #dice This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business. To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.
Regeneron Pharmaceuticals, Inc. Tarrytown, NY, USA
Jan 22, 2020
Full time
Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious diseases. Summary: Purification and biochemical characterization of protein reagents and antibodies in support of the company's VelocImmune fully human antibody pipeline and Immune Oncology programs. Experience protein purification is required. This position will be primarily focused on purification of therapeutic reagents and antibodies for ongoing therapeutic programs using standard purification systems and some automated equipment. Database entry and documentation of purified characterized reagents in LIMS and power point reports is critical. Must be able to work productively in a fast-paced collaborative team environment. Excellent communication skills are essential. Responsibilities: Protein purification and characterization using liquid chromatography such as affinity, IEX, HIC, and SEC. Characterization of reagents by Western blotting, SDS PAGE electrophoresis, SEC chromatography, LAL, and concentration by UV. Protein conjugation of reagents with biotin, Alexa488, and PE, and other tags. Interpretation of results, documentation by ELN, and power point presentation slides for characterization and documentation of reagents and antibodies purified. Must be able to work productively in a fast-paced collaborative team environment. Excellent communication skills are essential. Requirements: Protein Purification by affinity, Ion exchange, and SEC chromatography Experience running the AKTA Explorer SDS Page Electrophoresis Western Blotting Sterile techniques Good Lab practices Spectrophotometry Data entry and notebook keeping using ELN #I-EG2 #dice This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business. To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.
Regeneron Pharmaceuticals, Inc. Basking Ridge, Bernards, NJ 07920, USA
Jan 22, 2020
Full time
Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious diseases. Summary: A statistical programmer consultant provides timely support to the study team on all programming matters according to the project strategies. Requirements will be identified according to a Statistical Analysis Plan and programming specifications using internal standards and guidelines. The incumbent implements and executes the programming and project standards. Works independently in the design and testing of program logic, coding programs, program documentation and preparation of programs. Supports ongoing clinical studies requests for statistical and non-statistical analyses. Meets statistical ad hoc requests of senior management. Provides documentation and consistent maintenance of code, logs, and output in a regulated environment. Responsibilities: • Support programmer within a study team involved in the creation and QC of analysis datasets TFL's or standard tools following Regeneron standard data models or user requirements. • Apply standard tools developed for the study or project. Participate in development of new standards and tools. • Follow all company SOP and guidelines in the creation of the programming deliverables. • Adheres to procedures surrounding retention of data, records, and information for clinical studies. Requirements: Statistical Programmer Consultant: SAS, (Base, Stat, Macro, graph). MS. (BS) in Statistics, Computer Science, Mathematics, Engineering, Life Science or related discipline with 5 -7 years of programming experience preferably in processing clinical trial data in the biotechnology, pharmaceutical or health related industry. SAS Certification a plus. • Experience in SAS programming, preferably in a clinical data environment. • Exposure of relational database structure • Understanding of reporting systems. • Experience with implementing standardization methodology. • Demonstrated teamwork and interpersonal skills, strong verbal and written communication skills in a global environment. • Ability to support study requirements with challenging timelines under direct supervision by the programming lead This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business. To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.
Regeneron Pharmaceuticals, Inc. Rensselaer, NY 12144, USA
Jan 22, 2020
Full time
Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious diseases. Summary: Responsible for designing, developing, implementing, and maintenance of industrial computerized process control and process monitoring systems (PLC's and HMI's) in a biopharmaceutical manufacturing cGMP environment for Regeneron's Industrial Operation and Product Supply organization. "Level to be determined based on qualifications relevant to the role" Essential Duties and Responsibilities include, but are not limited to the following: • Provide technical automation support and troubleshooting to Manufacturing, Quality Control, and Facilities according to established SOPs and departmental practices • Perform investigations relating to manufacturing deviations and anomalies associated with automation systems and control system software • Develop and edit engineering design documents, technical evaluations, and test plans for cGMP process equipment and follow GAMP 5 guidelines as they relate to assigned projects • Support engineering and validation projects as well as provide support to manufacturing activities with process control and process monitoring equipment software design, commissioning, and testing to meet end user requirements • Support automation activities by updating or authoring system specifications, user and functional requirements specifications, generating and executing necessary FAT and SAT protocols • Support small manufacturing process control projects related to corrective action, equipment performance improvement, and new equipment • Design, develop, and implement software/hardware improvements to automated process control and process monitoring equipment according to change control procedures (PLC's and HMI's) • Develop and execute test plans for software/hardware improvements to automated process control and process monitoring equipment according to change control procedures • Complete assigned work with some management or senior engineering staff oversight • Communicate effectively with engineering staff and cross functional departments • Complete all associated training and maintain required qualifications and/or certifications • May provide training or presentations on basic automation systems and tasks to department personnel • Follow standard operating procedures and automation engineering documents • Update existing standard operating procedures and automation engineering documents • Performs all job duties and responsibilities in a compliant and ethical manner and in accordance with all applicable healthcare laws, regulations and industry codes Knowledge and Skills: • Experience programming and troubleshooting PLC's, HMI's and computerized system design, installation and support in a cGMP industrial setting preferred • Skilled at troubleshooting PLC's and HMI's and systems in a pharmaceutical or biopharmaceutical manufacturing facility. Specific knowledge of Allen-Bradley and Siemens control system products and video graphic chart recorders is required • Basic knowledge of ladder logic, electrical systems, instrumentation, and controls • Demonstrated knowledge of process control and machine automation in biotech or pharmaceutical manufacturing facility • Ability to develop and edit Software Lifecycle Documentation, engineering design documents, technical evaluations, and test plans for cGMP process equipment and follow GAMP 5 guidelines • Basic understanding of bioprocessing equipment design principles, sanitary equipment design requirements, and data integrity regulations • Strong written and verbal communication skills • Proficiency with standard business software is required (Word, Excel, etc.) • Able to balance changing priorities with increasing workload by making timely decisions • Able to interact with employees at all levels and cross functionally across multiple departments Education and Experience: • Associate Level - BS in Engineering or related field • Mid Level - BS in Engineering or related field and two years of experience in the design and maintenance of process control systems and/or data acquisition systems • Equivalent relevant experience in the design and maintenance of process control systems and/or data acquisition systems may be considered in lieu of a degree • Experience programming and troubleshooting PLC's, HMI's and computerized system design, installation and support • Experience in a pharmaceutical or biopharmaceutical manufacturing facility is preferred This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business. To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.
Regeneron Pharmaceuticals, Inc. Tarrytown, NY, USA
Jan 22, 2020
Full time
The Regeneron Genetics Center (RGC) is a wholly-owned subsidiary of the Company, whose goals are to apply large scale human genetics to identify new drug targets and to guide the development of therapeutics programs and precision medicine. Building upon Regeneron's strengths in mouse genetics and genetics-driven drug discovery and development, the RGC specializes in ultra-high-throughput exome sequencing, large scale informatics and data analysis encompassing genomics and electronic health records, and translating genetic discoveries into new biology and drug discovery opportunities. The RGC leverages multiple approaches including large population based studies, Mendelian genetics and family based studies, founder population genetics, and large-scale disease focused projects and has developed a network of over 50 collaborations with research organizations around the world. Including some of the largest sequencing studies in the world, such as the DiscovEHR study in collaboration with Geisinger Health System, and an initiative to sequence 500,000 participants with the UK Biobank, the RGC has built one of the largest human genetics databases, including sequence data from over several hundred thousand participants and rapidly growing. Our interests encompass a breadth of different areas across all therapeutic areas and the RGC is highly integrated into all facets of research and development at Regeneron. Program goals include target discovery, indication discovery, and patient-disease stratification. Objectives include advancing basic science around the world through public sharing of discoveries, providing clinically-valuable insights to physicians and providers of collaborating health-care systems, improving patient outcomes, and identifying novel targets for drug development. Summary: Contribute to the analysis and interpretation of 100,000s of genotyped and sequenced humans, with the goal of generating the knowledge that will enable Regeneron to deliver better medicines to the patients who need them. Work collaboratively with other experts in genomic data analysis, biology, computation and medicine to design, execute and refine analyses that connect genetic variation to human diseases and health and to develop the methods and tools that will enable these analyses to be executed and interpreted at scale. Continually learn and acquire skills that are essential for a productive career at the intersection of human genetics, biology, health and drug development. Responsibilities: Run quality control and filters on new large-scale genetic and phenotypic datasets, and provide summaries and visualizations of these steps Generate optimized workflows for executing genome-wide association testing using a cloud-based (AWS) pipeline Support the development and deployment of cloud-based pipelines and applications by writing and testing new features that enable automation of genomic data analysis Implement scalable, portable, and unit testable code, and be able to review code for efficiency and correctness Design and develop new pipeline and application features based on user feedback Create and test new standards, methods, and best practices in the fields of statistical genetics and computer science Effectively communicate methods and present code to a variety of technical audiences Work in a highly interactive environment with a diverse team of colleagues Requirements: Bachelors degree in Computer Science, Biomedical Engineering, or related field with minimum 2-3 years relevant experience in Biotechnology or Genetics Knowledge of many standard bioinformatics tools (PLINK, HTSlib, tabix, VCFtools, Picard) and data formats (e.g. VCF, BED, BGEN) Skilled at working on a linux/unix command line and able to develop code in a high-level programming language (preferably Python) Ability to generate visualizations of datasets using (for example) R/ggplot2 or Pandas/matplotlib Familiarity with standards in version control and code repositories (GitHub, Sourceforge, Bitbucket) Experience in cloud computing environments (AWS, GCP) Familiarity with common strategies and visualizations in genetics and association testing (PCA, Manhattan/QQ plots, LambdaGC) Preferred: Masters degree in Bioinformatics, Computational Biology, Biostatistics or similar field Experience designing and developing web applications (HTML5, Javascript, D3, Flask) Knowledge of some current state of the art tools for association testing (BOLT, SAIGE, GCTA, EPACTS) Experience using a workflow language (CWL, WDL) and containerization (Docker) This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business. To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law
Regeneron Pharmaceuticals, Inc. Tarrytown, NY, USA
Jan 22, 2020
Full time
Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious diseases. Summary: The Associate Director/Director, Strategic Internal Communications, will be responsible for developing, planning and executing Regeneron's internal communications programs that engage Regeneron's 8,000+ employees globally. This includes leading our editorial strategy for our popular company intranet (and mobile app) and advancing other engagement initiatives and activities, including leader/manager communications, change communications, forums and town halls, culture communications programming, and more. The successful candidate will be a part of a global Internal Communications team that thinks strategically and executes at a high level to support our fast-growing company and our unique culture -- where colleagues are passionate about their work and our mission to bring important new medicines to patients in need. The Internal Communications team is part of the Corporate Communications & Citizenship department focused on developing strategies and programs in four key areas: building a strong corporate reputation for Regeneron, sustaining culture and driving engagement through employee communications, and entrenching corporate citizenship as core to Regeneron's identity - all while building understanding and support for our company, pipeline and science. Requirements: Responsibilities: • Develop and manage the editorial strategy and plan for RON, our popular company intranet, and RONda, our soon-to-launch employee mobile app -- two channels that help employees understand our science-based culture and how their work contributes to our mission and goals. • Oversee the team of individuals responsible for executing on our plan: direct report, IC team colleagues, agency partners, freelance writers, videographers, designers, etc., who contribute to our compelling content to tell the REGN story to our employees, our most important audience. • Lead our Science Made For initiative, which aims to bring patients and their stories to all REGN colleagues through a variety of channels and events. • Help in planning for our quarterly global townhall-style meeting, Regeneron Forum, an open Q&A format with all of our colleagues, and our annual all-company patient event. • Manage our Colleague Ambassador Network, a group of ~50 employees who provide input and feedback on our communications and engagement programs, and help to mobilize our work across the company. • Support communications efforts to sustain our culture and the continued rollout of the Regeneron Way, our values and behaviors. • Partner with various leaders and teams across the company to support strategic communications efforts. • Manage and/or influence internal and external resources (team members, freelancers, agencies) to support and execute on our employee communications priorities. • Stay on top of industry trends in employee communications and engagement to help educate our team and advance our work. • Develop and track metrics to assess the effectiveness of our communications programs. Requirements: • Bachelor's Degree • Minimum of 8-10 years of relevant experience developing and managing compelling, engaging employee communications initiatives. • Proven competency in strategic communications planning. • Relevant knowledge and experience in digital and mobile communications, storytelling and content creation. Experience working with digital media and formats (intranets, video, mobile, etc.) • Ability to navigate ambiguity in a fast-growing company; confidence to share new ideas; strong influencer and relationship builder. • Passion for science; curiosity to learn. • Excellent writer and storyteller; superior written and verbal communication skills; ability to generate creative content with a varied and thoughtful approach for different audiences. • Detail-oriented; strong organizational, prioritization, and project management skills. • Strong collaborator with the ability to seek and value input. High level of professionalism and confidence to work effectively with employees from all levels of the organization, including senior leaders, functional managers, research scientists and the general employee population. • Proven success working in a fast-paced environment requiring daily flexibility and continuous multi-tasking. Ability to operate with a keen sense of urgency and a results-oriented mindset. Preferred experience: • Previous experience working for a company in biopharma or related industry. • Previous PR/communications agency and corporate experience. #LI-PD1