Apex Life Sciences

Apex Life Sciences Brisbane, CA, USA
Oct 20, 2019
Essential Functions: Answer all incoming calls and route as appropriate and takes messages. Check company voice mail every morning. Route and respond to messages appropriately and delete messages once routed so that the mail box is never full. Welcome visitors/interviewees and announce their arrival to appropriate person. Maintain security by following procedures; monitoring logbook; issuing visitor badges; providing NDA disclosures and obtain signatures from all visitors. Be back up to distribute office mail when HR Assistant and/or Facilities are not available. Responsible for weekly office supply order. Will coordinate with administrative staff on office supply needs. Review order carefully so as to limit incorrect supplies. Work with /Facilities to inventory Costco supplies and to adjust orders accordingly so that inventory levels are appropriate. Responsible for making sure the Costco order is placed weekly which includes the fruit, milk, cheese and monthly snacks. Put the fruit out in Suite F, provide fruit to HR admin to be distributed in Suite A and to Tech Ops Admin to distribute in West Cutting. Main contact for catering and lunch requests. Prepare refreshments and order food for meetings. Assist HR team in scheduling meetings, travel and interview coordination. Assist G&A management team in preparing expense reports. Upkeep of general conference room scheduling, set up and clean up. Ensure all conference rooms are cleaned after the lunch meetings. Create bulletin board announcements for birthday socials, anniversaries, new hires and job postings by comparing the excel reports and announcements provide by HR. May be asked to assist Human Resources with non-confidential filing as needed. Daily tasks and assistance will be assigned by HR Rep as needed to assist HR events and operations. Maintains safe, clean and professional reception area by complying with procedures, rules and regulations. Other projects may be required and will be assigned on an as needed basis. Education, Experience and Skills Requirements: High School Diploma or equivalent, College graduate a plus. A minimum of one to three years of relevant experience Experience using multi line telephone systems Consistent attendance and punctuality is essential for this position to be successful Fluent in Microsoft Office suite applications, particularly Outlook Calendar. Superior oral and written communication skills, attention to detail, professional and creative approach to problem resolution, strong organizational skills, ability to prioritize projects and ability to take initiative Knowledge of general clerical/office systems and office organization required Ability to work with confidential and sensitive data Professional demeanor and positive attitude about work and providing service
Apex Life Sciences San Carlos, CA, USA
Oct 20, 2019
Position Summary : Supervisor, Incoming Document Control is responsible for the management of the document control process and controlled documents. Assist employees with recommendations regarding the release, structure and change of all controlled documentation. Primary Responsibilities : Manages the Document Control team including setting daily priorities; provides feedback to management on individual performance; ensures Document Control personnel have trained to required procedures Responsible for ensuring proper validation performed for the document management system (new software systems, updates, changes to workflows, etc.) Responsible for the development and maintenance of document templates Responsible for ensuring the document approval matrix is updated as needed Ensures annual reviews of controlled documents are performed as required Ensures maintenance of a computer database of all filed documentation that ensures fast retrieval of documents via company intranet website Ensures that historical files for Design History File (DHF), Device Master Records (DMR), Device History Records (DHR), Design Review, Validations, SOP?s, and other quality system documents are maintained. Manage archival activities for controlled documents and validation files to meet requirements of CLIA/CAP, QSR 820, ISO 13485, and State Standards. Assists with the maintenance of company training records. Performs duties of Document Control Coordinator as needed Other duties as assigned Qualifications : Bachelor?s degree or equivalent 3 plus years? experience with electronic document management systems 2 plus years of supervising teams Experience in a regulated environment (CLIA, FDA, ISO) Knowledge, Skills, and Abilities: Computer skills (MS Word, Excel, PowerPoint, etc.) Good writing and communication skills Independent worker, a self-starter with strong organizational and planning skills Ability to work with others, manage small projects, mentor others Knowledge of CLIA, FDA, and/or ISO 13485 Good Documentation practices
Apex Life Sciences San Francisco, CA, USA
Oct 18, 2019
Full time
Apex systems is seeking a Senior Clinical Operations Manager for a San Francisco site location Essential Duties/Responsibilities: Customer & Personalized Service: Continuously evaluate and identify opportunities to drive process improvements that positively impact the customer's experience Manage the day to day operations of the SF cardiac monitoring centers - including the hiring, training and scheduling of all employees through the onsite management team (24/7 operation) Capable and able to work various shifts as necessary Administration and Management - Knowledge of business and management principles involved in strategic planning, resource allocation, staffing, leadership technique, production methods, and coordination of people and resources • Team development and coaching/mentoring direct and indirect reports Monitor the QA, productivity and attendance of all employees Provide on-going over site of the training programs and QA review of the employees for the SF Monitoring Centers Analyze and focus on quality and efficiency measurements Conduct and/or attend weekly staff meetings with supervisors and managers in SF locations as well as with your direct manager Oversee daily staff huddles Problem solving of practice, physician and patient service issues Perform annual performance reviews of direct staff and assist in annual performance review of technicians Education and Experience Requirements: Education: Bachelor's Degree required, Master's Degree preferred Relevant Work Experience: Previous direct management experience over multiple sites required (3-5 years) Mentoring of direct and indirect reports Experience in managing budgets and providing justification for expenditures Experienced with creating and managing to metrics (dashboard) for KPI's Previous experience with HR policies and procedures - such as, hiring, counseling and termination Previous ECG analysis experience preferred, but not required EEO Employer Apex Systems is an equal opportunity employer. We do not discriminate or allow discrimination on the basis of race, color, religion, creed, sex (including pregnancy, childbirth, breastfeeding, or related medical conditions), age, sexual orientation, gender identity, national origin, ancestry, citizenship, genetic information, registered domestic partner status, marital status, disability, status as a crime victim, protected veteran status, political affiliation, union membership, or any other characteristic protected by law. Apex will consider qualified applicants with criminal histories in a manner consistent with the requirements of applicable law. If you have visited our website in search of information on employment opportunities or to apply for a position, and you require an accommodation in using our website for a search or application, please contact our Employee Services Department at or .
Apex Life Sciences South San Francisco, CA, USA
Oct 18, 2019
Full time
Description: Designs and/or executes pathology testing strategies and studies. Leads the conduct of pathologic investigations, reviews and interprets data, communicates results to clients and writes final reports. Serves as Project Scientist, Principal Investigator, Contributing Scientist, Project Leader or Study Director, as applicable. Functions as a subject matter expert and interprets and evaluates the work in areas such as clinical pathology, morphology, histology, histopathology, histochemistry, immunohistochemistry, morphometrics or electron microscopy. Ensures compliance with protocols and all applicable SOPs. Troubleshoots and resolves technical issues in the laboratory when scientific expertise is needed. May introduce new technologies or introduce improvements in existing technologies. Provides advisory functions to clients designing a program or experiment, dealing with specific dataset interpretation, or when appropriate answering questions from regulatory authorities. BASIC SUMMARY: Perform basic to intermediate medical technology procedures. Operate and perform maintenance, including extended maintenance, on analyzers. Able to troubleshoot both basic and more complex problems on analyzers. Maintain equipment records including maintenance and quality control. Perform and review ordered parameters and computer input of raw data. Process additional study samples. Assist in the training and mentoring of less experienced staff. ESSENTIAL DUTIES AND RESPONSIBILITIES: Prepare appropriate paperwork and materials prior to clinical pathology blood collection. Maintain proficient knowledge of hematology, clinical chemistry, coagulation, urinalysis and fecal analysis. Prepare blood slide and cytology smears. Inventory and package differential and reticulocyte blood slides and all biological samples for each study for shipment or storage. Notify the recipient of shipment. Maintain inventory of laboratory supplies and order as needed. Accession samples and raw data into the computer system and review data. Operate, maintain, and troubleshoot of clinical pathology analyzers. Identify and correct problems that may adversely affect test results Perform daily maintenance and quality control of all instruments. Serve as a mentor and/or trainer to less experienced staff. Perform all other related duties as assigned. QUALIFICATIONS: Education: Associated degree (A.A./A.S.) required. Bachelor's degree (B.A./B.S.) or equivalent in medical technology (MT) preferred. Experience: 1 year of experience in a clinical pathology laboratory as a medical technologist. An equivalent combination of education and experience may be accepted as a satisfactory substitute for the specific education and experience listed above. Certification/Licensure: MLT certification (or equivalent) required. MT or MLS certification (ASCP) preferred. Other: Experience with computer software programs is desirable. Effective organizational and leadership skills desired. PHYSICAL DEMANDS: While performing the duties of this job, the employee is regularly required to talk, hear, use hands to handle glassware, tools, or controls; reach with hands and arms; and type at a computer. Occasionally stoops and bends. Frequently lifts and moves up to 10 pounds. Frequently uses a microscope. Stands/walks for up to 90% of the workday (varies). Specific vision abilities required by this job include close vision, color vision, depth perception, and the ability to adjust focus. WORK ENVIRONMENT: While performing the duties of this job, the employee regularly wears protective clothing (scrubs, lab coats, safety glasses, and gloves). Regularly works with biohazards. Occasionally works with sharp objects (e.g., needles). Occasionally works with known and unknown toxins and chemicals The noise level in the work environment is moderate.
Apex Life Sciences Irvine, CA, USA
Oct 15, 2019
Full time
Under the direction of management, the Clinical Reporting Lead will lead the design, development, validation, rollout of reports/dashboards using business intelligence tools (e.g., Spotfire, J-Review) and programs (e.g., SQL, PL-SQL, SAS) used in Clinical Research and Development studies. Responsibilities Include: Analyze Clinical Study design requirements against third party system specifications to support the implementation of electronic systems (e.g., electronic diaries) used in Clinical studies. Assist in the validation of electronic systems and programs as implemented internally or through external vendors according to current regulatory requirements. Act in a project management role managing various study-related projects and initiatives. The Clinical Reporting Lead must be innovative and forward-thinking in support of next generation reporting needs (e.g. advanced and predictive data review). The Clinical Reporting Lead must conduct activities in compliance with all relevant regulations, ICH, PhRMA, and CFR guidelines as well as all Allergan policies, and procedures. Allergan policies include compliance with ethics, environmental health and safety, financial, human resources, and general business policies, requirements and objectives. Education and Experience: BS/BA degree with 6 min. years experience, or MS degree with min. 4 years of experience in Computer Science, Life Science or elated field required Strong knowledge of databases, such as Oracle Knowledge of visualization tools, such as TIBCO Spotfire Knowledge of clinical reporting tools (e.g. Cognos, J-Review, SAS, SQL, etc.) Strong Project Management and Communication skills Ability to work with diverse user groups, lead discussions on and creation of User Requirements and Design documentation Support creation and maintenance of standard report libraries Liaise with other technical personnel in related functions, as needed Strong knowledge of industry specific data standards e.g., CDASH, CDISC ODM/SDTM Strong knowledge of relational databases (e.g., Oracle) Knowledge: * Intermediate knowledge and understanding of Regulatory Guidelines for the use of computer systems in clinical studies Intermediate knowledge of Clinical Data Management and Clinical Programming methodologies as well as current and emerging global industry standards Working knowledge of global standards related to clinical study data management activities (CRF design, data standards, database design, coding and coding dictionaries, etc.) Intermediate knowledge of Research & Development (R&D) and an understanding of regulatory guidelines/requirements related to R&D (e.g., ICH, GCP, safety reporting
Apex Life Sciences San Francisco, CA, USA
Oct 15, 2019
Full time
Summary: The Quality Control Scientist will provide oversight of contract analytical labs and manufacturers. This includes, review of analytical data from release and stability studies and review of method validation protocols and reports. The candidate should have a strong understanding of cGMPs and relevant ICH and FDA regulatory guidelines. Prior hand-on experience working in a QC lab and with root cause analysis for investigations is required. This position will interact and work closely with cross-functional teams, including, manufacturing, quality assurance and regulatory. Responsibilities: Review analytical data packages generated during GMP release/stability testing of drug substance and drug product at the contract manufacturing sites. Assist in investigations and formulate a plan to identify/confirm root cause for anomalous results. Write and/or review method validation and transfer protocols and reports. Write and/or review protocols and reports related to stability studies as well as prepare tables summarizing results from stability studies. Establish a system for tracking and trending release and stability data for batch analysis and shelf life establishment. Initiate change control for internal specifications and regulatory documents. Evaluate and perform risk assessment for change control documents provided by the contract manufacturing sites Establish a reference standard program for drug substance, impurities and degradants. Experience and Skills: B.S. or M.S in Analytical Chemistry or related scientific disciplines with 5+ years of experience in analytical development with minimum of 3+ years of experience in quality control. Prior experience in interacting with contract labs and manufacturing sites is a plus. Hands-on experience with validation and transfer in support of pharmaceutical manufacturing. Proficiency in performing root cause analysis for investigation. Experience with iStability software is a plus Detail oriented with exceptional organizational skills. Excellent written and verbal communication skills.
Apex Life Sciences San Carlos, CA, USA
Oct 14, 2019
Full time
Quality Engineer Opportunity. Position Summary Quality Engineer III supports the quality system processes of the CLIA laboratories and activities associated with CE-IVD kits and software. The QE III works with QE Manager/QA Director to address supplier issues, nonconformances and corrective actions that impact the CLIA laboratory operations. This position will also represent QA on product development projects. Primary Responsibilities Support internal and external audits (CLIA/CAP, ISO 13485, customer) Responsible for CAPA, Deviation, Change Requests and Nonconformance investigation and reporting Write/revise procedures and forms; submit to Document Control and assist with training as needed Perform statistical analysis/hypotheses testing (AQL's etc.) as required Support Quality systems compliance to CLIA, FDA QSR, ISO 13485, and HIPAA Participate in the management of Approved Suppliers Follow established company standard operating procedures and good documentation practices Review manufacturing/QC batch records Other duties as assigned Qualifications Position requirements are a B.S. or equivalent in science, engineering or related field At least 6 years of experience in medical diagnostic, CLIA laboratory, or Life Sciences industry; 3 years' experience in a quality role Audit experience - internal audits, third party audits and/or regulatory audits American Society of Quality certifications (CQE) preferred FICATIONS Knowledge, Skills, and Abilities Knowledge of CLIA/CAP regulations, ISO 13485 standard and/or FDA QSRs (21 CFR 820) Computer skills (MS Word, Excel, PowerPoint, etc.) Good technical writing and communication skills Independent worker, a self-starter with strong organizational and planning skills Has an ability to be productive and successful in an intense work environment Preferred skills: Hands on experience with DNA Isolation and Purification, PCR, Cell Culture, Sequencing, Bioinformatics etc. Demonstrated good judgment, excellent attention to detail, excellent written, verbal communication and interpersonal skills are desired with the ability to be flexible and collaborate on multiple projects Physical Demands and Work Environment Duties typically performed in an office setting Must be able to sit or stand for long periods of time
Apex Life Sciences Chatsworth, Los Angeles, CA, USA
Oct 14, 2019
Full time
General Description: Identify, develop and maintain quality systems to ensure continuous improvement throughout the company in the management of audits to meet customer, regulatory and cGMP requirements. Work with cross-functional teams to facilitate and lead quality improvement activities. Specific Duties and Responsibilities: Ensure adherence to Quality System, and update SOP and Departmental Procedures as necessary. Support internal and external audit programs. Assist in development of checklists and participate in facility walk-throughs. Document and incorporate observations into tracking logs for communication to relevant functions. Develop and maintain general audit documentation, and ensure appropriate employee training conducted and completed as required. Provide timely corrective action to audit findings and coordinate meetings to follow up with responsible parties for completion of actions are within established timelines. Develop and monitor effectiveness checks upon completion of audit related Corrective and Preventive Action (CAPA). Work with cross-functional teams to establish and maintain monthly metrics and KPIs for Quality; use data to drive improvements. Ensure timely completion of reports including Non-Conformance Reports (NCR), Quality Alerts (QAR), and Quality deviations. Help relevant teams develop appropriate short and long term actions to address quality outages. Create & maintain cohesive company information management pertaining to Quality (employee training documentation, equipment calibration master list, etc.). Support the Executive Director of Quality & Regulatory on other special projects. Educational Requirements: Bachelor of Science in chemistry/related field, or combination of education and experience in cosmetics or related (FDA regulated) industry are required. Qualifications: Minimum 3-5 years of experience in Quality in an FDA regulated environment preferred. Experience with OTC or pharmaceutical products preferred. Must be extremely detail oriented. Must be able to work on numerous simultaneous projects to meet established timelines. Excellent verbal and written communication skills required.
Apex Life Sciences Menlo Park, CA, USA
Oct 11, 2019
Full time
Our client, an established Immuno-oncology company in the South Bay is looking to add qualified CLS's to their growing team. Summary The Experienced Clinical Laboratory Scientist is responsible for testing and reporting clinical laboratory results. Responsibilities Performs and reports laboratory testing on clinical laboratory samples used to aide physicians in the diagnosis and treatment of patients Selects, implements, and evaluates results for Quality Control materials used in statistical process control of laboratory assays Troubleshoots assays and equipment for which QC materials fail to perform adequately Participates in activities required to support all necessary licensure for the clinical laboratory, including quality management functions and on-site inspections of the laboratory Responsible for maintaining updated understanding and knowledge of the methods employed in the laboratory and the use of the resulting information by physicians through continuing education activities Trains other CLS personnel and other staff in laboratory methods. May be required to monitor the activities of non-licensed personnel May be required to supervise the activities of the laboratory in the absence of an on site manager May be required to assist in assay development activities. The testing personnel are responsible for specimen processing, test performance and for reporting test results Each individual performs only those high complexity tests that are authorized by the laboratory director and require a degree of skill commensurate with the individual's education, training or experience, and technical abilities Each individual performing high complexity testing must - Follow the laboratory's procedures for specimen handling and processing, test analyses, reporting and maintaining records of patient test results Maintain records that demonstrate that proficiency testing samples are tested in the same manner as patient specimens Adhere to the laboratory's quality control policies, document all quality control activities, instrument and procedural calibrations and maintenance performed Follow the laboratory's established policies and procedures whenever test systems are not within the laboratory's established acceptable levels of performance Be capable of identifying problems that may adversely affect test performance or reporting of test results and either must correct the problems or immediately notify the general supervisor, technical supervisor, clinical consultant, or director Document all corrective actions taken when test systems deviate from the laboratory's established performance specifications Education / Experience California Clinical Laboratory Scientist license in categories appropriate for the area of testing performed Minimum of 1 year of experience in a clinical laboratory setting; preferably with experience in a high complexity molecular testing environment Whether you are seeking a career change or simply interested in becoming part of our network, you will appreciate the ethics guiding each Stratacuity team member. We build lasting relationships with exceptional biopharmaceutical talent and take great care to protect your personal information. Upon receiving your inquiry, you may be directly contacted by a Stratacuity team member to discuss your career goals. We will not share your information with anyone without your direct prior consent.
Apex Life Sciences San Diego, CA, USA
Oct 09, 2019
Full time
Our client is currently focused on utilizing its proprietary E-CEL technology as a direct therapeutic product for improving Hematopoietic Stem Cell Transplants (HSCTs), as well as offering a novel therapy for the regeneration of damaged tissues resulting from both acute and chronic disease. Research Scientist, In Vivo Research & Engineered Cell Biology Position Role & Responsibilities: Conduct pre-clinical in vivo studies, some requiring microsurgery, which test our pre-clinical engineered cell product candidates Analyze data collected from in vivo studies performed Participate or lead in design of in vivo studies Conduct and analyze 2-D and 3-D engineered cell culture and assay experiments relevant to engineered cell product candidates Works collaboratively with fellow AB team members, especially with the AB Research Team and the AB Project Management Team Education/Requirements: Master's degree or PhD in cell biology, molecular biology, biochemistry, immunology or related field and 5 or more years post-graduate hands-on laboratory experience (post-doc or industry experience) covering both in vitro and in vivo work. Enjoys a fast-paced environment where data-based changes are a constant and where proactive 'can do' attitude, sense of urgency and friendly personalities are prized. A track record of the ability to learn new in vivo surgical and modelling techniques is essential Possesses skills related to wet-lab cell-therapy translational research Various cell culture techniques, cell sorting, flow cytometry, qPCR, fluorescent microscopy, antibody assays, intra-cellular signaling detection). A successful candidate must have extensive hands-on experience in performing in-vivo animal modelling work for various potential indications. Previous experience with the following in vivo procedures: Tissue extraction and dissection, IV injection (tailvein, jugular, retro-orbital) and surgical proficiency in murine models (not limited to a specific area: e.g. intratracheal administration, partial hepatectomy, partial pneumonectomy, vascular ligation and/or thrombosis, gastrointestinal and/or vascular anastamoses, etc) Additional Desired Skills and Knowledge. Applicants with experience in various micro-surgical procedures in murine models. The applicant's ability to not only perform such surgical procedures, but also demonstrate knowledge and experience in designing such in vivo experiments would be highly regarded. Applicants with expertise in organ regeneration modelling related to inflammatory and autoimmune disease and injuries would also be preferred. Preference for candidates with experience in the fields of tissue regeneration and/or microvascular biology and vascular niches. Demonstrated expertise in translational in vivo cellular biology involving research and/or product development of cell therapy product is highly desired.
Apex Life Sciences South San Francisco, CA, USA
Oct 08, 2019
Full time
Senior Research Associate, Cell Culture Research Location: South San Francisco, CA Job Description . We are looking for a highly motivated individual to contribute towards the development of therapeutics for treating degenerative diseases. The candidate must have extensive experience in mammalian cell culture including specific experience with stem cell culture and differentiation protocols. The position requires excellent written and verbal skills. Candidate must be highly organized, detail oriented with excellent data collection and data management skills. As a tissue culture research associate at Stratacuity, you'll work under the supervision of our Senior scientist to support and expand Stratacuity cell engineering program. Essential Job Functions and Job Requirements: Small and large-scale culture of mammalian and stem cell lines Generation and differentiation of iPS-cell derived cell lines Participate in the design and optimization of co-culture models Perform cell-based assays such as migration, proliferation, apoptosis and endocytosis Manage material inventory for all cell culture activities Manage more than one type of cell culture at a given time Troubleshoot complex problems in creative and effective ways; actively participate with innovation and/or optimization of established processes to ensure project timelines are met. Compile, process and analyze data; record research procedures and results; file and maintains records. Qualifications BS/MS in Biology, Neuroscience, or related field. 2-5 years with BS or 0-2 years with MS of biotechnology industry experience required. Experience in cell processing and harvest Demonstrated ability to perform technical manipulations using aseptic technique Prior work with mammalian tissue culture practices including iPS -derived cultures is required Proficiency in developing and running-in vitro cell-based functional assays 3D culture and organoid culture experience is preferred Experience in immunology, immunostaining is desirable A strong interest in developing treatments for neurodegenerative diseases Well organized, detail-oriented data collection and data management Excellent written and verbal communication skills Ability to do scientific work independently as well as part of a team, to multitask and demonstrate flexibility, and to meet deadlines in a fast-paced and energetic start-up environment Stratacuity is an equal opportunity employer, and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, protected veteran status, or disability status, or any other characteristic protected by law.
Apex Life Sciences South San Francisco, CA, USA
Oct 07, 2019
Full time
Our client is a late-stage biopharmaceutical company focused on discovering, developing, and commercializing first-in-class muscle activators as potential treatments for people with debilitating diseases in which muscle performance is compromised and/or declining. As a leader in muscle biology research, they are developing small molecule drug candidates specifically engineered to increase muscle function and contractility. Responsibilities: This individual will support skeletal and cardiac muscle programs by running high-throughput biochemical and/or cellular assays for hit identification and lead optimization. Execute electrophysiology experiments for assessment of lead molecules in adult rodent primary cardiomyocytes and run specialized muscle assays, crunch data and generate reports The candidate will use data analysis software to analyze large datasets, generate integrated data analysis reports, and provide results to stakeholders in a timely manner. This individual will work closely with our engineering team to optimize and troubleshoot automation workflow processes. Qualifications: The position requires a BS/MS in biochemistry, cell biology or related field with 3-5 years of research experience in a pharmaceutical, or biotechnology setting. Experience in adult rodent cardiomyocyte isolation preferred Prior experience in biochemical and/or cell-based assay development, execution including data analysis and reporting, is required Familiarity with automation systems, liquid handling devices and experience with data analysis and visualization software Spotfire including Excel, GraphPad, Abase is preferred Quick learner, demonstrate initiative and accountability Strong organizational and time management skills, attention to detail and flexibility Ability to work independently and in a team-based, multi-disciplinary environment
Apex Life Sciences South San Francisco, CA, USA
Oct 07, 2019
Full time
Responsibilities Design and perform proof-of-mechanism as well as proof-of-concept gene editing studies. Hands-on execution of in vitro, ex vivo, and in vivo assays to analyze gene editing of development candidates. Perform cell biology, molecular biology, and biochemistry analyses. Analyze, interpret, and present experimental data. Collaborate with colleagues to ensure timeline adherence and project alignment to meet group and company goals. Support external and internal projects via team meetings, presentations, and reports. Attention to detail and ability to operate independently. Excellent communication and record keeping skills. Essential Qualifications A PhD degree, or equivalent, with 3-5 years of post-doctoral training or industrial experience. Strong background in mammalian gene therapy/editing, RNA biology, DNA repair or related fields. Hands-on experience with a broad range of cell and molecular biology techniques. Experienced with mammalian cell culture (primary cells and cell lines), transient transfections, standard molecular cloning techniques, and cell-based assays. Ability to multitask and readily adapt to change. Preferred Qualifications Familiarity with the field of hematopoiesis and hematological diseases. Experience manipulating primary human hematopoietic cells. Experience with gene-editing (CRISPR/Cas9, ZFNs, TALENs) and DNA/RNA/protein delivery. Knowledge in DNA repair mechanisms and pathways. Broad conceptual expertise with genomics technologies and hands-on expertise with assays including microarray analyses, digital PCR and QPCR, and next-gen sequencing. Experience in FACS, Luminex multiplex assays, and IHC/ICC/IF.
Apex Life Sciences Milpitas, CA 95035, USA
Oct 07, 2019
Full time
Our Client, a bay area leader in stem cell research and specialty genome services is looking for a motivated microinjection specialist. This position is responsible for the animal model division, conducting transgenic animal production through microinjection of DNA/RNA/protein into pronuclear stage embryos or making chimeric animals with injection of targeted ESCs into morula/blastocysts. Skills and Experience Bachelor degree in Biological Sciences or Animal Science. Master degree in the related field preferred. Strong understanding of mammalian genetics. Proficient in transgenic production including rodent handling, sampling, microinjection, embryo transfer, IVF, and gamete/embryo cryopreservation. Minimum of one-year of microinjection experience, such as a weekly injection in an institutional transgenic core. Industry experience preferred. Extensive experience with animal survival surgery. Familiar with general lab operations such as pipetting, centrifuge, and biohazardous disposal etc. Strong organizational and documentation skills Effective verbal and written communication skills. Team player. Proficient at MS Office. Duties and Responsibilities Responsible for daily projects running with animal superovulation, embryo harvesting, microinjection, and embryo transfer to pseudo pregnant recipients. Carry out IVF, cryopreservation, and associated procedures for R&D and service projects. Assist with animal colony management including tracking animal pregnancy, wean, and setting up breeding. Organize and maintain laboratory notebooks and records including methods, procedures, protocols, reports, samples log and storage, and data storage. Work according to safety regulations and facility protocols. Support other departments as needed.
Apex Life Sciences Pleasanton, CA, USA
Oct 06, 2019
Full time
The primary role of the QC Analyst is to conduct cGMP analytical testing for raw materials, in process, finished product, stability and other samples to support development and manufacturing operations. This role will work closely with senior analyst(s) and the Development group to implement analytical methods in Quality Control. This includes but is not limited to the following: Transfer and implementation of analytical methods Write and revise procedures Implement new equipment, perform routine maintenance and troubleshoot equipment issues Routine testing which includes HPLC, viral assays, bioassays, qPCR and other analytical methods Data Analysis, data management and documentation utilizing GDP Support QC System development and implementation Minimum Education/Experience Bachelor's degree (or equivalent) in scientific discipline or a health-related field. 0 to 5+ years relevant industry experience cGMP, Bioassay, viral assay and cell based assay experience a plus Experience in basic molecular biology and recombinant DNA technologies ther Qualifications Strong organizational skills and attention to detail Able to work effectively in a fast-paced, small start-up company environment. Self-motivated, self-disciplined and able to function independently as well as part of a team. Strategic agility, strong critical and logical thinking with ability to analyze problems Strong ability to prioritize, multi-task, and work in an evolving environment Excellent presentation and written/verbal communication skills. Excellent computer proficiency (MS Word, Excel, PowerPoint
Apex Life Sciences Richmond, CA, USA
Oct 06, 2019
Full time
Apex Systems seeking a temp Dev Associate to develop analytical methods to support the development of company's genomic therapies, including genome editing, gene regulation, gene therapy and cell therapy. ESSENTIAL FUNCTIONS: Support AAV vector characterization and method development by conducting TCID50 assay, qPCR, ddPCR and other cell-based or biochemical assays Independently conduct and planning laboratory experiments, in-depth data analysis and data interpretation Compiles / analyzes data and performs computations using data analysis software, spreadsheets, graphing, and curve fitting software Other activities as may be assigned EDUCATION, EXPERIENCE AND SKILLS REQUIREMENTS: Bachelor's or Master's degree in Biological Science or equivalent experience. knowledge of tissue culture, virology molecular biology. 3-5 year minimum relevant industry experience. Can independently conduct experiment according to SOP, and GMP compliance. Familia with basic lab requirement and highly organized. Hands on experience in tissue culture, cell-based bioassay, qPCR, ELISA, qPCR, ddPCR, enzyme activity assay, FACS, and fluorescence -based method development Strong ability to analyze complex data in a quantitative and objective manner Judgment and action skills required to solve commonly encountered problems Knowledge of Microsoft Office products
Apex Life Sciences Richmond, CA, USA
Oct 01, 2019
Full time
Administrative Assistant Essential Functions: Answer all incoming calls and route as appropriate and takes messages. Check company voice mail every morning. Route and respond to messages appropriately and delete messages once routed so that the mail box is never full. Welcome visitors/interviewees and announce their arrival to appropriate person. Maintain security by following procedures; monitoring logbook; issuing visitor badges; providing NDA disclosures and obtain signatures from all visitors. Be back up to distribute office mail when HR Assistant and/or Facilities are not available. Responsible for weekly office supply order. Will coordinate with administrative staff on office supply needs. Review order carefully so as to limit incorrect supplies. Work with /Facilities to inventory Costco supplies and to adjust orders accordingly so that inventory levels are appropriate. Responsible for making sure the Costco order is placed weekly which includes the fruit, milk, cheese and monthly snacks. Put the fruit out in Suite F, provide fruit to HR admin to be distributed in Suite A and to Tech Ops Admin to distribute in West Cutting. Main contact for catering and lunch requests. Prepare refreshments and order food for meetings. Assist HR team in scheduling meetings, travel and interview coordination. Assist G&A management team in preparing expense reports. Upkeep of general conference room scheduling, set up and clean up. Ensure all conference rooms are cleaned after the lunch meetings. Create bulletin board announcements for birthday socials, anniversaries, new hires and job postings by comparing the excel reports and announcements provide by HR. May be asked to assist Human Resources with non-confidential filing as needed. Daily tasks and assistance will be assigned by HR Rep as needed to assist HR events and operations. Education, Experience and Skills Requirements: High School Diploma or equivalent, College graduate a plus. A minimum of one to three years of relevant experience Experience using multi line telephone systems Consistent attendance and punctuality is essential for this position to be successful Fluent in Microsoft Office suite applications, particularly Outlook Calendar. Superior oral and written communication skills, attention to detail, professional and creative approach to problem resolution, strong organizational skills, ability to prioritize projects and ability to take initiative Knowledge of general clerical/office systems and office organization required Ability to work with confidential and sensitive data Professional demeanor and positive attitude about work and providing service
Apex Life Sciences San Francisco, CA, USA
Sep 30, 2019
Full time
Job Function Summary : Involves managing or performing the administrative services or managing the full general operations of an academic or non-academic organization(s). Administrative services include activities in finance and human resources and may also include IT, facilities, or student services. General management activities include long and short range strategic planning in determining the mission and directing all activities of multidisciplinary departments through subordinate management staff. Custom Scope The IND Laboratory Coordinator is a newly created position in our department resulting from significant growth in our faculty size and research output. The incumbent will assist, and be supervised by, the current IND Laboratory Manager who manages a large (approx. 26k square foot) biological lab (BSL2 and BSL3) in the Sandler Neurosciences Center building on the Mission Bay campus. The Lab Coordinator responsibilities will be primarily operational in the laboratory and will parallel those of the Lab Manager, with less overall responsibility. Generally, the Lab Coordinator responsibilities will involve sustentation of the lab's facilities, resources, equipment and lab operations, including, but not limited to: renewal and modification of Biological User Authorizations (BUAs) for BSL2 and 3 labs, updating the Biosafety Manual, interacting with EH&S/USDA/CDC, contract reviews, regulatory reviews, facilities-related requests, some lab supplies and equipment ordering, inventory management, lab personnel training follow-up, overall lab maintenance, and general lab safety and compliance. Department Overview Stratacuity is pursuing a cutting-edge blend of basic science and clinical medicine to provide outstanding care to those suffering from neurodegenerative diseases. Founded in 1999, the IND is committed to creating therapeutics that will halt diseases such as Alzheimer's, Parkinson's, Creutzfeldt-Jakob disease and dementia resulting from traumatic brain injuries. The IND is poised to make serious contributions to this struggle at the frontier of neuroscience and medicine. The mission of the Institute for Neurodegenerative Diseases is to discover causes and develop cures for these illnesses with an innovative program of basic research and clinical medicine. The IND is directed by Nobel Laureate Stanley Prusiner, MD.
Apex Life Sciences South San Francisco, CA, USA
Sep 30, 2019
Full time
Senior Chemist Position Summary Stratacuity is a stealth-mode therapeutics development company pioneering a novel synthetic gene editing technology to treat and cure patients with devastating rare diseases. We seek a motivated and collaborative chemist to join our team. Candidates should have a Bachelor's degree in organic chemistry with minimum of 4 years of industry experience (or minimum 2 years of experience in case of master's degree in organic chemistry) in the field of organic or peptide synthesis. The successful candidate will be part of a dynamic and rewarding work environment where the abilities to effectively communicate and function in a team environment will be essential for success. Responsibilities Successfully prepare, purify and characterize peptide nucleic acid oligomers for Stratacuity's research efforts toward therapeutics development for rare diseases using gene editing technology Maintain PNA monomer and oligomer inventory and Preparing PNA aliquots for delivery to different groups for research purpose Labelling of PNA probes via solution and solid phase methodologies Use and maintain the team's peptide synthesizers, HPLCs, Q-TOF and other instruments for synthesis workflow Development, submission, and maintenance QC data on files as well as on internal database Planning, execution, and documentation of work under the guidance of the lead chemist Independent work on projects and presentation in team meetings Essential Qualifications Bachelor's degree with 4 years of industrial experience respectively in the field of organic or peptide synthesis Hands on experience in the HPLC analysis and purification Excellent communication and record keeping skills Ability to multitask, able to work in a team and readily adapts to changing priorities Preferred Qualifications Master's degree in Chemistry with minimum 2 years of industrial experience respectively in the field of organic or peptide synthesis experience using automated peptide synthesis instrumentation Experience with LC-MS, especially LC coupled with Q-TOF Hands on experience on preparative scale purification of peptides or oligos
Apex Life Sciences Brisbane, CA, USA
Sep 29, 2019
Full time
Essential Functions: Answer all incoming calls and route as appropriate and takes messages. Check company voice mail every morning. Route and respond to messages appropriately and delete messages once routed so that the mail box is never full. Welcome visitors/interviewees and announce their arrival to appropriate person. Maintain security by following procedures; monitoring logbook; issuing visitor badges; providing NDA disclosures and obtain signatures from all visitors. Be back up to distribute office mail when HR Assistant and/or Facilities are not available. Responsible for weekly office supply order. Will coordinate with administrative staff on office supply needs. Review order carefully so as to limit incorrect supplies. Work with /Facilities to inventory Costco supplies and to adjust orders accordingly so that inventory levels are appropriate. Responsible for making sure the Costco order is placed weekly which includes the fruit, milk, cheese and monthly snacks. Put the fruit out in Suite F, provide fruit to HR admin to be distributed in Suite A and to Tech Ops Admin to distribute in West Cutting. Main contact for catering and lunch requests. Prepare refreshments and order food for meetings. Assist HR team in scheduling meetings, travel and interview coordination. Assist G&A management team in preparing expense reports. Upkeep of general conference room scheduling, set up and clean up. Ensure all conference rooms are cleaned after the lunch meetings. Create bulletin board announcements for birthday socials, anniversaries, new hires and job postings by comparing the excel reports and announcements provide by HR. May be asked to assist Human Resources with non-confidential filing as needed. Daily tasks and assistance will be assigned by HR Rep as needed to assist HR events and operations. Maintains safe, clean and professional reception area by complying with procedures, rules and regulations. Other projects may be required and will be assigned on an as needed basis. Education, Experience and Skills Requirements: High School Diploma or equivalent, College graduate a plus. A minimum of one to three years of relevant experience Experience using multi line telephone systems Consistent attendance and punctuality is essential for this position to be successful Fluent in Microsoft Office suite applications, particularly Outlook Calendar. Superior oral and written communication skills, attention to detail, professional and creative approach to problem resolution, strong organizational skills, ability to prioritize projects and ability to take initiative Knowledge of general clerical/office systems and office organization required Ability to work with confidential and sensitive data Professional demeanor and positive attitude about work and providing service