Global Blood Therapeutics

Global Blood Therapeutics South San Francisco, CA, USA
Oct 21, 2021
Full time
SENIOR TAX MANAGER Position Summary: Global Blood Therapeutics (GBT) is seeking a seasoned Senior Tax Manager, reporting to the Tax Director. This individual will be an integral part of both the tax and finance organizations and assist with various tax functions including global tax provision and compliance, R&D tax credit study, tax controversies, and tax research and planning on domestic, state and international tax matters. Essential Duties and Responsibilities: Manage/review the company's global tax provision and related disclosures, (including compiling information for tax provision, review of quarterly and annual income tax provision workpapers, journal entries, and disclosures, documentation of uncertain tax positions, and analysis of tax accounts to ensure compliance and integrity of account balances/financial reporting). Manage and support the external auditors' review of the income tax provision Review quarterly international tax provision packages,...
Global Blood Therapeutics South San Francisco, CA, USA
Oct 20, 2021
Full time
PRODUCT SAFETY SCIENTIST - (REMOTE POSITION) Position Summary: Global Blood Therapeutics is seeking a leader to carry out safety risk management functions for GBT investigational and marketed products. The Product Safety Scientist will support members of GBT Pharmacovigilance Product Safety Teams, including the Product Safety Officer and Product Medical Safety Scientist in carrying out critical pharmacovigilance activities such as signal detection/management, risk management activities, and overall benefit-risk management of assigned products. The Product Safety Scientist will report to the Senior Director of Pharmacovigilance & Risk Management Business, Strategy and Compliance. Essential Duties and Responsibilities: Work with the Product Safety Officer or Product Safety Medical Scientist in carrying out key signal detection activities including completing the signal detection strategy form, review of routine signal detection outputs such as clinical trial (SAES)...
Global Blood Therapeutics South San Francisco, CA, USA
Oct 20, 2021
Full time
ASSOCIATE DIRECTOR, CLINICAL PHARMACOLOGY (Remote Position) Position Summary: This individual provides clinical pharmacology expertise to development projects. The individual will have proficiency in the use of innovative analytical methods to integrate knowledge of pharmacokinetics (PK), biopharmaceutics, pharmacodynamics, patient characteristics and disease states to optimize doses, dosage regimens and study designs and will work closely with the clinical and project teams to create clinical development plans that include assessments of a drug's efficacy, safety, commercial viability and fulfillment of registration requirements. He/she will be an individual contributor on projects. This job can be based anywhere in the United States. Essential Duties and Responsibilities: Represent Clinical Pharmacology on development project teams, as appropriate Lead the execution of clinical pharmacology studies and exposure-response & population PK/PD...
Global Blood Therapeutics South San Francisco, CA, USA
Oct 20, 2021
Full time
DIRECTOR, CLINICAL PHARMACOLOGY (Remote Position) Position Summary: This individual serves as Clinical Pharmacology representative on development teams and provides clinical pharmacology expertise to development projects. The individual will have proficiency in the use of innovative analytical methods to integrate knowledge of pharmacokinetics (PK), biopharmaceutics, pharmacodynamics, patient characteristics and disease states to optimize doses, dosage regimens and study designs and will work closely with the project team to create clinical development plans that include assessments of a drug's efficacy, safety, commercial viability and fulfillment of registration requirements. He/she will be an individual contributor on projects. This job can be based anywhere in the United States. Essential Duties and Responsibilities: Represent Clinical Pharmacology on development project teams Lead the design of the clinical pharmacology component of drug...
Global Blood Therapeutics South San Francisco, CA, USA
Oct 20, 2021
Full time
SENIOR ADMINISTRATIVE ASSISTANT - HEALTHCARE COMPLIANCE & LEGAL Position Summary: Provide primary administrative support to senior executives in the Healthcare Compliance and Legal teams at Global Blood Therapeutics, Inc. (GBT). This is a full-time position. Essential Duties and Responsibilities: Provide administrative support to the VP & Chief Compliance Officer and the VP, Commercial Product Law & Chief Privacy Officer , and the VP and Chief Information Officer Coordinate as requested with the Executive Assistant supporting the Chief Legal Officer, including by providing backup support to the Executive Assistant (who will serve as backup support for this role) Act as a central contact for these senior executives for designated project communications, correspondence and associated documentation Setting up meetings and conference calls, often involving internal personnel and/or external parties, encompassing the use of audio and web-based meeting...
Global Blood Therapeutics South San Francisco, CA, USA
Oct 20, 2021
Full time
SENIOR MANAGER, CLINICAL QUALITY ASSURANCE (GCP) Position Summary: As a key member of the Clinical Quality Assurance function, this individual will serve as a strategic and tactical quality professional in managing compliance related to GCP, pharmacovigilance and other related activities. The individual will be critical in providing compliance guidance to Global Blood Therapeutics, Inc. (GBT) Clinical Development (Clinical Operations, Data Management, Biometrics, Safety/PV), overseeing the GCP audit programs and developing, maintaining and continuously improving the GCP Quality System. Essential Duties and Responsibilities: Promote a culture of compliance and quality within GBT Plan and coordinate continuous improvement of quality processes and systems that assure compliance of clinical study-related activities conducted by GBT and in collaboration with GBT contract research organizations Provide effective oversight of systems cross-functionally in clinical...
Global Blood Therapeutics South San Francisco, CA, USA
Oct 20, 2021
Full time
MEDICAL SCIENCE LIAISON - NEW YORK CITY & NEW JERSEY Position Summary: Global Blood Therapeutics (GBT) is advancing the care of people with sickle cell disease by developing breakthrough therapies, raising awareness and working to increase access to care. The Medical Science Liaison (MSL) is the field-based medical partner responsible for providing accurate and fair-balanced clinical and scientific information related to SCD and GBT medicines (approved and pipeline) to Key Opinion Leaders (KOLs), Health Care professionals (HCPs), payer and government organizations, and other members of the scientific community in compliance with all relevant company policies. In addition, the MSL is responsible for providing medical support for GBT's clinical research programs, registries and facilitation of investigator sponsored trials. In compliant collaboration with their regional partners, the MSL is accountable for driving the local medical strategy and delivering fair-balanced...
Global Blood Therapeutics South San Francisco, CA, USA
Oct 20, 2021
Full time
MEDICAL DIRECTOR, MEDICAL AFFAIRS Position Summary: The Medical Director, Medical Affairs will be a key member of the Medical Evidence team and will help set strategy for both internal Company programs and external facing interactions. The Medical Director is responsible for the design and execution of Phase 3b/4 studies, Externally Sponsored Research Collaborations, Expanded Access Programs, and Product Registries. The Medical Director will work closely with investigators and KOLs to ensure studies will address the needs of providers and patients. The Medical Director, Medical Evidence will report directly to the ED, Medical Evidence. Essential Duties and Responsibilities: Develop protocols and serve as medical monitor of Medical Affairs sponsored studies Coordinate with Company Outreach and Patient Advocacy Team on interactions with community advocates and patient support groups Design, execution, and interpretation of Phase 3b/4 studies, Expanded...
Global Blood Therapeutics South San Francisco, CA, USA
Oct 20, 2021
Full time
SENIOR MANAGER, DIGITAL MARKETING Position Summary: Global Blood Therapeutics (GBT) is seeking a leader to enhance and optimize the Company's focus on digital strategy and execution. The Senior Manager, Digital Marketing in an individual contributor role and will report to the Director, Omnichannel Digital. The candidate will lead the development and execution of an omnichannel plan for engaging customers as the role of virtual engagements continues to evolve. This role promotes and grows marketing's digital footprint to drive desired behavior change. This position will be based in South San Francisco, CA. Essential Duties and Responsibilities: Lead and execute the media plan for HCP and DTC customers. Identify innovative channels and novel opportunities to help grow the brand that fit the speed, agility, and complexity of omnichannel engagement in the hematology market Draw on your demonstrated expertise across a range of practical digital disciplines such as...
Global Blood Therapeutics South San Francisco, CA, USA
Oct 20, 2021
Full time
SENIOR MANAGER, DRUG SAFETY AND PHARMACOVIGILANCE - (Remote Position) Job Summary: The Senior Manager will be integral in the day-to-day functioning and overall development of the Pharmacovigilance team. The incumbent will contribute to a full range of drug safety and Pharmacovigilance activities including vendor management, operations, and compliance. In addition, he/she will also function in a company matrix environment with several key groups including Biometrics, Clinical Operations, Clinical Science, Quality Assurance, and Regulatory Affairs. Essential Duties and Responsibilities: Ensure all safety reports are triaged, processed, reviewed and submitted accordingly per global regulatory requirements and Global Blood Therapeutics (GBT) standard operating procedures Manage and provide oversight for day-to-day interaction with Pharmacovigilance vendor(s) Track cases to completion and adherence to processing timelines Represent Pharmacovigilance in study...
Global Blood Therapeutics Boston, MA, USA
Oct 20, 2021
Full time
SICKLE CELL THERAPEUTIC SPECIALIST ( NYC Region-territory primarily covers MA and RI) Position Summary: Global Blood Therapeutics is seeking an experienced sales specialist for the continued launch of Oxbryta (Voxelotor). The SCTS responsibilities include developing a comprehensive strategic business plan that includes specific, measurable and action-oriented objectives to ensure they achieve/exceed their sales goals. They must demonstrate the ability to target and strategically manage their territory. The SCTS will manage funds and resources efficiently and ethically to maximize sales to ensure ROI. The Sickle Cell Therapeutic Specialist will report directly to the Regional Business Director. This role provides the opportunity to be part of a first in class sales team with responsibility for launching an exciting product that will positively impact and change the course of Sickle Cell treatment. This is a great opportunity to come in on the ground floor and be...
Global Blood Therapeutics South San Francisco, CA, USA
Oct 12, 2021
Full time
MANAGER, REGULATORY OPERATIONS - Remote Position Position Summary: As a Manager, you will be responsible for processes and/or serve as a primary contact for key external relationships within a department. Provide guidance and/or establish framework and create and execute project plans. This will be an induvial contributor role and report to an Associate Director, Regulatory Affairs. Come join us and be part of an exciting and highly collaborative team in this unique time of growth and opportunities at GBT! Essential Duties and Responsibilities: Plan, prioritize, prepare, and submit documents to the FDA and ex-US health authorities using both paper and electronic publishing tools. This includes formatting of Word documents, converting to PDF and finalizing the document preparation For complex submissions, track and manage workflow timelines internally with colleagues Facilitate the internal review and approval process for regulatory submissions Assist in the...
Global Blood Therapeutics South San Francisco, CA, USA
Oct 12, 2021
Full time
ASSOCIATE DIRECTOR, TOXICOLOGY (OPEN TO REMOTE) Global Blood Therapeutics (GBT) is a biopharmaceutical company determined to discover, develop, and deliver innovative treatments that provide hope to underserved patient communities. The company has one FDA-approved therapy for sickle cell disease and multiple investigational therapies in development for the disease. Position Summary: We are seeking for a toxicologist to interact with research and development teams to design critical pathways for nominating compounds as development candidates, design and conduct safety evaluation of development candidates to support clinical trials and registration, and to prepare nonclinical sections of regulatory submissions. This position is an individual contributor role and reports to the Head of Toxicology. Essential Duties and Responsibilities: Serves as Project Toxicologist on project teams in Research and Development Collaborates with Research to develop critical pathways...
Global Blood Therapeutics South San Francisco, CA, USA
Oct 08, 2021
Full time
VICE PRESIDENT, INTELLECTUAL PROPERTY About Global Blood Therapeutics: Global Blood Therapeutics, Inc. (GBT) is a biopharmaceutical company dedicated to the discovery, development and delivery of life-changing treatments that provide hope to underserved patient communities. Founded in 2011, GBT is delivering on its goal to transform the treatment and care of sickle cell disease (SCD), a lifelong, devastating inherited blood disorder. In the United States, GBT has introduced Oxbryta® (voxelotor) tablets, the first U.S. FDA-approved treatment that directly inhibits sickle hemoglobin polymerization, an underlying cause of SCD. The European Medicines Agency has accepted for review GBT's Marketing Authorization Application seeking marketing authorization of Oxbryta in Europe to treat hemolytic anemia in SCD patients ages 12 years and older. GBT is also seeking regulatory approval to expand the potential use of Oxbryta in the U.S. with children with SCD age 4 to 11 years. GBT...
Global Blood Therapeutics South San Francisco, CA, USA
Oct 08, 2021
Full time
VICE PRESIDENT, CORPORATE DEVELOPMENT Position Summary: Reporting directly to the Chief Business and Strategy Officer, the Vice President, Corporate Development will be responsible for identifying, evaluating, and recommending external programs, assets, and companies for potential partnership and/or acquisition by GBT. This role will work with, and lead teams comprised of multiple functions, including research, development, manufacturing, commercial, legal and finance to assess and conduct due diligence of external opportunities. This role will help shape corporate strategy, have high visibility across the organization, and will have substantial interactions with the GBT senior management team. Essential Duties and Responsibilities: Strategy: Work collaboratively with GBT senior management and leaders in Research, Development, and Commercial to set and update corporate strategy and business development goals to support the Company's strategy. Lead corporate valuation...