Celgene

Celgene Seattle, WA, USA
Mar 31, 2020
Full time
Req #: Location: Seattle, Washington, United States Job Category: Sales and Marketing Work Location: 1616 Eastlake Ave 98105 Organization: Sales Representative Employee Status: Full-time Job Type: Regular NOTIFICATION OF JOB OPENINGS Eligible For Employee Referral Program POSITION Sales Representative SUPERVISOR District Sales Manager DEPARTMENT Sales & Marketing PREREQUISITES Bachelor's degree; minimum of 2 years' pharmaceutical sales experience preferred. The Sales Rep is responsible for achieving all territory sales goals through the promotion, sale and support of company products or services in his/her geographic territory. Responsibilities will include, but are not limited to, the following: Direct one-to-one communication with physicians and health care professionals in support of approved product indications. Contacting medical professionals and explaining features and benefits of products offered. Planning and organizing speakers programs in territory. Communicating competitive market intelligence to brand teams and management. Timely and accurate completion of all administrative expectations. Responsible for complying with all federal (PDMA/OIG), state regulations and Celgene's Policies relative to prescription drug sampling. Follows all sampling procedures as detailed within Celgene's Sample Compliance Policies and Procedures Manual. Skills/Knowledge Required : Bachelor's degree; minimum of 2 years' pharmaceutical sales experience preferred. Proven track record that demonstrates top sales accomplishments. Ability to develop relationships with physicians, nurses and ancillary staff within academic hospitals, clinics, and private practice facilities. Demonstrated knowledge of healthcare system processes including reimbursement preferred. Possesses a strong work ethic, ability to develop priorities, and manage time appropriately. Works with all members of a team effectively. Ability to travel over a broad geography is required. This position requires the ability to drive within their assigned territory by automobile (and in some territories to travel by airplane). About Us COMMITTED TO IMPROVING THE LIVES OF PATIENTS WORLDWIDE At Celgene, we seek to deliver truly innovative and life-changing drugs for our patients. Our vision as a company is to build a major global biopharmaceutical corporation while focusing on the discovery, the development, and the commercialization of products for the treatment of cancer and other severe, immune, inflammatory conditions. "At Celgene, we seek to deliver truly innovative and life-changing drugs for our patients." There are more than 300 clinical trials at major medical centers using compounds from Celgene. Investigational compounds are being studied for patients with incurable hematological and solid tumor cancers, including multiple myeloma, myelodysplastic syndromes, chronic lymphocytic leukemia (CLL), non-Hodgkin's lymphoma (NHL), triple-negative breast cancer and pancreatic cancer. As committed as we are to clinical accomplishment, we are equally committed to patient support, which is a guiding principle at Celgene. We believe all who can benefit from our discoveries should have the opportunity to do so. Celgene puts patients first with industry-leading programs that provide information, support and access to our innovative therapies.
Celgene Seattle, WA, USA
Mar 14, 2020
Full time
Req #: Location: Seattle, Washington, United States Job Category: Technical Development Work Location: 400 Dexter Ave N. 98109 Organization: Bioengineering Employee Status: Full-time Job Type: Regular The Potency Group is seeking a talented Scientist to lead projects that characterize the biological activity of autologous and allogenic cell therapies which are currently undergoing clinical trials, including CAR T cell products. The Scientist will lead a team of 1-3 individuals who are developing analytical methods that evaluate the biological activity ( e.g. metabolism, proliferation, and effector function) of novel cell therapies. The successful candidate will facilitate the identification of new functional characterization methods to develop and oversee the design, execution, and analyses of experiments that lead to the development of robust analytical methods. These methods will be used to further understanding of cell therapies, support development of the manufacturing processes, and/or QC release of the drug product. The successful candidate will have a strong background in Immunology or related field and will have experience in projects requiring close collaboration with other groups, such as discovery research, product sciences, process development, and QC. The Scientist will be passionate about developing novel medicines, thrive in an intellectually challenging environment, and enjoy collaborating with a team of likeminded Scientists. Qualifications and Education Requirements • PhD with 2-6 years of experience in the field of Immunology, Cancer Biology, or related field, preferably in an industry setting. • Expertise developing analytical methods that functional characterize T cells, such as their metabolism, proliferative capacity, and/or functional activity ( e.g. cytotoxicity, cytokine secretion, etc .) • Experience with cell culture, ELISAs or similar technology platforms ( e.g. MSD, Luminex, AlphaLISA, etc .), and flow cytometry. • Experienced with authoring and revising test methods, protocols, and technical reports. • Demonstrated experience leading teams and managing direct reports. Preferred Qualifications • Experience with fluorescence microscopy, live cell imaging and analysis ( i.e. IncuCyte), and/or image cytometry • Experience with molecular techniques, such as developing qPCR and next generation technologies such as NanoString, single cell RNA sequencing, and cellular indexing of transcriptomes and epitopes by sequencing (CITE-seq). • High dimensional data analysis ( e.g. CytoBank, viSNE, SPADE, CITRUS, etc .). • Experience with Design of Experiment (DoEs) using JMP or equivalent statistical software. • Proficiency with relative potency methods, 4-PL, robustness assessments, establishing system suitability criteria, critical reagent qualification procedures, analyst training, method transfers, and/or method qualification/validation. • Demonstrated experience qualifying, transferring, validating, performance trending, and/or lifecycle management of analytical methods. Specific Duties • Emphasis on hands-on leadership, mentorship of direct reports, and fostering a creative, collaborative, and accountable working environment. • Responsibility for the development of cell-based immunoassays and next-generation functional interrogation techniques. Proficiency with regulatory requirements, understanding of CMC strategy, awareness of industry trends, and advocate for new technologies. About Us COMMITTED TO IMPROVING THE LIVES OF PATIENTS WORLDWIDE At Celgene, we seek to deliver truly innovative and life-changing drugs for our patients. Our vision as a company is to build a major global biopharmaceutical corporation while focusing on the discovery, the development, and the commercialization of products for the treatment of cancer and other severe, immune, inflammatory conditions. "At Celgene, we seek to deliver truly innovative and life-changing drugs for our patients." There are more than 300 clinical trials at major medical centers using compounds from Celgene. Investigational compounds are being studied for patients with incurable hematological and solid tumor cancers, including multiple myeloma, myelodysplastic syndromes, chronic lymphocytic leukemia (CLL), non-Hodgkin's lymphoma (NHL), triple-negative breast cancer and pancreatic cancer. As committed as we are to clinical accomplishment, we are equally committed to patient support, which is a guiding principle at Celgene. We believe all who can benefit from our discoveries should have the opportunity to do so. Celgene puts patients first with industry-leading programs that provide information, support and access to our innovative therapies.
Celgene Seattle, WA, USA
Mar 11, 2020
Full time
Req #: Location: Seattle, Washington, United States Job Category: Technical Development Work Location: 400 Dexter Ave N. 98109 Organization: Bioengineering Employee Status: Full-time Job Type: Regular Juno Therapeutics, a Celgene Company, is a clinical-stage company developing novel cellular immunotherapies based on two distinct and complementary platforms - Chimeric Antigen Receptors (CARs) and T Cell Receptors (TCRs) technologies. Our goal is to revolutionize medicine by re-engaging the body's immune system to treat cancer. We are looking for a Senior Scientist to lead the development of analytical methods of AAV vector in support of allogeneic CART programs. The ideal candidate has a proven track record of innovation, demonstrated skill set and knowledge in analytical development, and is excited to take on new challenges in a fast-paced and dynamic environment. This incumbent is responsible for overseeing development of AAV characterization and release assays at contract manufacturing organizations (CMOs) and contract test laboratories (CTLs) and coordinating the qualification and validation thereof. These analytical methods will be used to support QC release and in-process testing of AAV vector used for CART /TCR gene delivery. The incumbent will plan and coordinate execution of laboratory studies, analyze experimental data, document results, and present findings to CMC and Core teams. This position requires project leadership and management skills and attention to scientific detail. If you are dedicated to excellence and want to make a difference, we're excited to hear from you! Job Description: Coordinate development and qualification analytical methods to enable AAV process development, release and stability testing at CMOs/CTLs Lead the development of AAV control strategy; work with a cross-functional team to design and execute CMC development plan in support of allogeneic CART programs. Oversee the successful design, execution, interpretation, and documentation of experiments. Support AAV process development effort Contribute to development of novel technologies for gene and cell therapy. Author, review, and approve technical documents, including standard operating procedures, QC test methods, and analytical sampling plans. Contribution to regulatory submissions Summarize and present data in cross-functional team meetings Basic Qualifications: Ph.D. degree in virology, analytical sciences, or related field with 8+ years of experience in AAV analysis and/or drug development Knowledge and experience with AAV biology Demonstrated knowledge of control strategy and analytical development for CMC programs Demonstrated method development experience in techniques such as viral safety and potency assays, viral titer assays, quantitative PCR (qPCR), ELISA, etc. Demonstrated skillset in experimental design, data analysis, interpretation, and presentation. Proven ability to work in a fast-paced environment, meet deadlines, & prioritize work on multiple projects. Strong attention to detail with the ability to handle multiple responsibilities simultaneously Ability to work independently and as part of a team. Strong interpersonal skills including verbal and written communication are essential in this collaborative work environment. Preferred Qualifications: Experience interfacing with contract manufacturing and research organizations, GMP contract test laboratories Demonstrated experience in cross-functional and functional leadership roles. Experience with gene engineering of T cells using viral modalities. Experience authoring technical and regulatory documents. Track record of successful internal and external scientific collaborations. About Us COMMITTED TO IMPROVING THE LIVES OF PATIENTS WORLDWIDE At Celgene, we seek to deliver truly innovative and life-changing drugs for our patients. Our vision as a company is to build a major global biopharmaceutical corporation while focusing on the discovery, the development, and the commercialization of products for the treatment of cancer and other severe, immune, inflammatory conditions. "At Celgene, we seek to deliver truly innovative and life-changing drugs for our patients." There are more than 300 clinical trials at major medical centers using compounds from Celgene. Investigational compounds are being studied for patients with incurable hematological and solid tumor cancers, including multiple myeloma, myelodysplastic syndromes, chronic lymphocytic leukemia (CLL), non-Hodgkin's lymphoma (NHL), triple-negative breast cancer and pancreatic cancer. As committed as we are to clinical accomplishment, we are equally committed to patient support, which is a guiding principle at Celgene. We believe all who can benefit from our discoveries should have the opportunity to do so. Celgene puts patients first with industry-leading programs that provide information, support and access to our innovative therapies.
Celgene Seattle, WA, USA
Mar 11, 2020
Full time
Req #: Location: Seattle, Washington, United States Job Category: Technical Development Work Location: 400 Dexter Ave N. 98109 Organization: Bioengineering Employee Status: Full-time Job Type: Regular Scientist, Gene Editing Process Development Celgene is a global biopharmaceutical company leading the way in medical innovation to help patients live longer, better lives. Our purpose as a company is to discover and develop therapies that will change the course of human health. We value our passion for patients, quest for innovation, spirit of independence, and love of challenge. With a presence in more than 70 countries, and growing - we look for talented people to grow our business, advance our science and contribute to our unique culture. Celgene is developing clinical-stage, novel cellular immunotherapies based on two distinct and complementary platforms - Chimeric Antigen Receptors (CARs) and T Cell Receptors (TCRs) technologies. Our goal is to revolutionize medicine by re-engaging the body's immune system to treat cancer. Celgene is seeking an enthusiastic, self-driven individual to join the viral vector and gene editing process development team. The viral vector and gene editing team develops the processes and technology underpinning critical raw materials used in the manufacturing of engineered T cells. The primary focus of this Scientist will be to ensure the development of GMP manufacturing for site-directed gene editing components including guide RNAs and enzymes. This position will be responsible for providing technical subject matter expertise with internal and external development and manufacturing collaborators including supporting deviation closure, ensuring the processes meet qTPP and specifications, and contributing to comparability assessments due to any process changes. This Scientist will also contribute to wet lab experimental design and execution for viral vector production process development. Responsibilities: Support technology development and on-going activities with external collaborators and service providers (CMOs, CROs) Work with internal collaborators to determine nucleic acid and enzyme Quality Target Product Profiles Manage projects with contract manufacturers for the production of GMP-grade nucleic acids and enzymes Represent viral vector and gene editing process development at CMC and cross-functional team meetings Contribute to experimental design and execution in the viral vector and gene editing process development lab Author technical reports, patents, peer-reviewed publications, and regulatory documents Basic Qualifications: Ph.D in Bioengineering, Biochemistry, Protein Engineering, or related discipline, or equivalent experience (8 - 10 years with B.S. or M.S.) Documented experience manufacturing gene editing raw materials for clinical and research applications Extensive knowledge and experience with CRISPR-Cas systems Effective communication including presentations to convey scientific concepts to research scientists, management teams, and external academic and industrial organizations Proven ability to work effectively as a member of a multidisciplinary team Strong organization, problem-solving, and project management skills with attention to detail Experience and working knowledge of concepts including but not limited to genetic engineering; nucleic acid and enzyme production, purification, and analytical methods; and gene therapy Preferred Qualifications: Previous work interfacing with contract manufacturing and development organizations Experience developing GMP manufacturing processes for globally-regulated products, such as vaccines, biologics, or cell & gene therapies Experience and working knowledge of viral vectors including AAV or lentiviral vectors About Us COMMITTED TO IMPROVING THE LIVES OF PATIENTS WORLDWIDE At Celgene, we seek to deliver truly innovative and life-changing drugs for our patients. Our vision as a company is to build a major global biopharmaceutical corporation while focusing on the discovery, the development, and the commercialization of products for the treatment of cancer and other severe, immune, inflammatory conditions. "At Celgene, we seek to deliver truly innovative and life-changing drugs for our patients." There are more than 300 clinical trials at major medical centers using compounds from Celgene. Investigational compounds are being studied for patients with incurable hematological and solid tumor cancers, including multiple myeloma, myelodysplastic syndromes, chronic lymphocytic leukemia (CLL), non-Hodgkin's lymphoma (NHL), triple-negative breast cancer and pancreatic cancer. As committed as we are to clinical accomplishment, we are equally committed to patient support, which is a guiding principle at Celgene. We believe all who can benefit from our discoveries should have the opportunity to do so. Celgene puts patients first with industry-leading programs that provide information, support and access to our innovative therapies.
Celgene Seattle, WA, USA
Mar 11, 2020
Full time
Req #: Location: Seattle, Washington, United States Job Category: Technical Development Work Location: 400 Dexter Ave N. 98109 Organization: Bioengineering Employee Status: Full-time Job Type: Regular Scientist, Plasmid Production, Viral Vector and Gene Editing Process Development Celgene is a global biopharmaceutical company leading the way in medical innovation to help patients live longer, better lives. Our purpose as a company is to discover and develop therapies that will change the course of human health. We value our passion for patients, quest for innovation, spirit of independence, and love of challenge. With a presence in more than 70 countries, and growing - we look for talented people to grow our business, advance our science and contribute to our unique culture. Celgene is developing clinical-stage, novel cellular immunotherapies based on two distinct and complementary platforms - Chimeric Antigen Receptors (CARs) and T Cell Receptors (TCRs) technologies. Our goal is to revolutionize medicine by re-engaging the body's immune system to treat cancer. Celgene is seeking an enthusiastic, self-driven individual to join the viral vector and gene editing process development team. The viral vector and gene editing team develops the processes and technology underpinning critical raw materials used in the manufacturing of engineered T cells. The primary focus of this Scientist will be to ensure successful GMP manufacturing of plasmid DNA used in viral vector production. This position will be responsible for providing technical subject matter expertise with internal and external development and manufacturing collaborators including supporting deviation closure, ensuring the processes meet qTPP and specifications, and contributing to comparability assessments due to any process changes. This Scientist will also contribute to wet lab experimental design and execution for viral vector production process development. Responsibilities: Support technology development and on-going activities with external collaborators and service providers (CMOs, CROs) Work with internal collaborators including supply chain, quality, and manufacturing sciences and technology to evaluate manufacturing proposals, technologies, and processes Manage projects with contract manufacturers for the production of GMP-grade plasmid DNA Represent viral vector and gene editing process development at CMC and cross-functional team meetings Contribute to experimental design and execution in the viral vector and gene editing process development lab Author technical reports, patents, peer-reviewed publications, and regulatory documents Basic Qualifications: B.S. with 10+ years, M.S. with 8+ years, or Ph.D. with 0-2 years of experience Documented experience manufacturing pDNA for clinical and research applications Extensive knowledge and experience with plasmid manufacturing systems Effective communication including presentations to convey scientific concepts to research scientists, management teams, and external academic and industrial organizations Proven ability to work effectively as a member of a multidisciplinary team Strong organization, problem-solving, and project management skills with attention to detail Experience and working knowledge of concepts including but not limited to genetic engineering, high-density E. coli fermentation, lysis techniques, chromatography, and plasmid analytical methods Preferred Qualifications: Previous work interfacing with contract manufacturing and development organizations Experience developing GMP manufacturing processes for globally-regulated products Experience and working knowledge of viral vectors including AAV or lentiviral vectors About Us COMMITTED TO IMPROVING THE LIVES OF PATIENTS WORLDWIDE At Celgene, we seek to deliver truly innovative and life-changing drugs for our patients. Our vision as a company is to build a major global biopharmaceutical corporation while focusing on the discovery, the development, and the commercialization of products for the treatment of cancer and other severe, immune, inflammatory conditions. "At Celgene, we seek to deliver truly innovative and life-changing drugs for our patients." There are more than 300 clinical trials at major medical centers using compounds from Celgene. Investigational compounds are being studied for patients with incurable hematological and solid tumor cancers, including multiple myeloma, myelodysplastic syndromes, chronic lymphocytic leukemia (CLL), non-Hodgkin's lymphoma (NHL), triple-negative breast cancer and pancreatic cancer. As committed as we are to clinical accomplishment, we are equally committed to patient support, which is a guiding principle at Celgene. We believe all who can benefit from our discoveries should have the opportunity to do so. Celgene puts patients first with industry-leading programs that provide information, support and access to our innovative therapies.